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OTUD3 shows opposing effects in innate immunity to RNA and DNA viruses

The identification of pathogen-associated molecular patterns (PAMPs) by pattern-recognition receptors (PRRs) is the first step in initiating an immune response to viral infection.

13 Jun 2022

Study shows how probiotic bacteria may lower the risk of ER+ breast cancer

A new study presented at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga., suggests that probiotic bacteria may improve the anti-cancer actions of the breast cancer drug tamoxifen as well as other endocrine-targeted therapies, potentially lowering the risk of estrogen receptive positive (ER+) breast cancer.

13 Jun 2022

ZDHHC18-mediated MDH2 palmitoylation upholds mitochondrial respiration and boosts ovarian cancer malignancy

To drive anabolic processes, epithelial ovarian cancer (EOC) is heavily reliant on the tricarboxylic acid (TCA) cycle and oxidative phosphorylation.

13 Jun 2022

Researchers discover a new interferon-gamma receptor signaling pathway

The interferon-gamma receptor (IFNgR) signaling pathway has been identified to be crucial for the vulnerability of glioblastoma tumors to death by CAR T-cell immunotherapy, according to researchers at Massachusetts General Hospital (MGH).

10 Jun 2022

Researchers analyze and demonstrate how organelles divide into cells

The research, headed by Professor Michael Schrader of the University of Exeter, looked at peroxisome dynamics and discovered new ways for them to divide.

From University of Exeter 10 Jun 2022

Origin of chromatin in ancient microbes happened 1–2 billion years ago, study reveals

Nature’s storage solution originally emerged in ancient microbes living on Earth around one and two billion years ago, according to researchers at the Center for Genomic Regulation (CRG).

10 Jun 2022

Scientists discover that most synonymous mutations are strongly harmful

University of Michigan scientists reveal that most synonymous mutations are severely damaging in a study published in Nature that entailed genetic manipulation of yeast cells in the lab.

9 Jun 2022

Gene expression analysis helps identify genes that cause endocrine resistance in breast cancer

The most prevalent type of cancer detected in women is breast cancer (BC). BC is the second biggest cause of death among female cancer patients globally.

9 Jun 2022

Researchers determine small protein’s structure, likely to pave the way for advanced treatments

For the first time, researchers have deciphered the atomic structure of a protein that transports one of the body’s most vital neurotransmitters into neurons.

9 Jun 2022

Scientists identify a way to release the brakes on plants’ production of aromatic amino acids

Every day, plants around the world perform an invisible miracle. They take carbon dioxide from the air and, with the help of sunlight, turn it into countless chemicals essential to both plants and humans.

9 Jun 2022

Dietary modifications can lower symptoms of allergic reactions, a new study reveals

Micronutrient deficits can increase inflammation and make the immune system more susceptible to allergens. Iron deficiency indicates danger to immune cells and causes an excessive immunological response.

8 Jun 2022

Novel insights into how some bacteria evade antibiotics

Scientists have revealed how antibiotics can regress certain fast-growing bacteria. The research was published in the journal eLife on June 8th, 2022.

8 Jun 2022

Characterizing the genetic factors impacting the immune response in type 1 diabetes

A new study performed has offered better knowledge about how genetic factors tend to impact the immune response of the body in type 1 diabetes.

8 Jun 2022

Researchers use new technique to examine the composition of cell walls from young poplar trees

To optimize biomaterials for reliable, cost-effective paper production, building construction, and biofuel development, researchers often study the structure of plant cells using techniques such as freezing plant samples or placing them in a vacuum.

8 Jun 2022

Axol Bioscience introduces CiPA-validated human stem cell-derived ventricular cardiomyocytes to help improve drug discovery

Axol Bioscience Ltd. (Axol), an established provider of iPSC-derived cells, media, and characterization services for life science discovery, today announced that its human induced pluripotent stem cell (iPSC)-derived ventricular cardiomyocytes have undergone comprehensive in vitro pro-arrhythmia assay (CiPA) validation.

From Axol Bioscience Ltd 8 Jun 2022

Study provides new knowledge on the influence of membrane proteins on plant growth

Ubiquitin is a tiny regulatory protein that can be present in most eukaryotic cells. It is important for changing the function of other proteins, and it is especially important for protein breakdown and localization inside the cell. Ubiquitin regulates these actions through ubiquitination (attaching to and detaching from a target protein).

6 Jun 2022

Computational DNA droplet recognizes a specific combination of tumor biomarker microRNAs

The formation of aqueous droplets in macromolecules by liquid-liquid phase separation (or coacervation) is a popular topic in life sciences research. DNA is particularly interesting among the numerous macromolecules that form droplets because it is predictable and programmable, both of which are desirable properties in nanotechnology.

6 Jun 2022

Researchers analyze functional microglia to empower retinal organ

Professor Zi-Bing Jin is in charge of this research (Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, and Capital Medical University). He has spent the last decade working on retinal organoids, which can accurately mimic retinal development.

3 Jun 2022

Study describes the importance of the autoimmune response in bacteria

CRISPR has made headlines in recent years for its potential to help patients with conditions as diverse as blindness and sickle cell disease. However, bacteria were already using CRISPR as an immune system to combat viruses long before humans adopted it to combat genetic disorders.

3 Jun 2022

Study identifies the regulatory function of non-coding 7S RNA

In human cells, a non-coding RNA molecule controls mitochondrial gene expression, according to new research published in the journal Cell. The research is the result of a collaboration between Sweden’s University of Gothenburg and Karolinska Institutet, as well as Germany’s University of Cologne.

3 Jun 2022

Cell News and Research

OTUD3 shows opposing effects in innate immunity to RNA and DNA viruses

Study shows how probiotic bacteria may lower the risk of ER+ breast cancer

ZDHHC18-mediated MDH2 palmitoylation upholds mitochondrial respiration and boosts ovarian cancer malignancy

Researchers discover a new interferon-gamma receptor signaling pathway

Researchers analyze and demonstrate how organelles divide into cells

Origin of chromatin in ancient microbes happened 1–2 billion years ago, study reveals

Scientists discover that most synonymous mutations are strongly harmful

Gene expression analysis helps identify genes that cause endocrine resistance in breast cancer

Researchers determine small protein’s structure, likely to pave the way for advanced treatments

Scientists identify a way to release the brakes on plants’ production of aromatic amino acids

Dietary modifications can lower symptoms of allergic reactions, a new study reveals

Novel insights into how some bacteria evade antibiotics

Characterizing the genetic factors impacting the immune response in type 1 diabetes

Researchers use new technique to examine the composition of cell walls from young poplar trees

Axol Bioscience introduces CiPA-validated human stem cell-derived ventricular cardiomyocytes to help improve drug discovery

Study provides new knowledge on the influence of membrane proteins on plant growth

Computational DNA droplet recognizes a specific combination of tumor biomarker microRNAs

Researchers analyze functional microglia to empower retinal organ

Study describes the importance of the autoimmune response in bacteria

Study identifies the regulatory function of non-coding 7S RNA

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