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Extraoral Bitter Taste Receptors Serve as Endogenous Sensors for Bile Acids

Taste receptors for bitter substances are not only observed on the tongue but also on cells outside of the oral cavity.

5 Jul 2023

Genetically Modified iPS Cell Applications for Fabry Disease

iPS cells have had a significant impact on biology and medicine, and they are expected to increase regenerative medicine. Clinical trials with various cell types derived from iPS cells have been performed since 2014 when a sheet of retinal pigment epithelial cells obtained from iPS cells was transplanted into patients with age-related macular degeneration.

4 Jul 2023

Ancient Virus-Like Transposons Found to Mediate Horizontal Gene Transfer in Worms

Scientists have known for decades that genes can be transferred from one species to another, both in animals and plants.

30 Jun 2023

Water Fasting Offers Short-Term Weight Loss, But No Long-Term Benefits

Water fasts -; where people consume nothing but water for several days -; might help you lose weight, but it's unclear how long you'll keep it off, according to research from the University of Illinois Chicago.

30 Jun 2023

Understanding Mammary Biology That May Help Find Therapeutic Targets for Breast Cancer

A new study led by researchers at The University of Texas MD Anderson Cancer, University of California, Irvine and Baylor College of Medicine has created the world's largest and most comprehensive map of normal breast tissue, providing an unprecedented understanding of mammary biology that may help identify therapeutic targets for diseases such as breast cancer.

29 Jun 2023

Cell Fate Conversion Plays Crucial Role in Cancer Research

Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz Association in Berlin and the Centre for Genomic Regulation (CRG) in Barcelona have discovered how cells speed changes to their identity known as “cell fate conversion.”

28 Jun 2023

Immune Deficits in Space are Temporary

An increase in proof has been found that astronauts are highly vulnerable to infections while in space. For instance, astronauts on board the International Space Station (ISS) generally suffer from skin rashes, and also respiratory and non-respiratory diseases.

23 Jun 2023

Elaborate 3D Structures of DNA That Mimics Protein Functions

According to a study from scientists at Weill Cornell Medicine and the National Heart, Lung, and Blood Institute, a division of the National Institutes of Health, DNA can imitate protein activities by folding into complex, three-dimensional structures.

22 Jun 2023

Newly Found Disease Links Disruptions of Blood Formation, Immune System and Inflammation

In the quest to find the origin of the puzzling symptoms in four children, researchers from St. Anna Children's Cancer Research Institute, the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences (ÖAW), and the Medical University of Vienna have discovered a completely new disease, linking disruptions of blood formation, the immune system, and inflammation.

22 Jun 2023

First Brain Atlas of Dwarf Cuttlefish

Anything with three hearts, blue blood and skin that can change colors like a display in Times Square is likely to turn heads.

21 Jun 2023

Using Enzyme Inhibitors to Assess the Potential for Antimicrobial Resistance

Early tests revealed that MK-3402, an experimental metallo-beta-lactamase inhibitor, was well tolerated after administration to healthy individuals.

19 Jun 2023

A New Class of Molecular Sensor Prevents Parasite Replication and Transmission

Malaria continues to be a serious public health issue, especially in sub-Saharan Africa, with almost 250 million cases per year and 621,000 fatalities.

19 Jun 2023

Microglial Cells Serve as a Stable Viral Reservoir for Latent HIV

Human immunodeficiency virus-1 (HIV) introduces a copy of its DNA into human immune cells as part of its life cycle. Some of these newly infected immune cells can subsequently enter an inactive, latent state for an extended length of time, which is known as HIV latency.

19 Jun 2023

Fungal Invasion Threatens Amphibian Biodiversity in North America

According to recent studies, the amphibian biodiversity could suffer greatly if the fungus infection Batrachochytrium salamandrivorans (Bsal) were introduced to North America.

15 Jun 2023

New Data Shows Gene Expression at Different Stages of Pregnancy

While the exterior features of a woman can alter throughout pregnancy, scientists are surprisingly ignorant about the interior biological changes that take place.

14 Jun 2023

Study Links Timing of Childhood Adversity With Epigenetic Patterns in Adolescents

Childhood adversity-;circumstances that threaten to a child's physical or psychological well-being--has long been associated with poorer physical and mental health throughout life, such as greater risks of developing cardiac disease, cancer, or depression.

14 Jun 2023