CRISPR News and Research

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In the late 1980s and mid-1990s, genomes of diverse lineages of bacteria and archaea (the latter representing a domain of single-celled prokaryotic microorganisms) revealed clusters of regularly interspaced short palindromic repeats, known today under the abbreviation CRISPR. Later it was found that these repeat sequences (previously considered disparate) share a common set of features.

New DNA-cutting tool could advance gene editing for novel treatments

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell's genome, according to a new study by UC San Francisco scientists.

21 Oct 2020

Study explores the impact of microbial immune diversity on dynamics of host-virus interactions

CRISPR-Cas serves as a key driving force of strain diversity in host-virus systems during an evolutionary fight between the host and virus.

21 Oct 2020

CRISPR platform can accelerate potential treatment targets for SARS-CoV-2

Synthego has provided multiple CRISPR-based engineered cell lines to speed up the analysis of promising treatment targets for SARS-CoV-2.

19 Oct 2020

Using CRISPR/Cas9 technology in trees for a bio-based economy

Researchers led by prof. Wout Boerjan (VIB-UGent Center for Plant Systems Biology) have discovered a way to stably finetune the amount of lignin in poplar by applying CRISPR/Cas9 technology.

7 Oct 2020

Researchers map genetic networks controlling human regulatory T cell identity

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed.

5 Oct 2020

Study may help develop new immunotherapies for different types of tumors

A team of researchers have plotted the genes that enable cancer cells to avoid being destroyed by the immune system.

25 Sep 2020

Researchers develop new tools that control the balance of genetic inheritance

In the last 10 years, scientists have designed a range of novel tools that regulate the balance of genetic inheritance.

22 Sep 2020

Researchers develop low-cost CRISPR method to detect SARS-CoV-2

In March 2020, scientists started to design a new, cost-efficient, CRISPR-based diagnostic platform to spot infectious diseases, such as SARS-CoV-2.

22 Sep 2020

CRISPR technique can improve the quality of barley grain

A group of plant researchers has demonstrated the ability to rapidly enhance the quality of barley grain using a genetic tool called CRISPR or gene editing.

21 Sep 2020

Researchers compare developed carriers for delivery of genome editing tools

Scientists made a comparison of their developed carriers for delivery of genome editing (GE) tools with other available analogs.

18 Sep 2020

Research finds gene family critical to unlocking vertebrate evolution

New University of Colorado Boulder-led research finds that the traits that make vertebrates distinct from invertebrates were made possible by the emergence of a new set of genes 500 million years ago, documenting an important episode in evolution where new genes played a significant role in the evolution of novel traits in vertebrates.

17 Sep 2020

Researchers identify the targets of immune rejection

Human pluripotent stem cells (hPSCs) show promise in regenerative medicine for how they lead to the fraction of every other type of cells in the body.

17 Sep 2020

Study pinpoints specific genes that cause ovarian cancer

High-grade serious ovarian carcinoma is the fifth major cause of cancer-associated deaths in women in the United States.

14 Sep 2020

Study shows how genetic variants affect gene regulation and contribute to disease risk

The multi-institutional Genotype-Tissue Expression (GTEx) Consortium has published its final series of studies, as part of a final-phase initiative.

14 Sep 2020

CRISPR in a Box: New educational gene editing tool kit

Introducing CRISPR in a Box™ - it's not a new crunchy cereal or the latest snack - it's an educational tool kit consisting of state-of-the-science gene editing technology that could be coming to a school near you.

10 Sep 2020

Novel tool helps select the best gene-editing option

Scientists have improved one of the biggest scientific advancement of the past decade.

10 Sep 2020

Study reveals gene that provides resistance to tomatoes from bacterial speck disease

Bacterial speck disease, which reduces both fruit yield and quality, has been a growing problem in tomatoes over the last five years.

3 Sep 2020

Researchers develop new gene therapy for congenital blindness

Retinitis pigmentosa is the most prevalent form of congenital blindness. Using a retinitis pigmentosa mouse model, researchers from Ludwig-Maximilians Universitaet (LMU) in Munich have now shown that targeted activation of genes of similar function can compensate for the primary defect.

3 Sep 2020

New method shows promise for treating diabetes and obesity

Obesity, the leading cause of type 2 diabetes and chronic illnesses, will collectively kill more people around the world in 2020 than COVID-19 coronavirus.

1 Sep 2020

New method accurately detects single gene mutation in a pool of 10,000 cells

Rare genetic mutations occurring in cells cannot be detected by existing sequencing techniques because these methods do not have the required sensitivity.

1 Sep 2020