Cancer News and Research

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Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body.

Unveiling the Role of Foxp3 in Shaping Chromatin Architecture of Regulatory T Cells

Regulatory T cells, or Tregs, represent a specialized class of immune cells dedicated to quelling immune responses and safeguarding the body against self-attack.

7 Nov 2023

Epidemiology and Genetic Underpinnings of Clonal Hematopoiesis

A comprehensive new study from deCODE genetics, a subsidiary of Amgen, published today in Nature Genetics, provides insights into the epidemiology and somatic and germline genetics of clonal hematopoiesis.

7 Nov 2023

Epigenetic Changes Drive Cancer Development

Every cell makes its own proteins by accessing the genetic information on its genes. Changes in this information, called mutations, may ruin the function of the affected proteins.

7 Nov 2023

Researchers Enhance CAR-T Cell Therapy by Preventing T-Cell Exhaustion

CAR-T cell therapy is a last hope for many patients with blood, bone marrow or lymph gland cancer when other treatments such as chemotherapy are unsuccessful.

7 Nov 2023

Nucleotide Metabolite Controls DNA Repair and Cancer Sensitivity

Scientists have unraveled the mechanism by which a particular metabolite regulates DNA repair activity and the susceptibility of tissues to cancer treatment.

3 Nov 2023

Exploring Z-RNA’s Role in Immune Response

Quentin Vicens, an Assistant Professor of Biology and Biochemistry at the University of Houston, has been granted $1.2 million by the National Institute of General Medical Sciences to investigate the enigmatic Z-RNA structure found within human cells.

3 Nov 2023

Research Reveals How Gut Bacteria Influence Distant Organs Through Oxytocin Signaling

The gut microbiome, a community of trillions of microbes living in the human intestines, has an increasing reputation for affecting not only gut health but also the health of organs distant from the gut.

3 Nov 2023

New Study Sheds Light on Evolution of Sex Differences in Animals

Researchers at the Francis Crick Institute and Heidelberg University in Germany have shown that sex differences in animals vary dramatically across species, organs and developmental stages, and evolve quickly at the gene level but slowly at the cell type level.

3 Nov 2023

Prime Editing and Base Editing Could Revolutionize Treatment for Phenylketonuria

Phenylketonuria (PKU) is a rare newborn genetic disease that impacts between 1 in 10,000 to 1 in 20,000 people, depending on the individuals' genetic ancestry. PKU causes an amino acid-;called phenylalanine (Phe)-;to build up in the bloodstream.

3 Nov 2023

New LoCKAmp Device Delivers Lab-Quality COVID Test Results in Just 3 Minutes

A virus diagnosis device that gives lab-quality results within just three minutes has been invented by engineers at the University of Bath, who describe it as the 'world's fastest Covid test'.

3 Nov 2023

Study Identifies Risk Genes and Regulatory Variants for Colorectal Cancer by Integrating Multi-Omics Data

This study was led by Prof. Xiao-Ping Miao' team from the School of Public Health, Wuhan University, in collaboration with Prof. Shaokai Zhang from the Henan Cancer Hospital.

2 Nov 2023

Scientists Unlock the Structure of Vesicular Monoamine Transporter 2

Neurons talk to each other using chemical signals called neurotransmitters. Scientists at St. Jude Children's Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter 2 (VMAT2), a key component of neuronal communication.

2 Nov 2023

Exploring the Role of Extracellular Vesicles in Cellular Communication

A research project, jointly conducted by scientists affiliated with the Germans Trias i Pujol Research Institute, has uncovered the potential advantages of employing an agarose spot migration assay for assessing the capacity of extracellular vesicles to attract neighboring cells within a controlled setting.

1 Nov 2023

DNA’s Role in Glioblastoma: Insights from Umeå University’s Research

A groundbreaking research conducted at Umeå University in Sweden has revealed that the three-dimensional arrangement of DNA can impact the development of aggressive brain cancer, glioblastoma.

1 Nov 2023

Novel Activation Mechanism for First Identified Oncogene

In the late 1970s, the link between the c-Src gene and cancer was unveiled, marking the identification of the inaugural oncogene.

1 Nov 2023

Targeting eIF4A with Zotatifin: A Promising Strategy for TNBC Treatment

Enhancing treatment options for triple-negative breast cancer (TNBC), a highly aggressive tumor with a grim prognosis and limited therapeutic possibilities has proven to be a formidable challenge.

31 Oct 2023

New Modular Nanoparticle Technology Opens the Door to a Variety of Therapeutic Approaches

Engineers at the University of California San Diego have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins.

31 Oct 2023

Philanthropic Partnership Unlocks £32 Million for the Future of Best-in-Class UK Biobank

Former CEO and Chairman of Google Eric Schmidt, and Ken Griffin, founder and CEO of Citadel and founder of Griffin Catalyst, are today (Monday 30 October) being announced as the first members of a new consortium that will shape the future of the best-in-class UK Biobank.

31 Oct 2023

New £100 Million Fund to Capitalise on AI’s Game-Changing Potential in Life Sciences and Healthcare

A new mission announced by the Prime Minister will accelerate the use of AI in life sciences to tackle the biggest health challenges of our generation.

30 Oct 2023

ISB Researchers Discover Genetic Key to T Cell Development

T cells are soldiers on the front lines of the human immune system. They are responsible for many important roles, including attacking viral- or bacterial-infected cells and certain cancer cells, and immunological memory – remembering the specific pathogens or the cancer signatures that originally trigger T cells.

26 Oct 2023

Cancer News and Research

Unveiling the Role of Foxp3 in Shaping Chromatin Architecture of Regulatory T Cells

Epidemiology and Genetic Underpinnings of Clonal Hematopoiesis

Epigenetic Changes Drive Cancer Development

Researchers Enhance CAR-T Cell Therapy by Preventing T-Cell Exhaustion

Nucleotide Metabolite Controls DNA Repair and Cancer Sensitivity

Exploring Z-RNA’s Role in Immune Response

Research Reveals How Gut Bacteria Influence Distant Organs Through Oxytocin Signaling

New Study Sheds Light on Evolution of Sex Differences in Animals

Prime Editing and Base Editing Could Revolutionize Treatment for Phenylketonuria

New LoCKAmp Device Delivers Lab-Quality COVID Test Results in Just 3 Minutes

Study Identifies Risk Genes and Regulatory Variants for Colorectal Cancer by Integrating Multi-Omics Data

Scientists Unlock the Structure of Vesicular Monoamine Transporter 2

Exploring the Role of Extracellular Vesicles in Cellular Communication

DNA’s Role in Glioblastoma: Insights from Umeå University’s Research

Novel Activation Mechanism for First Identified Oncogene

Targeting eIF4A with Zotatifin: A Promising Strategy for TNBC Treatment

New Modular Nanoparticle Technology Opens the Door to a Variety of Therapeutic Approaches

Philanthropic Partnership Unlocks £32 Million for the Future of Best-in-Class UK Biobank

New £100 Million Fund to Capitalise on AI’s Game-Changing Potential in Life Sciences and Healthcare

ISB Researchers Discover Genetic Key to T Cell Development

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