Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.
An artery is not like a nose. Or is it? Scientists at La Jolla Institute for Immunology (LJI) have discovered that immune cells in arteries can "sniff" out their surroundings and cause inflammation.
They are at the forefront in the fight against viruses, bacteria, and malignant cells: the T cells of our immune system. But the older we get, the fewer of them our body produces.
The nucleus present inside the cell is surrounded by the nuclear envelope—two layers of phospholipid membrane that obstructs the nucleus from mixing with other parts of the cell—safeguarding the cell’s DNA from outside damage.
Psoriasis is an autoimmune disease that is characterized by patches of red, inflamed skin and painful, scaly rashes.
While dendritic cell immunoreceptor (DCIR) is known to mediate inflammation and bone metabolism, ligands that bind DCIR and the mechanisms underlying DCIR activity remain poorly understood.
When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.
Scientists recently identified the therapeutic benefits to patients receiving mesenchymal stromal cell (MSC) therapy.
New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages.
Using supercomputer-driven dynamic modeling based on experimental data, researchers can now probe the process that turns off one X chromosome in female mammal embryos.
A new study has discovered a two-arm molecule that can effectively deplete cancer-protecting cells within tumors.
Scientists from the Babraham Institute, United Kingdom and VIB-KU Leuven, Belgium, came up with two solutions that can overcome a major clinical limitation of immune cell therapies. The researchers chose mice as their model. The findings were published recently in the journal Science Immunology.
A new study has now identified that it is not possible to generate stable regulatory T cells without Vitamin C or enzymes called TET proteins as much as how one cannot make a banana split without bananas.
Researchers at UC San Francisco are zeroing in on how the immune system may play a role in miscarriage, which affects about a quarter of pregnancies.
Researchers are about to welcome a new one-stop shop for crucial information on how the immune system targets cancers.
When it comes to differentiating between a healthy cell and an infectious cell that has to be killed, the immune system’s killer T cells might make mistakes.
Researchers revealed a predicted causative role for certain cell types in type 1 diabetes by examining its genetic foundations.
Sinai Health researchers have reported that they have uncovered a new mechanism that regulates harmful overreactions in the body’s immune system.
A few patients suffering from melanoma are known to respond quite well to immunotherapy and experience significant and long-lasting tumor regression.
New research has revealed a new role of the steroid receptor coactivator 3, also called SRC-3/NCOA3.
The majority of the molecules in human bodies support the immune system to keep individuals healthy but they do so without reacting excessively, as this may otherwise drive the immune cells to cause problems, like autoimmune disorders.