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Age-Related Hearing Loss Associated With Decrease of Cholesterol in the Inner Ear

Researchers led by María Eugenia Gomez-Casati, the Institute of Pharmacology, School of Medicine, University of Buenos Aires-CONICET; Mauricio Martin, the Institute of Medical Research Mercedes; and Martín Ferreyra, (INIMEC-CONICET-UNC), National University of Córdoba in Argentina report that age-related hearing loss is associated with a decrease of cholesterol in the inner ear.

25 Aug 2023

Microglial Cells Serve as a Stable Viral Reservoir for Latent HIV

Human immunodeficiency virus-1 (HIV) introduces a copy of its DNA into human immune cells as part of its life cycle. Some of these newly infected immune cells can subsequently enter an inactive, latent state for an extended length of time, which is known as HIV latency.

19 Jun 2023

Identifying Drugs to Put the Brakes On Accelerated Aging From HIV Infection, Treatment

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

The Pivotal Role of Combinatorial CRISPR Gene Editing in the Elimination of HIV-1 Infection

Recent research from Temple University’s Lewis Katz School of Medicine and the University of Nebraska Medical Center demonstrates that gene-editing therapy aimed at two targets - HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that aids the virus getting into cells—can effectively eliminate HIV infection.

2 May 2023

Novel inhibitor, hopeaphenol, blocks HIV expression

In the United States, around 1.2 million people are living with HIV as of 2022. Many of these people can now live productive, symptom-free lives thanks to antiretroviral therapies, but a solution that permanently removes HIV from an infected person’s body is still a long way off.

30 Mar 2023

Myeloid cells contribute to a long-lived HIV reservoir, study shows

A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.

28 Mar 2023

Monocytes harbor stable HIV DNA capable of infecting neighboring cells

To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code.

28 Mar 2023

Psychological trauma related to HIV could make it difficult to end the AIDS epidemic

Failing to address the psychological trauma experienced by many older people living with HIV/AIDS will make it difficult, if not impossible, to end the epidemic, according to a Rutgers study.

8 Feb 2023

HIV’s covert methods of evading treatment and immunity

According to Duke Health researchers, the human immunodeficiency virus (HIV) appears to be driven into a latent state, lurking in cells only to erupt once more. This immune response likely evolved to help fight infections.

15 Nov 2022

HIV latent cells produce a possible cure investigation

Researchers from the National Institute of Allergy and Infectious Diseases (NIAID) Vaccine Research Center (VRC) and their collaborators gave a presentation recently at AIDS 2022, the 24th International AIDS Conference in Montreal.

1 Aug 2022

Study finds broadly neutralizing antibodies might help to treat or cure HIV infection

According to research, carefully formulated combinations of broadly neutralizing antibodies might effectively cure HIV while reducing the chance that the virus would evade therapy.

22 Jul 2022

Study reveals why infected individuals cannot get rid of HIV altogether

Thanks to antiretroviral therapy, HIV infection is no longer the life sentence it once was. But despite the effectiveness of drugs to manage and treat the virus, it can never be fully eliminated from the human body, lingering in some cells deep in different human tissues where it goes unnoticed by the immune system.

28 Mar 2022

VOYAGER adjustable tip spacing pipette increases productivity in a real-life situation

INTEGRA Biosciences’ VOYAGER adjustable tip spacing pipettes save time and improve lab productivity, and the company has created a testimonial video showcasing the pipette’s many useful features.

From INTEGRA Biosciences 8 Mar 2022

INTEGRA’s VOYAGER helps HIV researchers get more results in significantly less time

INTEGRA’s VOYAGER adjustable tip spacing pipette is supporting crucial experimental work in longitudinal HIV studies.

From INTEGRA Biosciences 12 Nov 2021

Metabolic restoration could provide natural protection against HIV

The human immunodeficiency virus (HIV-1) particularly attacks CD4 lymphocytes, a type of white blood cell considered to be the conductor of the immune system.

19 Oct 2021

New approach to identify molecular targets for improved prostate cancer therapy

In a new study, researchers have introduced DSER, a technique for identifying molecular targets for enhanced therapy in prostate cancer.

14 Sep 2021

Study may help develop multi-pronged HIV eradication strategies

A team of researchers from the University of California - Davis Health (UC Davis) has made a breakthrough discovery of a unique type of stem cell that reduces the amount of the virus that causes AIDS.

From The University of California, Davis 25 Jun 2021

Novel test detects HIV reservoir in patients more accurately

An innovative test that determines the quality and quantity of inactive HIV viruses in the genes of HIV patients may ultimately give scientists a better idea of effective drugs.

14 Apr 2021

Protein kinases may offer a solution to treat HIV patients with immunodeficiency

A new study indicates that protein kinases, which initiate the process that erodes the body’s immunity, significantly contribute to the immunodeficiency in HIV patients. Drugs that block these protein kinases may offer a solution to treating HIV patients whose immunity is not restored by antiretroviral therapy.

2 Mar 2021

New therapeutic approach to restore the effectiveness of immune cells

Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la recherche scientifique (INRS) has identified a therapeutic approach to restore the effectiveness of immune cells.

10 Feb 2021