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Protein TRBP's Regulatory Role in Immune Response to Viral Infections Uncovered

Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells.

22 Apr 2024

Unveiling Cannabinoid’s Potential for Treating Age-Related Brain Degeneration

Scientists at the Salk Institute observed the neuroprotective effects of cannabinol in fruit flies and discovered cannabinoid analogs that may prove to be promising future treatments for Parkinson's, Alzheimer's, and traumatic brain injury.

18 Apr 2024

KIT Researchers Uncover New Cell Type Responsible for Vascular Growth

Cardiovascular diseases, including stroke and myocardial infarction, are the world's leading causes of mortality, accounting for over 18 million deaths a year.

18 Apr 2024

Mapping Gene Signatures Unveils How Lewy Bodies Impact Brain Cells

A new study by scientists at Van Andel Institute provides an initial glimpse into the intricate molecular changes taking place in brain cells with Lewy bodies, crucial pathological markers of Parkinson’s disease and certain dementias.

17 Apr 2024

Newly discovered mechanism identified in the initial stages of Alzheimer's disease

Alzheimer's disease (AD) continues to be one of the most difficult and common neurodegenerative diseases, impacting millions of people globally.

16 Apr 2024

Precision Combination Therapy Better Controls High-Risk Subtypes of B-ALL in Mouse Models

Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between 30-50%.

9 Apr 2024

New Method Revolutionizes Assessment of Ferroptosis-Targeting Enzymes

New research could pave the way to develop cancer drugs targeting an enzyme that inhibits ferroptosis, a type of cell death.

8 Apr 2024

Study Reveals Insights into Evolution of Regulatory Proteins

New research from the University of Wisconsin–Madison decodes the evolutionary pathway of regulatory proteins, the molecules that help control gene expression.

1 Apr 2024

Researchers Identify RNA-Regulator Brat as Key Player in Restraining Tissue Regeneration

Some animals possess the remarkable ability to regenerate lost structures, exemplified by a lizard regrowing its tail.

20 Mar 2024

New Research Into the Impact of Microplastics and Nanoplastics on Human Health is Urgently Required Due to ‘Significant Threat’ to Human Health

A new metastudy published in Cambridge Prisms: Plastics by Cambridge University Press, has identified a body of evidence demonstrating the negative impact of microplastics and nanoplastics (MPs and NPs) on human health and identifying the limitations of current research.

20 Mar 2024

'lncREST' RNA Unveiled as Key Player in DNA Replication Stress Response

Researchers at Cima Universidad de Navarra have discovered that a ribonucleic acid that does not contain information to make proteins (long non-coding RNA) plays a crucial role in signalling and repairing errors in DNA replication during cell division.

5 Mar 2024

SOX17 Gene Identified as Critical for Immune Evasion in Early-Stage Colon Cancer

One of the immune system's primary roles is to detect and kill cells that have acquired cancerous mutations.

29 Feb 2024

The Hidden Link Between Cell Membrane Damage and Cellular Senescence Revealed

Researchers from the Okinawa Institute of Science and Technology (OIST) along with the researchers from University of Tokyo, Nagoya University, and Nagoya City University, found that disruption to the cell membrane accelerates cellular senescence or cell aging.

23 Feb 2024

Rare Lipid Identified as Key Driver of Ferroptosis

Columbia researchers have found that a rare type of lipid is a key driver of ferroptosis, a form of cell death discovered by Columbia professor Brent Stockwell.

16 Feb 2024

Unlocking RNA Secrets: New Method Exposes Gene Expression's Hidden Hurdles

A new study demonstrates that a method may identify, for the first time, the frequency and precise location of a molecular occurrence known as "backtracking" across the genetic material (genome) of any species.

12 Feb 2024

Imec's Microfluidics Chip Shows Promise in Cancer Immune Profiling

The first clinical validation of Imec's cell sort chip technology has been reported in Cells through a new collaboration between Imec and the KU Leuven Laboratory of Tumor Immunology and Immunotherapy.

6 Feb 2024

Study Unveils Dual Role of 7-DHC in Ferroptosis and Cancer Cell Survival

Cell death is fundamental to life and, thus, healthy aging. In the realm of cellular biology, ferroptosis (a form of programmed cell death) has emerged not only as a focal point of research for its potential in eliminating cancer cells, but also its role in a plethora of other diseases, including neurodegenerative diseases such as Alzheimer's disease, eye diseases such as Retinitis pigmentosa and age-related macular degeneration, as well as ischemia, cardiovascular disease, liver disease, acute kidney injury and inflammation.

2 Feb 2024

New Research Finds Placenta Cells May Lower Blood Pressure

Scientists from La Trobe University and the Hudson Institute have demonstrated that cells from placentas could have therapeutic benefits for patients suffering from high blood pressure.

1 Feb 2024

Bacteria's Immune System Enhances the Effect of Antibiotics Against Cholera Pathogen

Bacteria have an immune system that protects them against viruses known as bacteriophages. A research team from the Universities of Tübingen and Würzburg has now shown how this immune system enhances the effect of specific antibiotics against the cholera pathogen Vibrio cholerae.

22 Jan 2024

DNA Repair Breakthrough: Scientists Reveal RecA's Precise Helix Navigation

Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a dangling single-strand end into intact double strands, and repairing the break based on the undamaged sequence.

22 Jan 2024