Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.
Sinai Health researchers have reported that they have uncovered a new mechanism that regulates harmful overreactions in the body’s immune system.
A few patients suffering from melanoma are known to respond quite well to immunotherapy and experience significant and long-lasting tumor regression.
New research has revealed a new role of the steroid receptor coactivator 3, also called SRC-3/NCOA3.
The majority of the molecules in human bodies support the immune system to keep individuals healthy but they do so without reacting excessively, as this may otherwise drive the immune cells to cause problems, like autoimmune disorders.
Effector regulatory T cells, also known as eTreg cells, are a specialized subset of white blood cells that maintain the immune system.
In this interview, Dr. Shalin Naik speaks to AZoLifeSciences about his team's latest research that led to the discovery of a new step in the development of T and B cells that could help us to better understand leukemia.
"Wound healing is one of the most complex biological processes," writes Professor Kazumitsu Sugiura and Dr Kenta Saito from Fujita Health University, Japan, in their article recently published in Nature's Scientific Reports.
Multiple sclerosis (MS) is an autoimmune disorder that develops as immune cells attack the nervous system. T cells are a critical part of our immune system, with a complex array of subtypes - some drive the autoimmune response, while others try to suppress it.
In a new University of California, Irvine-led study, researchers have discovered how regulatory T cells (Treg) are instrumental in limiting the damage caused to the spinal cord in diseases like multiple sclerosis (MS).
An in-depth Garvan study of how the immune system generates effective antibodies provides new insights for vaccine design.
Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors
Climate change and disruption of the ecosystem have the potential to profoundly impact the human body. Xue Ming, professor of neurology at Rutgers New Jersey Medical School, who recently published a paper in the International Journal of Environmental Research and Public Health on the effects of climate change on allergies, autoimmunity and the microbiome -- the beneficial microorganisms that live on and inside the human body -- discusses how the delicate balance of the environment affects conditions such as allergies, autism and immune disorders.
A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and coeliac disease.
High cholesterol kills. In fact, one in four Americans will die from the consequences of atherosclerosis, the buildup of plaques of fat and cholesterol in the arteries. Statins have helped reduce mortality, but millions are still at risk.
University of Alabama at Birmingham researchers have added fresh evidence that early exposure to vaccine-, bacterial- or microbiota-derived antigens has a dramatic effect on the diversity of antibodies an adult mammal will have to fight future infections by pathogens.
Scientists from the Vaccine and Infectious Disease Organization-International Vaccine Centre at the University of Saskatchewan and Temple University have demonstrated that a Salmonella biofilm protein can cause autoimmune responses and arthritis in animals.
The human immune system is expected to guard people against the invasion of external microbes, but at times, it possibly leads to autoimmune disorders.
Scientists from the Diabetes Research Institute at the University of Miami Miller School of Medicine have developed a method allowing for the long-term culture of "pancreatic slices" to study the regeneration of the human pancreas in real time.
Experiments in mice have shown early success in vaccinating them against potentially deadly bacterial infections, such as methicillin-resistant Staphylococcal aureus, or MRSA, the strain resistant to most drug treatments.
AZoLifeSciences speaks to Professor David J. Rawlings from the Seattle children's hospital about recent developments in engineered T cells for type 1 diabetes.