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Researchers Discover New Role of Mitofusin 2 in Cellular Health

Researchers from Cologne, Bochum, Padova and Angers have discovered a novel connection between mitochondrial function, protein quality control and cellular health, whose failure could be the leading cause in the currently incurable neurological disease Charcot-Marie-Tooth (CMT).

17 Feb 2025

Study Reveals Mechanisms Behind Bacterial Flagellar Motor Movement

When speaking of motors, most people think of those powering vehicles and human machinery. However, biological motors have existed for millions of years in microorganisms.

14 Feb 2025

New Research Sheds Light on How Cells Manage Fat Recycling

Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have made a breakthrough in understanding how our cells manage to stay healthy by recycling important fat molecules.

13 Feb 2025

Understanding the Complex Architecture of the Minor Spliceosome

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome continuously separates the coding and non-coding regions of our genes – and it's doing this even as you read these lines.

13 Feb 2025

Understanding Plant Repair of Light-Damaged Photosystems

More than two billion years ago, cyanobacteria started to produce oxygen in the primarily toxic atmosphere of Earth.

11 Feb 2025

New Study Reveals Energy-Saving Strategies in Neuronal Protein Synthesis

Nerve cells use incredible energy-saving techniques while still carrying out their primary functions.

10 Feb 2025

High-Resolution Images Reveal How Cells Discard Faulty Spliceosomes

A sophisticated molecular machine, the spliceosome, ensures the accurate assembly of genetic information from the genome into mature mRNA after it has been transcribed into mRNA precursors.

10 Feb 2025

New Technique Simplifies Search for Life Beyond Earth

Researchers have long investigated what type of life exists beyond Earth and how we can find it. A new method focuses on looking for one of the most basic signs of living microbes – movement.

8 Feb 2025

Genetic Map of Yerba Mate Offers Insight into Evolution of Caffeine Biosynthesis

Yerba mate, along with tea and coffee, is one of the world's most popular caffeinated beverages. Widely consumed in South America, this remarkable plant is rich in diverse, bioactive compounds that contribute many health benefits.

5 Feb 2025

Danish Protein Analysis to Revolutionize the Biopharma Industry’s Impurity Control

Since 2007, the contract laboratory Alphalyse A/S has developed and refined a new method of impurity analysis in biological pharmaceuticals based on mass spectrometry (MS).

3 Feb 2025

New Numbering System Advances Adhesion GPCR Research

Adhesion GPCRs are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for therapies.

29 Jan 2025

Unique Genetic Signature Predicts Bacteria's Potential to Develop Antibiotic Resistance

Antibiotic resistance is a global public health crisis responsible for more than a million deaths annually.

29 Jan 2025

Microglia Response Varies Between Male and Female Mice

A collision happens. Someone is hurt, a head injury, a concussion. Just as the first responders arrive to help the person, inside the brain, another "crew" of responders is busy clearing debris and repairing injured tissue.

22 Jan 2025

Novel Fluorescent Probes Illuminate Cholesterol Dynamics in Live Cells

The quest to find solutions for Alzheimer's disease and other neurodegenerative disorders continues to be one of the most urgent priorities in brain research. According to Maciej J. Stawikowski, Ph.D., an Assistant Professor of Chemistry and Biochemistry at the Charles E. Schmidt College of Science at Florida Atlantic University, the secret might be in comprehending how lipids like cholesterol flow through cells and impact communication.

20 Jan 2025

Oxygen Sensor Protein Offers Solution for Enhancing Nitrogen Fixation in Plants

A small helper for big tasks: an oxygen sensor protein protects the enzymatic machinery of biological nitrogen fixation from serious damage.

17 Jan 2025

Scientists Uncover Key Plant Metabolite to Block Biofilm Development

If your teeth have ever felt fuzzy after skipping a brushing, you've encountered biofilm-a slimy bacterial layer that clings to surfaces. In medical settings, biofilms make infections harder to treat when they form protective shields for bacteria on devices like catheters and implants.

13 Jan 2025

Illuminating RNA Function with Innovative Bioluminescent Probes

The molecule that reads the genetic data contained in DNA is called RNA. Researchers at the University of California, Irvine have found a method to tag RNA with a glowing bioluminescent molecule, which enables them to track RNA in real time as it travels throughout the body.

10 Jan 2025