A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.
To help with early tumor diagnosis and tumor localization, researchers have devised a technology that concurrently detects many cancer-specific DNA circulating hallmarks.
According to a recent JAMA study by scientists at the University of Pittsburgh and UPMC, a nasal swab to screen for three types of bacteria can reveal whether or not antibiotics are likely to be beneficial in children with suspected sinusitis.
By combining multiple advanced technologies into a single system, EPFL researchers have made a significant step forward in diagnosing neurodegenerative diseases (NDDs) such as Parkinson's disease (PD) and Alzheimer's disease (AD).
Now that the emergency phase of the COVID-19 pandemic has ended, scientists are looking at ways to surveil indoor environments in real time for viruses.
Three previously undiscovered membrane proteins in ovarian cancer have been discovered by a study led by Nagoya University in Japan.
Researchers led by McMaster University professor Gregory Steinberg and postdoctoral research fellow Dongdong Wang have uncovered a key mechanism for promoting weight loss and maintaining the burning of calories during dieting.
Urine is one of the alluring sources for early and sensitive biomarker discovery because it can accumulate and indicate changes in the human body while still being obtained non-invasively.
Infection risk is always there in those with compromised immune systems. Pseudomonas aeruginosa, a typical environmental bacterium, can colonize several body areas, including the lungs.
ALS (amyotrophic lateral sclerosis) is a deadly neurodegenerative disease that attacks nerve cells in the brain and spinal cord, progressively robbing individuals of their capability to speak, move, eat, and breathe.
Conditions like ulcerative colitis and Crohn's disease, which cause inflammation in the body, can be identified or tracked by measuring a protein called calprotectin.
Transformation aimed at revolutionizing next generation scientific breakthroughs that solve the world’s greatest health challenges
When you need a bit of motivation, it often has to come from within. New research suggests cancer-fighting immune cells have found a way to do just that.
Prostate cancer frequently metastasizes to the bone and is incurable. Moffitt Cancer Center researchers are working to identify new treatment options for this subset of patients.
For the first time, a global study group headed by investigators at Virginia Commonwealth University has found markers that might point out early if a person is susceptible to schizophrenia in the early stage itself.
Researchers investigating the growth of a roundworm discovered a tiny RNA molecule that controlled the expression of specific genes in the early 1990s. This resulted in the discovery of microRNAs (miRNAs), which are now known to exist in all forms of life. These molecules, it turns out, play vital functions in a variety of biological processes.
Like the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physicians much about a patient's metastatic prostate cancer.
According to a study conducted by UCLA, patients with advanced melanoma responded differently to PD-1 checkpoint blockade immunotherapy depending on a variety of variables, including whether or not they had previously received CTLA-4 blockade, another type of immunotherapy.
This study is led by Dr.Ningli Wang and Dr.Yuan Xie (Beijing Tongren Hospital, Capital Medical University), they provide evidence that retinal microvasculature is a potential biomarker for cerebral microvasculature changes and acute mountain sickness(AMS) development during risk assessment of individuals at high altitudes.
Prostate cancer tumors harboring BRCA1/2 mutations are exceptionally sensitive to PARP inhibitors, while genomic alterations in other DNA damage response (DDR) genes are less responsive.
Food analysis laboratories can provide an answer to questions like “Was the salmon for dinner really caught wild or did it come from aquaculture? What to make of the alleged ‘biolabel quality’ of the shrimp for the seafood salad? And was the chicken for the Sunday roast really allowed to spend its life in the open air?” to a limited extent.