Chemotherapy, in its most general sense, is the treatment of disease by chemicals especially by killing micro-organisms or cancerous cells. In popular usage, it refers to antineoplastic drugs used to treat cancer or the combination of these drugs into a cytotoxic standardized treatment regimen.
Scientists have discovered a crucial biomolecule that improves the repair of a person’s gut lining by encouraging stem cells to regenerate impaired tissues.
Researchers at the University of Arkansas have developed a new nano drug candidate that kills triple negative breast cancer cells.
In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of cancerthe cells.
Researchers at UPMC Children's Hospital of Pittsburgh found that infusing umbilical cord blood -- a readily available source of stem cells -- safely and effectively treated 44 children born with various non-cancerous genetic disorders, including sickle cell, thalassemia, Hunter syndrome, Krabbe disease, metachromatic leukodystrophy (MLD) and an array of immune deficiencies.
Scientists at Hokkaido University and collaborators have identified how inflammatory changes in tumors caused by chemotherapy trigger blood vessel anomalies and thus drug-resistance, resulting in the poor prognosis of cancer patients.
Fresh insights into why some harmful substances are so efficient at causing cancer could aid the quest for better treatments.
CAR T cell therapy is a new and, in some cases, highly effective form of immunotherapy to treat certain types of cancer of the blood and lymph system.
By preventing sugar uptake, researchers succeeded in increasing the cancer cells' sensitivity to chemotherapeutic treatment.
A new precision medicine targeting cancer's ability to repair its DNA has shown promising results in the first clinical trial of the drug class.
A novel molecule LIH383 developed by scientists at the Luxembourg Institute of Health binds to and inhibits a formerly unknown opioid receptor in the brain.
Like any cells in the body, cancer cells need sugar - namely glucose - to fuel cell proliferation and growth. Cancer cells in particular metabolize glucose at a much higher rate than normal cells.
In the watery inside of a cell, complex processes take place in tiny functional compartments called organelles. Energy-producing mitochondria are organelles, as is the frilly golgi apparatus, which helps to transport cellular materials. Both of these compartments are bound by thin membranes.
As many cancer patients will confirm, the chemotherapy prescribed to kill the disease is often more debilitating than the cancer itself, with a range of horrendous side effects.
A study led by the Institut de Neurociències describes a new strategy to tackle cancer, based on inducing a potent stress in tumor causing cell destruction by autophagy.
The p53 gene is crucial in cell biology and thus cell replacement therapy. The function of this gene is to control the cell cycle and stop tumor formation.
Removing a malignant brain tumor is a balancing act between protecting the healthy tissue and, at the same time, excising as much tumor tissue as possible.
For many years, researchers have analyzed the use of liposomes, which are hollow spheres composed of lipid bilayers, to transmit chemotherapy drugs to tumor cells.
As we know, a malignant tumor is a complex system of mutated cells which constantly interacts with and involves healthy cells in the body.
Scientists at the Stem Cell Research program at Boston Children's Hospital and Dana-Farber Cancer Institute/Harvard Medical School have devised a mouse model that lets researchers track every cell in the body, from the embryonic stage until adulthood.
There are immune cells in our bodies that directly destroy infected or cancer cells - they are called natural killer cells. Recently, a POSTECH research team has developed an integrative cancer therapy using adoptive natural killer cell therapy and chemotherapy.