Zidovudine was approved by the FDA on March 19, 1987, with other antiretroviral agents for the treatment of HIV infection in adults and in children 3 months of age or older. This medicine is also approved for use in HIV infected women to prevent the virus from being passed to their babies during pregnancy and delivery. It is then given to these babies for the first 6 weeks of life. Although the FDA does not approve this practice, zidovudine may be used to prevent workers from getting HIV infection after they accidentally come into contact with the virus on the job. This medicine does not cure or prevent HIV infection or AIDS and does not reduce the risk of passing the virus to other people.
A protein known as polymerase is used by SARS-CoV-2—the coronavirus that is responsible for causing the worldwide COVID-19 pandemic—to replicate its genome within the infected human cells.
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