A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.
Scientists from Buck Institute have identified and are now developing an innovative, non-invasive biomarker test that could help quantify and track the performance of senolytics—a class of drugs that selectively destroy senescent cells.
Fish oil supplements are a billion-dollar industry built on a foundation of purported, but not proven, health benefits. Now, new research from a team led by a University of Georgia scientist indicates that taking fish oil only provides health benefits if you have the right genetic makeup.
Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology.
A new study shows that the advantageous effects of gene therapy can be observed several decades after the body clears the transplanted blood stem cells.
During biomarker testing, certain disease-associated molecules are examined to estimate the progression of a disease and its response to treatments.
Studies of the microbiome in the human gut focus mainly on bacteria. Other microbes that are also present in the gut -- viruses, protists, archaea and fungi -- have been largely overlooked.
Polyacrylamide gel electrophoresis is a technique that allows high-resolution isolation of proteins separated from biological specimens.
Many life-threatening medical conditions, such as sepsis, which is triggered by blood-borne pathogens, cannot be detected accurately and quickly enough to initiate the right course of treatment.
New research finds caffeine consumed during pregnancy can change important brain pathways that could lead to behavioral problems later in life.
Breast cancer could be identified more precisely than existing methods using blood specimens and exclusive proteomics-based technology.
Immediately after a traumatic brain injury and as long as one year later, there are increased levels of immune cells called ILCs in the brain promoting inflammation, which can worsen brain damage, scientists report.
A world-first discovery by researchers at Monash University and The University of Queensland could lead to faster and more effective treatments for chronic health complications, such as cardiovascular disease and cancer, with 'fluorescent' in vivo biosensors.
The study concludes that vegan diet has a broad effect on children's metabolism. Serum biomarker levels for vitamins A and D, cholesterol forms and essential amino acids were significantly lower in children on vegan diet compared to age-adjusted omnivores.
Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the body's immune response.
The abundant presence of an enzyme known as low molecular weight protein tyrosine phosphatase (LMWPTP) in tumor cells has long been considered an indicator of cancer aggressiveness and metastatic potential.
Proteogenomic studies may provide a better understanding of how to match cancer patients with an effective treatment for their specific cancer.
According to a research team headed by the University of Connecticut Health, a sugar-binding protein could drive terrible inflammation and worsen sepsis—a disease that kills over 270,000 individuals per year in the United States alone.
Companies like agrochemicals must check extensively for possible toxicity when they develop new products, before they can obtain regulatory approval.
Systemic sclerosis is an autoimmune disease associated with inflammation and fibrosis, or scarring, that affects organs including the skin, heart, kidney and lungs.
Infrared analyses of neuronal proteins provide information on molecular changes in patients with ALS. This helps to verify their diagnosis.