siRNA News and Research

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Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA molecules, 20-25 nucleotides in length, that play a variety of roles in biology. Most notably, siRNA is involved in the RNA interference (RNAi) pathway, where it interferes with the expression of a specific gene. In addition to their role in the RNAi pathway, siRNAs also act in RNAi-related pathways, e.g., as an antiviral mechanism or in shaping the chromatin structure of a genome; the complexity of these pathways is only now being elucidated.
Lipid nanoparticles successfully stopped the emergence and development of tumors cells, a new study reveals

Lipid nanoparticles successfully stopped the emergence and development of tumors cells, a new study reveals

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

New supramolecular CRISPR–Cas9 carrier supports much effective genome editing

New supramolecular CRISPR–Cas9 carrier supports much effective genome editing

Experimental "gene silencing" therapy reduces a important driver of heart disease risk by up to 98%

Experimental "gene silencing" therapy reduces a important driver of heart disease risk by up to 98%

Researchers use specific enzymes to tear down viral RNA

Researchers use specific enzymes to tear down viral RNA

Nanoparticles mimicking flu viruses to deliver large biological drug molecules

Nanoparticles mimicking flu viruses to deliver large biological drug molecules

Research establishes a new understanding of how DNA methylation begins in plants

Research establishes a new understanding of how DNA methylation begins in plants

Experts use photothermal nanofibers for the safe engineering of therapeutic cells

Experts use photothermal nanofibers for the safe engineering of therapeutic cells

Study unravels factors involved in risiRNA generation

Study unravels factors involved in risiRNA generation

Viruses buried in marsupials' DNA may help protect against future infections

Viruses buried in marsupials' DNA may help protect against future infections

Study could help develop peptide siRNA carrier for human oral cancer

Study could help develop peptide siRNA carrier for human oral cancer

Successful class of therapeutics attack and shut down unique and harmful genes

Successful class of therapeutics attack and shut down unique and harmful genes

Researchers develop a new method for siRNA stabilization

Researchers develop a new method for siRNA stabilization

Movement of small RNAs underlies mobile RNA interference

Movement of small RNAs underlies mobile RNA interference

Researchers Develop 'Piggyback' Method To Improve Drug Delivery

Researchers Develop 'Piggyback' Method To Improve Drug Delivery

Sensitive technique makes it possible to study the delivery of RNA drugs

Sensitive technique makes it possible to study the delivery of RNA drugs