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Researchers discover protein involved in protecting B cells

Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system's most important strategies involves B lymphocytes, also known as B cells, which produce antibodies that target and neutralize pathogens.

2 Jul 2020

Single-cell sequencing can reveal genetic diversity of cancer cells

In the past, the potential to sequence the genome of the tumor has redefined the treatment of cancer by detecting cancer drivers at the molecular level.

26 Jun 2020

Helping to unravel the genetic diversity of cancer tumors

The ability to sequence the genome of a tumor has revolutionized cancer treatment over the years by identifying drivers of cancer at the molecular level.

26 Jun 2020

Transcriptomic data can help track Neanderthal-derived RNA

Scientists are taking stem cell technology and using it to explore the developmental impacts of Neanderthal DNA.

19 Jun 2020

Loss of lipid-regulating protein drives prostate cancer metastasis

Johns Hopkins Kimmel Cancer Center researchers from the Department of Radiation Oncology and Molecular Radiation Sciences identified a lipid-regulating protein that conveys what the researchers describe as "superpowers" onto prostate cancer cells, causing them to aggressively spread.

17 Jun 2020

Fish Oil May Help With Depression

A study shows that patient-derived adult stem cells can be used to model major depressive disorder and test how a patient may respond to medication.

17 Jun 2020

Combination drugs for COVID-19 show promise in laboratory tests

Six months into the COVID-19 pandemic, more than 7.4 million people have been infected, and more than 410 000 have died. As yet, there is no treatment or vaccine for the disease.

16 Jun 2020

Study investigates how cancer adapts its metabolism to overcome treatment

Knowing what cancer will do next could lessen the likelihood of it becoming resistant to treatment. A new Canadian study investigates how cancer adapts its metabolism to potentially overcome therapies still in development.

From University of Toronto 9 Jun 2020

Chemicals Often Found In Consumer Products Could Lead To Obesity And Fatty Liver Diseases

Chemical compounds found in many consumer products could be major contributors to the onset of lipid-related diseases, such as obesity according to a study.

22 May 2020

mTOR gene in GvHD patients regulates cell growth and cell survival

Mutations that occur in white blood cells can play a major role in abnormal immune profile following hematopoietic stem cell transplantation.

11 May 2020

Study reveals the mechanism used by tuberculosis bacteria for their growth

The structure of a protein that plays a role in importing vitamin B12 into the cells of a tuberculosis (TB)-causing bacterium has been revealed by scientists from the Netherlands, Russia, the United States, and Sweden.

23 Apr 2020

Proving the existence of metabolons

For over four decades, researchers have proposed the presence of enzyme clusters, also called metabolons, which help facilitate several processes within cells.

17 Apr 2020

Study examines molecular causes of spondylocostal dysostosis

Researchers from EMBL Barcelona’s Ebisuya group collaborated with colleagues from RIKEN, Kyoto University, and Meijo Hospital in Nagoya, Japan, to investigate oscillating patterns of gene expression, coordinated across time and space within a tissue grown in vitro.

7 Apr 2020

Intact Protein Mass Spectrometry of Cell Culture Harvest Guides Cell Line Development for Trispecific Antibodies

A team in Massachusetts has established a method of profiling of mispairing in antibody assembly.

18 Feb 2020

A new study finds a potential immunotherapeutic pan-target on cancer cells

In a genome-wide CRISPR-Cas9 screen published in Nature Immunology in January 2020, a group of researchers described a potential universal target on cancer cells.

12 Feb 2020