Cell Nucleus News and Research

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Novel Role for Disordered Protein in Coordinating Key Stages of Gene Expression

Research reveals TAF2's disordered region links transcription and RNA editing, highlighting its role in gene expression regulation and nuclear organization.

15 May 2025

Research Unveils Mechanism Behind Evolution of Organelles from Bacteria

Organelles in cells were originally often independent cells, which were incorporated by host cells and lost their independence in the course of evolution.

20 Mar 2025

Extrachromosomal DNA Discovered as a Hidden Factor in Pancreatic Cancer Survival

Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%.

14 Mar 2025

High-Resolution Images Reveal How Cells Discard Faulty Spliceosomes

A sophisticated molecular machine, the spliceosome, ensures the accurate assembly of genetic information from the genome into mature mRNA after it has been transcribed into mRNA precursors.

10 Feb 2025

New Discovery Reveals How Tumor Stiffness Drives Cancer Progression

In 2022 alone, over 20 million people were diagnosed with cancer, and nearly 10 million died from the disease, according to the World Health Organization.

23 Dec 2024

New Mechanism for Precise Protein Production Unveiled

A new process that is essential to the synthesis of cellular proteins has been discovered by an international research team.

15 Nov 2024

Novel Mechanism for GRB2-SOS1-Mediated Liquid-Liquid Phase Separation

Researchers at Tokyo Metropolitan University have discovered new details about how the proteins GRB2 and SOS1 in cells transmit signals from membrane receptors to nuclei.

28 Oct 2024

Unraveling the Mechanics Behind Transcription-Dependent Motions of Single Genes

A group of researchers has found unexpected links between genome packing, gene activity, and genome-wide motions, exposing features of the genome's structure that have a direct impact on gene expression and regulation.

23 Oct 2024

Study Identifies Novel Chromatin Configuration in Turtle Genomes

Researchers from UAB and Iowa State University have produced the first-ever genome assemblies of two hidden-neck turtle species.

22 Oct 2024

New Discovery Reveals How MX Protein Traps HIV and Herpes Viruses

A group of researchers led by Xavier Saelens and Sven Eyckerman at the VIB-UGent Center for Medical Biotechnology discovered how a protein linked to the human immune system wards off HIV-1 and herpes simplex virus-1 by assembling structures in the cell that lure in these viruses and then trap them or even take them apart.

11 Oct 2024

New Insights into the Epigenetic Hallmarks of Cancer

Cancer mortality has just surpassed cardiovascular disease for the first time ever and one in two men, and one in three women, will be diagnosed with some form of the disease in the US, according to the NIH.

3 Oct 2024

Research Uncovers Dynamic Epigenetic Switch for Gene Expression Control

One of the most fascinating discoveries in biology is that cells have mechanisms for dynamically regulating genetic expression.

11 Sep 2024

CDCA7's Role in DNA Methylation Maintenance Revealed in Recent Study

DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and a major way that DNA is epigenetically marked. Epigenetic modifications can act as on-off switches to regulate gene expression and help generate diverse cell types without changing the underlying DNA sequence. It is how the body ensures that brain-related genes don't get turned on in heart cells, for example.

28 Aug 2024

Flavivirus Hijacks Importin-7 for Nuclear Transport and Replication

Viruses of the family Flaviviridae, including Japanese encephalitis virus (JEV), Dengue virus (DENV), Zika virus (ZIKV), West Nile virus (WNV), and Tick-borne encephalitis virus, are significant arthropod-borne pathogens.

15 Aug 2024

Scientists Discover Fossils of Ancient Chromosomes in the Remains of Woolly Mammoth

A team led by scientists from Baylor College of Medicine, University of Copenhagen, and Centre Nacional d'Anàlisi Genòmica and Centre for Genomic Regulation report discovering fossils of ancient chromosomes in the remains of a woolly mammoth that died 52,000 years ago.

12 Jul 2024