Biochemistry News and Research

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Probing Plasma Membrane Dynamics with Cryo-Electron Microscopy

Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood.

25 Jul 2024

RNA Technology Enables Precise Control of Gene Networks

Scientists have created a smart RNA that can control networks in response to different signals by converting guide RNAs, which normally direct enzymes. The scholarly community is paying close attention to this ground-breaking study.

23 Jul 2024

Unveiling the Power of mRNA and LNPs in Modern Medicine

Consider a situation in which an expert hacker has to upload vital software to update a central server and stop a potentially fatal virus from causing havoc on a sizable computer network.

10 Jul 2024

Small Molecules Offer Precise Control Over Splicing in Gene Expression

The correct functioning of cells relies heavily on the ability to finely control gene expression, a complex process by which the information contained in DNA is copied into RNA to eventually give rise to all the proteins and most of the regulatory molecules in the cell.

3 Jul 2024

Targeting Pseudomonas aeruginosa Cell Wall Stress for Biofilm Control

Antibiotic resistant bacteria are experts in evolving new strategies to avoid being killed by antibiotics.

2 Jul 2024

New High-Throughput Platform for Rapid Evaluation of Plant-Derived Molecules

Plants are powerhouses of molecular manufacturing. Over the eons, they have evolved to produce a plethora of small molecules -; some are beneficial and valuable to humans, others can be deadly.

28 Jun 2024

New Model Unveils Synaptic Mechanisms in Neurological Diseases

Newly released research from Colorado State University provides basic answers to questions regarding brain cellular connectivity that may be helpful in the development of therapies for neurological conditions like schizophrenia, epilepsy, and autism.

27 Jun 2024

Unveiling a Reversible Pre-Commitment Stage in Cell Division

Researchers at Weill Cornell Medicine have uncovered a surprising new step in cell division.

27 Jun 2024

Bridge RNA: The Revolutionary Tool in Genetic Recombination

In a leap forward for genetic engineering, a team of researchers from the Arc Institute have discovered the bridge recombinase mechanism, a precise and powerful tool to recombine and rearrange DNA in a programmable way.

27 Jun 2024

AI-Driven Design of Soluble Protein Analogs for Drug Discovery and Antibody Development

Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins: when molecules of a drug candidate bind to these proteins, like a key going into a lock, they trigger chemical cascades that alter cellular behavior.

24 Jun 2024

New Cold-Sensing Protein Discovery Could Revolutionize Pain Management

The only available treatments for millions of people with chronic pain worldwide frequently involve the use of opioids, which pose the risk of addiction and overdose.

24 Jun 2024

Breakthrough Imaging Reveals the Dynamics of the Brain's Fast-Acting Kainate Receptor

New groundbreaking images of one of the brain's fastest-acting proteins are providing critical clues that may lead to the development of targeted therapies to treat epilepsy and other brain disorders.

18 Jun 2024

Simplified Proteomics Method Could Open the Door Toward Precision Medicine

Proteins are workhorses that carry out most of the biological functions in our cells.

12 Jun 2024

Multiciliated Cell Differentiation Regulated by an Alternative Cell Cycle

A fertilized egg can develop into a baby through the amazing process of cell division, while a malignant cell can become a malignant tumor. Since there is so much on the line, nature maintains strict control over it through a mechanism known as the cell cycle that scientists once believed they thoroughly understood.

7 Jun 2024

Novel Lipopeptide from Serratia marcescens Shows Promise Against Staphylococcus aureus Infections

A novel antibacterial lipopeptide produced by the bacterium Serratia marcescens has been shown to be highly effective in killing Staphylococcus aureus – one of the most important pathogens occurring in humans.

7 Jun 2024

Study Unveils Key Mechanism of Telomere Maintenance by CST–Polα/Primase

The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, resulting in telomere disorders with serious health consequences.

6 Jun 2024