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Microbes hindering cancer therapy seem to play a bigger role than helpful ones

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

1 Mar 2022

US research reveals the role of Heparan Sulfate in obesity

AMSBIO reports how researchers at the Washington University School of Medicine (St. Louis, USA) have used their 10E4 Heparan Sulfate (HS) antibody in pioneering obesity research to quantify the role of HS in the process of intercellular mitochondria transfer to macrophages.

From AMS Biotechnology 1 Mar 2022

Looking at protein activity gives a complete picture of leukemia's weaknesses

Blocking a protein chain reaction makes childhood leukemia cells more sensitive to an existing targeted treatment, a new study shows.

28 Feb 2022

Scientists reveal the spectacular structure of C.difficile's protective armor

The spectacular structure of the protective armor of superbug C.difficile has been revealed for the first time showing the close-knit yet flexible outer layer – like chain mail.

From Newcastle University 28 Feb 2022

Researchers discover new stem cell population that closely matches existing human stem cells

Reik lab researchers’ recent discovery describes a new subpopulation of human embryonic stem cells that closely match the cells present at the genomic “wake up call” of the 8-cell embryo stage in humans.

28 Feb 2022

Macrophages restore normal functions when transported back to the body, says research

New research shows that some immune cells could reinstate their regular functions when they are introduced back into the body.

28 Feb 2022

Study investigates the relationship between healthy tissue repair and cancer growth

Scientists at the Francis Crick Institute have revealed how a mechanism involved in the regeneration of tissue can help the spread of cancer.

28 Feb 2022

Scientists elucidate mechanism that causes treatment resistance in aggressive pancreatic cancer

Drug resistance is a major obstacle in the treatment of cancers. In an aggressive type of pancreatic cancer, for instance, drug resistance is associated with the suppression of programmed cell death, which results in the uncontrolled growth of cancer cells.

25 Feb 2022

Chlamydia and HPV co-infection causes a unique cellular reprogramming, study shows

Infections with several pathogens simultaneously increase the risk of cervical cancer—these results from a study conducted on artificial 3D tissue models.

25 Feb 2022

Researchers create a regulatory map of zebrafish genome

The zebrafish is an important model organism for studying things like genetic diseases. A regulatory map of its genome has been successfully created using high-throughput experiments and AI methods, a team led by Uwe Ohler now reports in Cell Genomics and Nature Machine Intelligence.

25 Feb 2022

Researchers gain better understanding of the fast signaling dynamics in stem cells

Divide, differentiate or die? Making decisions at the right time and place is what defines a cell's behavior and is particularly critical for stem cells of an developing organisms.

From The Max Planck Institute 25 Feb 2022

MIT chemists develop a new way to synthesize potential antibiotic

Chemists at MIT have developed a novel way to synthesize himastatin, a natural compound that has shown potential as an antibiotic.

25 Feb 2022

Single Use Support brings cell & gene therapy expert Katy Spink on board

Katherine (Katy) Spink has become a member of Single Use Support’s Board of Directors. Her many years of expertise in cell & gene therapy consulting will enrich the companies’ focus on innovating solutions for advanced therapies.

From Single Use Support GmbH 25 Feb 2022

Genetics serves a vital role in the way human bodies respond to vaccination and boosters, says study

According to a new study headed by University of Michigan researchers, genetics serve a vital role in the way human bodies respond to vaccinations and booster shots.

25 Feb 2022

Central signaling pathway likely to help reduce the progression of autoimmune disorders

When the immune system fails and assaults the body’s own components, autoimmune disorders develop.

25 Feb 2022

Researchers analyze how RNA molecules control the repair of damaged DNA in cancer cells

A new study from Sweden’s Karolinska Institute demonstrates how some RNA molecules regulate the repair of damaged DNA in cancer cells.

25 Feb 2022

A cryptic molecule can awaken killer viruses from their slumber

Some gut bacteria have a spooky superpower: they can reanimate dormant viruses lurking within other microbes.

24 Feb 2022

Study identifies a new cancer cell state related to poor treatment response in ovarian cancer patients

The prognosis for ovarian cancer patients is grim: less than half of high-grade serous ovarian cancer (HGSC) patients survive past five years from diagnosis. Initially, the tumors typically respond well to chemotherapy but become resistant after repeated treatments, enabling the cancer to regrow.

24 Feb 2022

New technique uses microscopic magnetic particles to remotely activate brain cells

Scientists at UCL have developed a new technique that uses microscopic magnetic particles to remotely activate brain cells; researchers say the discovery in rats could potentially lead to the development of a new class of non-invasive therapies for neurological disorders.

From University College London 24 Feb 2022

New study uncovers potential driver of Parkinson’s disease

Parkinson's disease may be driven in part by cell stress-related biochemical events that disrupt a key cellular cleanup system, leading to the spread of harmful protein aggregates in the brain, according to a new study from scientists at Scripps Research.

24 Feb 2022

Cell News and Research

Microbes hindering cancer therapy seem to play a bigger role than helpful ones

US research reveals the role of Heparan Sulfate in obesity

Looking at protein activity gives a complete picture of leukemia's weaknesses

Scientists reveal the spectacular structure of C.difficile's protective armor

Researchers discover new stem cell population that closely matches existing human stem cells

Macrophages restore normal functions when transported back to the body, says research

Study investigates the relationship between healthy tissue repair and cancer growth

Scientists elucidate mechanism that causes treatment resistance in aggressive pancreatic cancer

Chlamydia and HPV co-infection causes a unique cellular reprogramming, study shows

Researchers create a regulatory map of zebrafish genome

Researchers gain better understanding of the fast signaling dynamics in stem cells

MIT chemists develop a new way to synthesize potential antibiotic

Single Use Support brings cell & gene therapy expert Katy Spink on board

Genetics serves a vital role in the way human bodies respond to vaccination and boosters, says study

Central signaling pathway likely to help reduce the progression of autoimmune disorders

Researchers analyze how RNA molecules control the repair of damaged DNA in cancer cells

A cryptic molecule can awaken killer viruses from their slumber

Study identifies a new cancer cell state related to poor treatment response in ovarian cancer patients

New technique uses microscopic magnetic particles to remotely activate brain cells

New study uncovers potential driver of Parkinson’s disease

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