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Intracellular microbiota promote cell survival during tumor progression

Bacteria promote cancer metastasis by bolstering the strength of host cells against mechanical stress in the bloodstream, promoting cell survival during tumor progression, researchers report April 7th in the journal Cell.

8 Apr 2022

New scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes

A Mount Sinai-led team has developed a reproducible and scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs)-;cells that support heart muscle contraction, generated in the lab from human stem cell lines-;which researchers say will improve approaches for disease modeling, regenerative therapies, and drug testing.

8 Apr 2022

Understanding the role of ORF8 viral gene in COVID-19 infection and outcomes

A research team led by Jae Jung, PhD, Director of Cleveland Clinic's Global Center for Pathogen & Human Health Research, has uncovered the critical role a viral gene, ORF8, plays in infection and disease outcomes of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19.

8 Apr 2022

Researchers identify a large number of specific genes associated with schizophrenia

What is the role of genetics in schizophrenia? To address this question, an international group of researchers led by Charité – Universitätsmedizin Berlin and Cardiff University developed and conducted the largest-ever genetic study on schizophrenia.

8 Apr 2022

Primordial germ cell-like cells produced from stem cells undergo gametogenesis to yield normal offspring

Primordial germ cell-like cells (PGCLCs), generated in vitro from the stem cells of rats, undergo gametogenesis in vivo and yield normal rat offspring, a new study demonstrates.

8 Apr 2022

New technique helps rewind the cellular biological clock by around 30 years

Research from the Babraham Institute has developed a method to 'time jump' human skin cells by 30 years, turning back the aging clock for cells without losing their specialized function.

8 Apr 2022

Scientists identify factors that regulate the development of brain cells in a specific order

Researchers have identified the complete series of 10 factors that regulate the development of brain cell types in the visual system of fruit flies-; including in what order these neurons develop.

From New York University (NYU) 7 Apr 2022

Curcumin released from magnetic hydrogels can aid in vascular regeneration

A finding by UC Riverside bioengineers could hasten development of lab-grown blood vessels and other tissues to replace and regenerate damaged tissues in human patients.

7 Apr 2022

Combining organoids and microfluidics to study how the immune system responds to hepatitis C

A vaccine for hepatitis C has eluded scientists for more than 30 years, for several reasons. For one, the virus that causes the disease comes in many genetic forms, complicating the creation of a widely effective vaccine.

7 Apr 2022

New technique for better visualizing the CNS fibroblasts

The central nervous system (CNS) consists of several types of cells having varied specialized functions.

7 Apr 2022

A mitochondrial uncoupler prevents sarcopenic obesity in elderly mice

A recently discovered chemical compound helped elderly mice with obesity lose fat and weight, add muscle and strength, reduce age-related inflammation and increase physical activity, a new study shows.

7 Apr 2022

Specialist assay kits and microplates for cancer research

Porvair Sciences will exhibit its latest assay kits and microplates for cancer and life science research at the American Association for Cancer Research (AACR) meeting in New Orleans, USA from the 8th – 13th April 2022.

From Porvair Sciences Limited 7 Apr 2022

Newborn cells in patients with epilepsy, likely to provide a potential treatment

According to a study headed by researchers from USC Stem Cell and the USC Neurorestoration Center, adults may recover at least some of what they have lost by producing new brain cells, and this process is profoundly modified in patients with long-term epilepsy.

7 Apr 2022

Researchers discover how an “accordion effect” is vital for switching off genes

In a study that changes the fundamentals of what researchers know about gene silencing, WEHI researchers demonstrated how an “accordion effect” is key to switching off genes.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 7 Apr 2022

Transposons are a potential antibiotic resistance, a study reveals

According to biomedical engineers at Duke University, the physical mechanism that enables high doses of antibiotics to encourage the transmission of antibiotic resistance across bacteria is now identified.

7 Apr 2022

Study sheds light on genetic causes of Alzheimer’s disease and other dementias

If we want to enhance our knowledge and treatment of Alzheimer’s disease, we need to identify genetic risk factors.

7 Apr 2022

Study discovers links between DNA methylation and gene expression in children

A new study headed by ISGlobal, an organization financed by “Ia Caixa” Foundation, finds links between DNA methylation patterns and gene expression levels in blood samples from youngsters.

7 Apr 2022

Breakthrough discovery provides a desirable drug target to tackle metabolic diseases

In a breakthrough discovery, scientists from The University of Texas Health Science Center at San Antonio today reported that inhibiting a liver enzyme in obese mice decreased the rodents' appetite, increased energy expenditure in adipose (fat) tissues and resulted in weight loss.

6 Apr 2022

Certain RNA molecules may serve as markers of cellular stress in different diseases

The body's ability to respond to various types of stress is essential for maintaining health, and failure of such adaptive stress responses can trigger or worsen numerous diseases.

6 Apr 2022

Single-cell RNA sequencing reveals temporal patterning network in Drosophila medulla neuroblasts

The nervous system is made up of diverse cells that arise from progenitors in a specific time-dependent pattern.

6 Apr 2022

Cell News and Research

Intracellular microbiota promote cell survival during tumor progression

New scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes

Understanding the role of ORF8 viral gene in COVID-19 infection and outcomes

Researchers identify a large number of specific genes associated with schizophrenia

Primordial germ cell-like cells produced from stem cells undergo gametogenesis to yield normal offspring

New technique helps rewind the cellular biological clock by around 30 years

Scientists identify factors that regulate the development of brain cells in a specific order

Curcumin released from magnetic hydrogels can aid in vascular regeneration

Combining organoids and microfluidics to study how the immune system responds to hepatitis C

New technique for better visualizing the CNS fibroblasts

A mitochondrial uncoupler prevents sarcopenic obesity in elderly mice

Specialist assay kits and microplates for cancer research

Newborn cells in patients with epilepsy, likely to provide a potential treatment

Researchers discover how an “accordion effect” is vital for switching off genes

Transposons are a potential antibiotic resistance, a study reveals

Study sheds light on genetic causes of Alzheimer’s disease and other dementias

Study discovers links between DNA methylation and gene expression in children

Breakthrough discovery provides a desirable drug target to tackle metabolic diseases

Certain RNA molecules may serve as markers of cellular stress in different diseases

Single-cell RNA sequencing reveals temporal patterning network in Drosophila medulla neuroblasts

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