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Study shows why obese mothers tend to have children susceptible to metabolic diseases

A Brazilian study published in the journal Molecular Human Reproduction helps understand why obese mothers tend to have children with a propensity to develop the metabolic disease during their lifetime, as suggested by previous research.

27 Jan 2021

New CAR T therapy could be more effective and less toxic against neuroblastoma

CAR T therapy has transformed the treatment for leukemia. Regrettably, the therapy is not effective enough to treat solid tumors, like neuroblastoma.

22 Jan 2021

Study: Vegan diet has broad effect on children's metabolism

The study concludes that vegan diet has a broad effect on children's metabolism. Serum biomarker levels for vitamins A and D, cholesterol forms and essential amino acids were significantly lower in children on vegan diet compared to age-adjusted omnivores.

22 Jan 2021

Immunity of COVID-19 patients may rely on antibodies from previous coronavirus infections

The results of a study led by Northern Arizona University and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest the immune systems of people infected with COVID-19 may rely on antibodies created during infections from earlier coronaviruses to help fight the disease.

22 Jan 2021

Immature dendritic cells in young children can induce robust immune responses

A new study performed by scientists from Ludwig-Maximilians-Universitaet Muenchen (LMU) has demonstrated that putatively immature dendritic cells in young children can trigger powerful immune responses. The findings may result in better vaccination protocols.

21 Jan 2021

Study reveals genetic variants that increase the risk of nocturnal enuresis

In a large-scale study of Danish children and young people, researchers from Aarhus University have for the first time found genetic variants that increase the risk of nocturnal enuresis - commonly known as bedwetting or nighttime incontinence. The findings provide completely new insights into the processes in the body causing this widespread phenomenon.

20 Jan 2021

Fecal microbiome differs in healthy and food-allergic twins

A new study out of the University of Chicago and Stanford University on pairs of twins with and without food allergies has identified potential microbial players in this condition. The results were published on Jan. 19 in the Journal of Clinical Investigation.

20 Jan 2021

Exaggerated activation of food quality control system may explain the rising food allergies

For more than three decades, food allergies have been rising drastically across the developed world.

15 Jan 2021

Scientists identify the sensor in human lungs that detects SARS-CoV-2

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified the sensor in human lungs that detects SARS-CoV-2 and signals that it's time to mount an antiviral response.

13 Jan 2021

Automated electron microscopy helps visualize neural function and behavior

Researchers are still clueless about how the neural networks are linked together to make functional circuits.

From Harvard Medical School 12 Jan 2021

Scientists use stem cells to reverse memory and learning deficits in mice with craniosynostosis

In an effort to regenerate portions of the skull, researchers have successfully used stem cells, corrected the shape of the skull, and thus reversed learning and memory deficits in young mice afflicted with craniosynostosis.

8 Jan 2021

Study explores why Shiga toxin-producing E. coli infections are so dangerous

E. coli food poisoning is one of the worst food poisonings, causing bloody diarrhea and kidney damage. But all the carnage might be just an unintended side effect, researchers from UConn Health report in the 27 November issue of Science Immunology. Their findings might lead to more effective treatments for this potentially deadly disease.

7 Jan 2021

Researchers create molecular ON-OFF switches to regulate CAR T cell activity

CAR T cells are a breakthrough class of effective but often toxic cancer therapies. To prevent overactivation, switchable CAR T cells were engineered that can be turned on and off with an approved, widely used cancer drug.

7 Jan 2021

DNA-editing technique used to extend lifespan of mice with progeria

Researchers have successfully used a DNA-editing technique to extend the lifespan of mice with the genetic variation associated with progeria, a rare genetic disease that causes extreme premature aging in children and can significantly shorten their life expectancy.

From National Human Genome Research Institute (NHGRI) 7 Jan 2021

Longitudinal study identifies many genetic markers linked to bone mineral accrual

A multidisciplinary team of researchers led by Children's Hospital of Philadelphia has discovered several genetic markers associated with bone mineral accrual, which could ultimately help identify causes of eventual osteoporosis earlier in life through genetic testing.

7 Jan 2021

Gut cells raise alarm during parasite invasion

To effectively combat an infection, the body first has to sense it's been invaded, then the affected tissue must send out signals to corral resources to fight the intruder.

29 Dec 2020

Researchers reconstruct the chewing motion of an early mammal

Paleontologists at the University of Bonn (Germany) have succeeded in reconstructing the chewing motion of an early mammal that lived almost 150 million years ago.

24 Dec 2020

Scientists discover molecular defects associated with rare genetic disorder in children

Damien D'Amours and his team at the Ottawa Institute of Systems Biology needed three years to discover the molecular defects associated with the LIC Syndrome, a serious genetic disorder that affects young children and result in acute respiratory distress, immune deficiency and abnormal chromosomes.

23 Dec 2020

Anti-diarrhea drug could be used to induce cell death in glioblastoma cell lines

The research group led by Dr Sjoerd van Wijk from the Institute of Experimental Cancer Research in Paediatrics at Goethe University already two years ago found evidence indicating that the anti-diarrhea drug loperamide could be used to induce cell death in glioblastoma cell lines.

23 Dec 2020

TGen identifies genetic target that could help explain the variation in COVID-19 effects

The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become.

17 Dec 2020

Children News and Research

Study shows why obese mothers tend to have children susceptible to metabolic diseases

New CAR T therapy could be more effective and less toxic against neuroblastoma

Study: Vegan diet has broad effect on children's metabolism

Immunity of COVID-19 patients may rely on antibodies from previous coronavirus infections

Immature dendritic cells in young children can induce robust immune responses

Study reveals genetic variants that increase the risk of nocturnal enuresis

Fecal microbiome differs in healthy and food-allergic twins

Exaggerated activation of food quality control system may explain the rising food allergies

Scientists identify the sensor in human lungs that detects SARS-CoV-2

Automated electron microscopy helps visualize neural function and behavior

Scientists use stem cells to reverse memory and learning deficits in mice with craniosynostosis

Study explores why Shiga toxin-producing E. coli infections are so dangerous

Researchers create molecular ON-OFF switches to regulate CAR T cell activity

DNA-editing technique used to extend lifespan of mice with progeria

Longitudinal study identifies many genetic markers linked to bone mineral accrual

Gut cells raise alarm during parasite invasion

Researchers reconstruct the chewing motion of an early mammal

Scientists discover molecular defects associated with rare genetic disorder in children

Anti-diarrhea drug could be used to induce cell death in glioblastoma cell lines

TGen identifies genetic target that could help explain the variation in COVID-19 effects

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