Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.
CRISPR has made headlines in recent years for its potential to help patients with conditions as diverse as blindness and sickle cell disease. However, bacteria were already using CRISPR as an immune system to combat viruses long before humans adopted it to combat genetic disorders.
Therapies based on engineered immune cells have recently emerged as a promising approach in the treatment of cancer.
Researchers at the University of Miami Miller School of Medicine have created RNA molecules that bind to human pancreatic beta cells, which generate insulin and are destroyed in type 1 and type 2 diabetes patients.
Natural killer (NK) cells, which are part of the body’s innate, or first-line, immune response, interact with tumor cells, viral infections, and solid organ transplants, according to a new study.
Scientists have observed for the very first time that insulin-producing cells in the pancreas are attacked by T lymphocytes during the evolution of Type 1 Diabetes.
Researchers at the La Jolla Institute for Immunology have uncovered novel genes associated with the risk of autoimmune disorders in the CD4+ “helper” T cell subset.
An artery is not like a nose. Or is it? Scientists at La Jolla Institute for Immunology (LJI) have discovered that immune cells in arteries can "sniff" out their surroundings and cause inflammation.
They are at the forefront in the fight against viruses, bacteria, and malignant cells: the T cells of our immune system. But the older we get, the fewer of them our body produces.
The nucleus present inside the cell is surrounded by the nuclear envelope—two layers of phospholipid membrane that obstructs the nucleus from mixing with other parts of the cell—safeguarding the cell’s DNA from outside damage.
Psoriasis is an autoimmune disease that is characterized by patches of red, inflamed skin and painful, scaly rashes.
While dendritic cell immunoreceptor (DCIR) is known to mediate inflammation and bone metabolism, ligands that bind DCIR and the mechanisms underlying DCIR activity remain poorly understood.
When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.
Scientists recently identified the therapeutic benefits to patients receiving mesenchymal stromal cell (MSC) therapy.
New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages.
Using supercomputer-driven dynamic modeling based on experimental data, researchers can now probe the process that turns off one X chromosome in female mammal embryos.
A new study has discovered a two-arm molecule that can effectively deplete cancer-protecting cells within tumors.
Scientists from the Babraham Institute, United Kingdom and VIB-KU Leuven, Belgium, came up with two solutions that can overcome a major clinical limitation of immune cell therapies. The researchers chose mice as their model. The findings were published recently in the journal Science Immunology.
A new study has now identified that it is not possible to generate stable regulatory T cells without Vitamin C or enzymes called TET proteins as much as how one cannot make a banana split without bananas.
Researchers at UC San Francisco are zeroing in on how the immune system may play a role in miscarriage, which affects about a quarter of pregnancies.
Researchers are about to welcome a new one-stop shop for crucial information on how the immune system targets cancers.