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Genetic editing tools stop the spread of Culex mosquitoes

Since the onset of the CRISPR genetic editing revolution, scientists have been working to leverage the technology in the development of gene drives that target pathogen-spreading mosquitoes such as Anopheles and Aedes species, which spread malaria, dengue and other life-threatening diseases.

From UC San Diego 31 May 2021

New software tool detects, evaluates, and quantifies off-target editing activity

CRISPR technology enables researchers to edit genomes by modifying DNA sequences and hence gene function.

27 May 2021

New, patented method helps drugs to easily enter the cells

A new technique known as Progressive Mechanoporation allows genes or drugs to enter cells by mechanically disrupting cell membranes for a brief period.

13 May 2021

Highly efficient method to identify the genetic “switches” that control gene expression

Scientists have created a high-throughput method to help explain and regulate gene expression for the treatment of diseases like beta-thalassemia and sickle cell disease.

7 May 2021

New therapeutic target for patients with acute myeloid leukemia

According to a new study, targeting a pathway that is critical for the survival of some cases of acute myeloid leukemia could open up a new therapeutic route for patients.

3 May 2021

New gene therapy could help treat Duchenne muscular dystrophy

Researchers from UT Southwestern used a new kind of gene therapy to successfully treat mice with Duchenne muscular dystrophy (DMD), distinctively employing CRISPR-Cas9-based tools to restore a large section of the dystrophin protein missing in several DMD patients.

3 May 2021

New gene editing tool helps analyze the mysterious quirk of bacteria

While the CRISPR-Cas9 gene editing system has become the poster child for innovation in synthetic biology, it has some major limitations.

3 May 2021

New computer algorithm helps identify tumors with 'mismatch repair deficiencies'

A new way to identify tumors that could be sensitive to particular immunotherapies has been developed using data from thousands of NHS cancer patient samples sequenced through the 100,000 Genomes Project.

27 Apr 2021

New gene editing approach bypasses disease-causing mutations

A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases.

From Penn State University 22 Apr 2021

Eucalyptus can be genetically modified to prevent from invading native ecosystems

Eucalyptus, a pest-resistant evergreen valued for its hardy lumber and wellness-promoting oil, can be genetically modified not to reproduce sexually, a key step toward preventing the global tree plantation staple from invading native ecosystems.

8 Apr 2021

Japanese consumers have more negative opinions about gene-editing of livestock, survey finds

A statistically rigorous survey of Japanese consumers has found that they have more negative opinions about the use of new gene-editing techniques on livestock than they do about use of the same technologies on vegetables.

7 Apr 2021

New CRISPR-SNP-Chip technology detects single-point mutations without amplification

The CRISPR-Chip technology was first introduced in 2019 by Dr. Kiana Aran, an Assistant Professor at Keck Graduate Institute (KGI).

6 Apr 2021

Six novel CRISPR-Cas12a variants expand genome engineering in plants

Yiping Qi continues to create new genome editing and engineering in plants, with the ultimate objective of enhancing the efficiency of food production.

31 Mar 2021

Improved version of CRISPR/Cas9 tool helps study the interaction of various genes

Researchers have used an upgraded version of the gene-editing tool, CRISPR/Cas9, to knock out up to 12 genes in plants in just one go.

23 Mar 2021

New “genome scalpel” can rapidly trim microalgal genomes

A single-celled alga removes non-essential pieces by undergoing genome surgery.

18 Mar 2021

New gene editor could help treat genetic disorders caused by single-nucleotide mutations

Scientists have created a CRISPR-based gene editor named C-to-G Base Editor (CGBE) that can correct mutations responsible for genetic disorders.

15 Mar 2021

Optimized nano-micelles can induce efficient genome editing in mouse brain

A research team has reported that improved nano-micelles can trigger efficient genome editing in the mouse brain.

15 Mar 2021

New gene-drive technologies can help control crop pests

Robust new genetic engineering techniques have given researchers the ability to transform many sectors of global urgency.

From UC San Diego 8 Mar 2021

CRISPR-Cas9 can safeguard future crops under stress from variable climate conditions

Gene editing technology will play a vital role in climate-proofing future crops to protect global food supplies, according to scientists at The University of Queensland.

2 Mar 2021

New function of regulatory gene may lead to more productive plant varieties

A team of researchers has confirmed that the SUPERMAN gene also establishes the number of flowers in leguminous plants.

1 Mar 2021

Cas9 News and Research

Genetic editing tools stop the spread of Culex mosquitoes

New software tool detects, evaluates, and quantifies off-target editing activity

New, patented method helps drugs to easily enter the cells

Highly efficient method to identify the genetic “switches” that control gene expression

New therapeutic target for patients with acute myeloid leukemia

New gene therapy could help treat Duchenne muscular dystrophy

New gene editing tool helps analyze the mysterious quirk of bacteria

New computer algorithm helps identify tumors with 'mismatch repair deficiencies'

New gene editing approach bypasses disease-causing mutations

Eucalyptus can be genetically modified to prevent from invading native ecosystems

Japanese consumers have more negative opinions about gene-editing of livestock, survey finds

New CRISPR-SNP-Chip technology detects single-point mutations without amplification

Six novel CRISPR-Cas12a variants expand genome engineering in plants

Improved version of CRISPR/Cas9 tool helps study the interaction of various genes

New “genome scalpel” can rapidly trim microalgal genomes

New gene editor could help treat genetic disorders caused by single-nucleotide mutations

Optimized nano-micelles can induce efficient genome editing in mouse brain

New gene-drive technologies can help control crop pests

CRISPR-Cas9 can safeguard future crops under stress from variable climate conditions

New function of regulatory gene may lead to more productive plant varieties

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