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CRISPR/Cas method could help save rice crops threatened by climate change

A review of gene editing techniques suggests that the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/Cas) method could be a possible 'savior' for rice crops threatened by climate change and high food demand.

3 Mar 2023

Study shows why a specific gene mutation has opposite effects on mice and human cancers

A small but significant metabolic difference between human and mouse lung tumor cells, has been discovered by Weill Cornell Medicine researchers, explaining a discrepancy in previous study results, and pointing toward new strategies for developing cancer treatments.

27 Feb 2023

High diversity in T-cell receptor genes explains diverse response to infections

Researchers from Karolinska Institutet have demonstrated that the genes that encode the T cell receptors change significantly between individuals and communities, which could help explain why people react differently to certain diseases.

17 Feb 2023

Researchers reveal link immune system genetics and a person's ability to resist new COVID-19 variants

An international team including researchers from the HSE University Faculty of Biology and Biotechnology has found a link between certain genetic features of the immune system and one's ability to effectively resist new waves of COVID-19.

17 Feb 2023

Understanding how tiny organisms thrive after wildfires

UC Riverside researchers have identified tiny organisms that not only survive but thrive during the first year after a wildfire. The findings could help bring land back to life after fires that are increasing in both size and severity.

8 Feb 2023

Revealing the propagation of singlet oxygen along double stranded DNA

Nucleic acid-targeting photodynamic therapy (PDT) is an innovative type of targeted therapy that is currently being studied. This treatment is based on photosensitizers, which are drugs that attach to specific regions in a cell’s DNA.

26 Jan 2023

Potential to rectify various disease-causing mutations enhanced by CRISPR-based enzymes

Designing genome editing strategies for each patient’s mutation would be impractical and expensive because many genetic diseases are induced by diverse mutations spread across an entire gene.

18 Jan 2023

Detecting the extent of natural selection over time

Institut Pasteur, Université Paris Cité, the CNRS, and the Collège de France researchers have employed paleogenomics to trace 10,000 years of human immune system evolution. They examined the genomes of over 2,800 individuals who lived in Europe over the past 10 millennia.

From Institut Pasteur 18 Jan 2023

Grasping how a biological pathway causes stem cells to regenerate or die

According to a recent study conducted by Cedars-Sinai and the University of California, San Francisco (UCSF), altering a cellular process can cause stem cells, which are the cells that give rise to all other types of body cells, to either die or regenerate.

18 Jan 2023

Key genes driving cleft lip and palate identified

A research group headed by the University of Iowa recognized three genes that, when deleted, produce cleft lip or palate, a facial abnormality that affects around one in every 1,600 babies in the United States, according to the US Centers for Disease Control and Prevention.

13 Jan 2023

The continued functioning of circadian clock of cells even after starvation

According to a study that was just published in eLife, cells that have a functioning molecular clock are better able to adapt to changes in glucose supply and can recover from long-term starvation more quickly.

11 Jan 2023

Novel blood biomarker predicts a favorable response to CART cell therapy

A MedUni Vienna research group identified a particularly potent biomarker for clinical response to CAR-T cell therapy, establishing the conditions for the most effective use of this innovative therapy for lymphoma treatment.

11 Jan 2023

Pill-shaped ingestible biosensing system enables continuous monitoring in the intestinal environment

Engineering researchers have developed a battery-free, pill-shaped ingestible biosensing system designed to provide continuous monitoring in the intestinal environment.

6 Dec 2022

Three-year interval appropriate between screening for colorectal cancer

Three years after the first negative multi-target stool DNA test, according to a scientific investigation into the best time to screen for colorectal cancer using non-invasive methods for detecting the disease’s targets in the stool, there were no colorectal malignancies discovered.

1 Dec 2022

Bats use distinct laryngeal structures to generate echolocation and social calls

Bats use distinct structures in the larynx to produce high-frequency echolocation calls and lower-frequency social calls, according to a study by Coen Elemans at the University of Southern Denmark and colleagues, publishing November 29th in the open access journal PLOS Biology.

30 Nov 2022

Revealing the mechanism that ensures genome stability in normal cells

To create new cells, the old cells must divide. This is a constant, frequent, and pervasive process that begins with conception and culminates with death.

30 Nov 2022

Treatment using CRISPR alleviates swelling attacks in hereditary angioedema patients

Hereditary angioedema (HAE) is a rare, genetic disorder characterized by severe, recurring, and unpredictable swelling attacks in various organs and tissues of the body, which can be painful, debilitating, and life-threatening.

11 Nov 2022

RNA-edited regions in brain shed light on neurodevelopment and disease

Numerous sites in the brain where RNA is altered over the course of a person’s lifespan through a process known as adenosine-to-inosine (A-to-I) editing have been identified by Mount Sinai researchers.

3 Nov 2022

Novel technology accurately analyzes cell properties

The potential to examine the features of individual cells is critical in a diverse spectrum of life science applications, from disease diagnosis and therapeutics to identifying pathogenic bacteria and generating cells for bioproduction.

28 Oct 2022

A new outlook on sow breeding using dietary nucleotides

The primary fetal organ systems’ growth and development are strongly influenced by the nutrition status of the mother. Late gestation is when fetal growth is rapidly accelerated, and the nutritional needs of sows rise dramatically as a result of the fetus’ rapid growth and the placenta’s quick expansion.

26 Oct 2022