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Study shows mothers provide necessary microbes to babies born via cesarean

Can newborns delivered by cesarean surgery lack vital microbes? Recent data suggests that “no” could be the answer. Mothers are able to transmit bacteria to their babies through alternative, compensating channels, according to research published in the journal Cell Host & Microbe on March 8th, 2023.

10 Mar 2023

Novel protein complex plays a significant role in RNA protection

Two proteins help in protecting and stabilizing RNA as it travels through the cell carrying muscle-forming code. Studying this RNA-stabilizing complex further may have ramifications for muscle recovery and disease treatment.

10 Mar 2023

Potential therapeutic can synergize with existing drugs to effectively destroy leukemia cells

A team of researchers has discovered a potential therapeutic that can synergize with existing drugs to more effectively kill certain leukemia cells.

9 Mar 2023

Pathogenic fungus binds to a human protein to escape elimination from lung cells

The pathogenic fungus Aspergillus fumigatus escapes elimination from surface cells of the human lung by binding to a human protein.

9 Mar 2023

Deeper understanding of T-cell responses may lead to better, more personalized immunotherapies

For the first time, a research team has identified and analyzed the steps by which immune cells "see" and respond to cancer cells, providing insights into reasons some treatments may be effective for certain patients but not others.

9 Mar 2023

Scientists shed new light on aging processes in the brain

Scientists from the Trinity Biomedical Sciences Institute (TBSI) have shed new light on aging processes in the brain.

9 Mar 2023

Study shows link between a mitochondrial metabolite and activation of inflammatory response

A new study shows for the first time a connection between a mitochondrial metabolite and the activation of an inflammatory response.

9 Mar 2023

Small group of airway neurons plays a key role in alerting the brain about infection

A new study led by researchers at Harvard Medical School illuminates how the brain becomes aware that there is an infection in the body.

9 Mar 2023

“Bacterial suicide squad” recruits and activates innate and adaptive antitumor immune responses

Combining discoveries in cancer immunology with sophisticated genetic engineering, Columbia University researchers have created a sort of "bacterial suicide squad" that targets tumors, attracting the host's own immune cells to the cancer to destroy it. The new work, published today in Science Advances, marks a major step forward in efforts to enlist non-pathogenic bacteria to combat cancer.

9 Mar 2023

Monitoring the development and maturation of cardiomyocytes using tissue-embedded devices

Research in animal models has demonstrated that stem-cell derived heart tissues have promising potential for therapeutic applications to treat cardiac disease. But before such therapies are viable and safe for use in humans, scientists must first precisely understand on the cellular and molecular levels which factors are necessary for implanted stem-cell derived heart cells to properly grow and integrate in three dimensions within surrounding tissue.

9 Mar 2023

Study findings reveal drug development possibilities for brain diseases

Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease, a reflection of the growing recognition that immune processes play a key role in driving the brain damage that leads to confusion, memory loss and other debilitating symptoms.

9 Mar 2023

Scientists reveal mechanisms behind oxygen toxicity

When it comes to oxygen, you can have too much of a good thing. Breathing air that contains higher levels of oxygen than the usual 21 percent found in Earth's atmosphere can cause organ damage, seizures, and even death in people and animals, particularly if it's in excess of the body's oxygen needs. Until now, however, scientists have mostly speculated about the mechanisms behind this phenomenon, known as oxygen toxicity, or hyperoxia.

9 Mar 2023

Liver-produced hormone protects mice against the harmful effects of intoxication

A shot of a liver-produced hormone called FGF21 sobered up mice that had passed out from alcohol, allowing them to regain consciousness and coordination much faster than those that didn't receive this treatment, UT Southwestern researchers report in a new study.

8 Mar 2023

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Short exposure to altered gravity does not alter leukocyte immunophenotyping and functional capacity

Space travel has always tested the human body by the effects of the new conditions of altered gravity on biological systems.

8 Mar 2023

LDL-mediated nanoparticle drug delivery could potentially circumvent high-grade gliomas

New research has shown that the blood vessels that feed aggressive brain tumors have receptors that could allow a new type of drug-containing nanoparticle to be used to starve the tumors of the energy they use to grow and spread, and also cause other disruptions to their adapted existence, even killing themselves.

8 Mar 2023

Discovery could establish an effective control environment for chromosome instability

A research team, affiliated with UNIST has unveiled a key factor involved in the DNA damage response (DDR), homologous recombination (HR) and DNA interstrand crosslink (ICL) repair.

8 Mar 2023

Analyzing microscopic chalk disks coccoliths formed by the marine algae

Under the guidance of Rutgers University, a research group learning about virus-host interactions of worldwide abundant and armor-plated marine algae, Emiliania huxleyi, has discovered that the circular and chalk plates produced by the algae have the potential to serve as catalysts for viral infection.

From Rutgers University 7 Mar 2023

An alternative option to treat ADCY5-related dyskinesia in patients

The asthma medication theophylline can be used to treat the movement disorder ADCY5-related dyskinesia. A recent study conducted by Martin Luther University Halle-Wittenberg (MLU), University Medicine Halle, and the University of Leipzig Medical Center demonstrated this.

7 Mar 2023

Researchers discover how specific mutation in a bacterium results in phage resistance

As antibacterial resistance continues to render obsolete the use of some antibiotics, some have turned to bacteria-killing viruses to treat acute infections as well as some chronic illnesses.

7 Mar 2023

Cell News and Research

Study shows mothers provide necessary microbes to babies born via cesarean

Novel protein complex plays a significant role in RNA protection

Potential therapeutic can synergize with existing drugs to effectively destroy leukemia cells

Pathogenic fungus binds to a human protein to escape elimination from lung cells

Deeper understanding of T-cell responses may lead to better, more personalized immunotherapies

Scientists shed new light on aging processes in the brain

Study shows link between a mitochondrial metabolite and activation of inflammatory response

Small group of airway neurons plays a key role in alerting the brain about infection

“Bacterial suicide squad” recruits and activates innate and adaptive antitumor immune responses

Monitoring the development and maturation of cardiomyocytes using tissue-embedded devices

Study findings reveal drug development possibilities for brain diseases

Scientists reveal mechanisms behind oxygen toxicity

Liver-produced hormone protects mice against the harmful effects of intoxication

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Short exposure to altered gravity does not alter leukocyte immunophenotyping and functional capacity

LDL-mediated nanoparticle drug delivery could potentially circumvent high-grade gliomas

Discovery could establish an effective control environment for chromosome instability

Analyzing microscopic chalk disks coccoliths formed by the marine algae

An alternative option to treat ADCY5-related dyskinesia in patients

Researchers discover how specific mutation in a bacterium results in phage resistance

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