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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

New gel electrophoresis method allows rapid diagnosis of biomarkers by mass spectrometry

Polyacrylamide gel electrophoresis is a technique that allows high-resolution isolation of proteins separated from biological specimens.

22 Feb 2021

Electrochemical sensor for rapid detection of multiple sepsis biomarkers in whole blood

Many life-threatening medical conditions, such as sepsis, which is triggered by blood-borne pathogens, cannot be detected accurately and quickly enough to initiate the right course of treatment.

15 Feb 2021

Study finds the brain is changed by caffeine in utero

New research finds caffeine consumed during pregnancy can change important brain pathways that could lead to behavioral problems later in life.

10 Feb 2021

Unique proteomics-based technology can help diagnose breast cancer more accurately

Breast cancer could be identified more precisely than existing methods using blood specimens and exclusive proteomics-based technology.

28 Jan 2021

TBI: Increased levels of immune cells promote inflammation that may worsen brain damage

Immediately after a traumatic brain injury and as long as one year later, there are increased levels of immune cells called ILCs in the brain promoting inflammation, which can worsen brain damage, scientists report.

27 Jan 2021

Continuous in vitro monitoring could lead to faster, more effective treatments for chronic conditions

A world-first discovery by researchers at Monash University and The University of Queensland could lead to faster and more effective treatments for chronic health complications, such as cardiovascular disease and cancer, with 'fluorescent' in vivo biosensors.

27 Jan 2021

Study: Vegan diet has broad effect on children's metabolism

The study concludes that vegan diet has a broad effect on children's metabolism. Serum biomarker levels for vitamins A and D, cholesterol forms and essential amino acids were significantly lower in children on vegan diet compared to age-adjusted omnivores.

22 Jan 2021

Targeting RNA splicing can trigger antiviral immune pathways in triple-negative breast cancers

Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the body's immune response.

15 Jan 2021

Protein phosphatase inhibition could contribute to the treatment of cancer, other diseases

The abundant presence of an enzyme known as low molecular weight protein tyrosine phosphatase (LMWPTP) in tumor cells has long been considered an indicator of cancer aggressiveness and metastatic potential.

13 Jan 2021

Proteogenomic study may lead to more effective treatments for head and neck squamous cell carcinoma

Proteogenomic studies may provide a better understanding of how to match cancer patients with an effective treatment for their specific cancer.

8 Jan 2021

Sugar-binding protein could serve as a useful biomarker for patients at risk of sepsis

According to a research team headed by the University of Connecticut Health, a sugar-binding protein could drive terrible inflammation and worsen sepsis—a disease that kills over 270,000 individuals per year in the United States alone.

5 Jan 2021

Scientists develop a new gene biomarker identification method for toxicity testing

Companies like agrochemicals must check extensively for possible toxicity when they develop new products, before they can obtain regulatory approval.

21 Dec 2020

Researchers discover protein that may trigger lung scarring

Systemic sclerosis is an autoimmune disease associated with inflammation and fibrosis, or scarring, that affects organs including the skin, heart, kidney and lungs.

18 Dec 2020

Researchers develop a diagnostic tool for amyotrophic lateral sclerosis

Infrared analyses of neuronal proteins provide information on molecular changes in patients with ALS. This helps to verify their diagnosis.

10 Dec 2020

Researchers demonstrate strategy to control chemical reactions using antibodies

Antibodies are remarkable biomarkers: they are the cues that provide us with indications about many diseases and how our immune system counter them. Now a group of scientists from the University of Rome, Tor Vergata (Italy) has found a way to repurpose them so that they can trigger a specific chemical reaction.

8 Dec 2020

Disturbances in the gut microbiome may explain major depressive disorder

Researchers have successfully detected three bacteriophages, 50 fecal metabolites, 47 bacterial species that were considerably more or less abundant in patients with major depressive disorder (MDD) when compared to healthy controls. The study involved 311 individuals.

4 Dec 2020

Biomarker News and Research

New gel electrophoresis method allows rapid diagnosis of biomarkers by mass spectrometry

Electrochemical sensor for rapid detection of multiple sepsis biomarkers in whole blood

Study finds the brain is changed by caffeine in utero

Unique proteomics-based technology can help diagnose breast cancer more accurately

TBI: Increased levels of immune cells promote inflammation that may worsen brain damage

Continuous in vitro monitoring could lead to faster, more effective treatments for chronic conditions

Study: Vegan diet has broad effect on children's metabolism

Targeting RNA splicing can trigger antiviral immune pathways in triple-negative breast cancers

Protein phosphatase inhibition could contribute to the treatment of cancer, other diseases

Proteogenomic study may lead to more effective treatments for head and neck squamous cell carcinoma

Sugar-binding protein could serve as a useful biomarker for patients at risk of sepsis

Scientists develop a new gene biomarker identification method for toxicity testing

Researchers discover protein that may trigger lung scarring

Researchers develop a diagnostic tool for amyotrophic lateral sclerosis

Researchers demonstrate strategy to control chemical reactions using antibodies

Disturbances in the gut microbiome may explain major depressive disorder

World’s largest proteomics centre accelerates biomarker discoveries to improve people’s lives

Novel DNA-based nanogel for targeted delivery of chemotherapeutics

New way to predict who will respond to cancer therapies that block Wnt production

Presence of microbes in the lung can modulate lung cancer pathogenesis

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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