Whole Genome Sequencing News and Research

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Cost-Effective Array Sheds Light on Imprinted Gene Regulation

Researchers from North Carolina State University have developed an array that assesses methylation levels of genes located in imprint control regions (ICRs) within the human genome. The array represents a cost-effective, efficient method for exploring potential links between environmental exposures and epigenetic dysregulation during the early developmental origins of diseases and behavioral disorders.

26 Jul 2024

Dairy Cattle Become Hosts for Avian Flu Transmission

A new study reveals evidence that avian influenza has spilled over from birds to dairy cattle across several U.S. states, resulting in mammal-to-mammal transmission between cows and from cows to cats and a raccoon.

25 Jul 2024

New Insights into the Mechanisms of Gene Misbehavior

Researchers have discovered that a startlingly widespread occurrence in the healthy human population is "gene misbehavior," or the state in which genes are active when they should be inactive.

25 Jul 2024

Developing DNA Test to Eliminate Inherited Blindness in English Shepherd Dogs

Researchers at Cambridge have discovered the genetic mutation that causes English Shepherd Dogs to suffer from progressive retinal atrophy, an irreversible form of blindness.

22 Jul 2024

Study Offers Insights Genetic Variants Influencing Pubertal Timing

Genes can indirectly influence the age at which girls have their first period by accelerating weight gain in childhood, a known risk factor for early puberty, a Cambridge-led study has found.

2 Jul 2024

Genetic Analysis Sheds Light on the Role of Ribosomal DNA Copy Number in Inflammation and Disease

Ribosomal DNA (rDNA) is present in hundreds of copies in the genome, but has not previously been part of genetic analyses.

16 May 2024

Researchers Uncover New Genetic Mutation Linked to Rare Form of Congenital Thyroid Abnormality

A team of researchers from the University of Chicago, in collaboration with the Free University of Brussels and the University of Washington, have uncovered a genetic mutation in a non-coding region of DNA that alters the regulation of the thyroid, leading to a rare form of congenital thyroid abnormality.

9 May 2024

SARS-CoV-2 Variants Detected in Flood-Control Channels Near Homeless Encampments

To better understand COVID-19's spread during the pandemic, public health officials expanded wastewater surveillance.

4 Apr 2024

New Cost-Effective RNA Sequencing Method for Legionella Detection

Legionnaires' disease (LD), a rare and severe type of pneumonia, is a respiratory infection caused by species of Legionella bacteria.

22 Mar 2024

Whole Genome Sequencing Reveals Genetic Influences on Alzheimer's Disease Risk

Identifying genetic variants and the role they play in predisposing people to Alzheimer's disease can help researchers better understand how to treat the neurodegenerative condition for which there is currently no cure.

21 Mar 2024

SPT Labtech to Co-Market Streamlined NGS Library Preparation Workflows for Both PCR and PCR-Free Applications with Roche

SPT Labtech, a global leader in the design, development and manufacture of automated instrumentation and consumables for life science applications, announces its co-marketing collaboration with Roche to deliver a streamlined method for Illumina-compatible Next Generation Sequencing (NGS) library preparation.

21 Mar 2024

First Whole Genome Sequencing of Male Breast Cancer Reveals Potential Treatment Targets

Male breast cancer has distinct alterations in the tumor genome that may suggest potential treatment targets, according to a study by Weill Cornell Medicine investigators.

5 Mar 2024

Tandem Repeat Expansions Linked to Cardiomyopathy Risk, Reveals Study

In the first study to use whole genome sequencing to examine tandem repeat expansions in heart conditions, scientists at The Hospital for Sick Children (SickKids) have laid the groundwork for early detection of and future precision therapies for cardiomyopathy.

28 Feb 2024

Promoter Mutations and Their Association with Autism Risk

The RIKEN Center for Brain Science (CBS) employed genome mutation analysis to investigate the genetics of autism spectrum disorder (ASD) in people and their families. They found that the way a certain type of genetic mutation contributes to the illness differs from that of ordinary mutations.

29 Jan 2024

Study Uncovers Ancestry-Specific Genetic Factors in IBD

The advent of whole genome sequencing technology has prompted an explosion in research into how genetics are associated with disease risk.

17 Nov 2023

New Insights Into Tumor-Immune Interactions Could Lead to More Effective Therapies for Multiple Myeloma

A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine shows how interactions between tumor cells and immune components of the microenvironment can impact treatment responses and outcomes in patients newly diagnosed with multiple myeloma who undergo combination treatments that include targeted immunotherapy.

10 Nov 2023

Research Reveals the Genetic Basis for Song Sparrow Adaptation to Local Climate

Whole genome sequencing of North American song sparrows has revealed the genetic underpinnings for a stunning range of body sizes found throughout the bird's westernmost range-;an adaptation that may make the birds more resilient to climate change.

8 Nov 2023

Researchers Unveil Novel Protein Families and Functions in Microbial Communities

Imagine researchers exploring a dark room with a flashlight, only able to clearly identify what falls within that single beam. When it comes to microbial communities, scientists have historically been unable to see beyond the beam -; worse, they didn't even know how big the room is.

12 Oct 2023

Study Links Autism Gene to Broad Spectrum of Molecular and Cellular Defects

Researchers have used CRISPR gene editing, stem cells and human neurons to study the impact of a gene that is commonly mutated in autism.

6 Oct 2023

Gut Microbes Key to Alleviating Canine Inflammatory Bowel Disease

Researchers at Oregon State University – Cascades have led a study that suggests gut microbes discovered in wild wolves could hold the solution to relieving a prevalent gastrointestinal ailment in domestic dogs.

3 Oct 2023