The TP53 is a gene that instructs the cell to produce tumor protein (p53) ; a vital transcription factor and tumor suppressor. P53 is known as the “guardian of the genome” as it helps in regulating the cell cycle and acts as a tumor suppressor.
Cell growth requires new proteins and the same applies to cancer cells. Scientists analyzed the protein eIF4A3 and its role in the growth of cancer cells.
In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options.
Rare inherited mutations in the body's master regulator of the DNA repair system – the TP53 gene – can leave people at a higher risk of developing multiple types of cancer over the course of their lives.
An RNA molecule involved in preventing the formation of tumors can modify its structure and thus regulate the production of proteins in the cell.
A team of scientists has discovered that the WDR74 protein plays a vital role in metastasis progression in lung cancer and melanoma primary tumors.