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A high-throughput drug discovery assay for the endoplasmic reticulum aminopeptidase 1

The January 2023 issue of SLAS Discovery contains a collection of four full-length articles and one technical brief covering cancer research, high-throughput screening (HTS) assay development and other drug discovery exploration.

31 Jan 2023

bit.bio partners with Automata to automate a key aspect of its production of iPSC derived human cells

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From Automata 26 Jan 2023

TTP introduces Cellular Origins, a TTP Company focussed on delivering scalable manufacture of cell and gene therapies

New company created to enable commercial manufacture of new cell and gene therapies.

From TTP plc 17 Jan 2023

New bioprinting platform to replicate tumors in 3D spheroids

Bowel cancer patients could in future benefit from a new 3D bioprinting technology which would use their own cells to replicate the complex cellular environment of solid tumors in 3D models.

3 Nov 2022

New imaging technologies to evade immune responses of Candida albicans

Researchers from the Monash Biomedicine Discovery Institute have demonstrated how the common fungus Candida albicans evades immune responses using newly discovered imaging technologies. The researchers claim that this involves a fungus that can shape-shift in an “alien-like” manner to escape immune cells.

21 Sep 2022

Re-defining the limits of single batch assay stabilisation

In response to increasing demand for stabilised molecular diagnostic assays, we have significantly increased our single batch lyophilised reagent bead manufacturing throughput to 300,000 reactions per freeze drying run and are now progressing towards a capacity of 100 million tests per annum.

From Biofortuna Limited 22 Aug 2022

Optimised microplate for cannabis sample processing

Porvair Sciences has developed a 2 ml 96-well microplate whose design is optimised for labs processing cannabis samples for analysis of Tetrahydrocannabinol (THC) and Cannabidiol (CBD).

From Porvair Sciences Limited 29 Jul 2022

Challenges in Drug Discovery; Where are we now, and where are we going?

As part of our SLAS Europe 2022 coverage, we speak to Steve Rees, Vice-President of Discovery Biology at AstraZeneca, about the challenges currently faced by the drug discovery sector.

From Society for Laboratory Automation and Screening (SLAS) 8 Jul 2022

How Important is the European Ecosystem to Life Sciences Research?

As part of our SLAS Europe 2022 coverage, we speak to Jan Lichtenberg, vice president of SLAS, about the role Europe plays within life sciences research.

From Society for Laboratory Automation and Screening (SLAS) 7 Jul 2022

How can High-Content Screening accelerate Drug Discovery?

As part of our SLAS Europe 2022 coverage, we speak to Professor Jeremy Simpson from the University College Dublin about the role high-content screening can play in accelerating drug discovery.

From Society for Laboratory Automation and Screening (SLAS) 6 Jul 2022

Automated barcode applicator for microplates and Petri dishes

Porvair Sciences announce eGecko² – an automated barcode application system that provides the ideal high throughput solution for precisely applying barcode labels onto racks of plates and Petri dishes.

From Porvair Sciences Limited 22 Jun 2022

Robotic finger covered with living skin tissue can heal itself

Researchers from the University of Tokyo pool knowledge of robotics and tissue culturing to create a controllable robotic finger covered with living skin tissue.

20 Jun 2022

INTEGRA solutions helping to support a new generation of RNA sequencing

INTEGRA Biosciences’ electronic handheld pipetting solutions are helping to improve the throughput capacity of bulk RNA barcoding and sequencing (BRB-seq) at Alithea Genomics in Switzerland.

From INTEGRA Biosciences 17 Jun 2022

Researchers develop advanced machine learning to count blood cells

The use of machine learning to do blood cell counts for illness detection rather than costly and often less reliable cell analyzer devices has proven labor-intensive, as the training of the machine learning model requires a tremendous amount of manual annotation activity by humans.

27 May 2022

New open-source tool automates RNA analysis, likely to encourage research and drug development

Scripps Research scientists have introduced a new software tool for examining RNA (ribonucleic acid) molecules, which play a variety of important roles in living things.

10 May 2022

Dotmatics Biology Solution for Antibody Discovery streamlines data collection and workflows to accelerate antibody research and therapies

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From Dotmatics 5 May 2022

IDS Vision Channel: Free web session on "Smart Farming" with guest speakers

Image processing can be used to accelerate, control and optimise processes. When artificial intelligence comes into play, the range of applications becomes even wider.

From IDS Imaging Development Systems GmbH 4 May 2022

New automated system behaves as a promising tool to treat human bloodstream infections

When treating patients with acute infections, healthcare professionals must be able to quickly and properly determine which antibiotics are most effective in combating the disease.

20 Apr 2022

Understanding the role of ORF8 viral gene in COVID-19 infection and outcomes

A research team led by Jae Jung, PhD, Director of Cleveland Clinic's Global Center for Pathogen & Human Health Research, has uncovered the critical role a viral gene, ORF8, plays in infection and disease outcomes of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19.

8 Apr 2022

How Important are Data Clouds to Life Sciences Research?

In this interview, we speak to Mike Tarselli, CSO of TetraScience, about their Tetra data cloud and the role it plays within scientific data analysis.

From TetraScience, Inc. 31 Mar 2022