Chromatin News and Research

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Statistical methodology uncovers changes in genomic data

A novel statistical technique makes it easier to find biologically significant changes in genomic data that span multiple conditions, like cell types or tissues.

From Penn State University 15 Nov 2022

Researchers uncover a mechanism of flowering plant sperm compaction

Sperm cells have compact bundles of DNA, yet exactly how and why sperm cell nuclei are condensed in flowering plants has been a mystery, until now.

4 Nov 2022

Genome of the earliest common ancestor of all mammals identified

From a platypus to a blue whale, all living mammals today are derived from a single ancestor that existed around 180 million years ago. Although nothing much is known about this species, an international team of experts has now computationally rebuilt how its DNA is organized.

From The University of California, Davis 28 Sep 2022

Understanding the structure of the nucleus inside a cell using mathematics

Recent work shows a novel mathematical approach to start comprehending how a cell’s nucleus is structured.

21 Sep 2022

Unique combination of transcription factors trigger cell regeneration in zebrafish

Scientists at the National Institutes of Health have identified a particular protein network required for cell regeneration to restore hearing in zebrafish.

From National Human Genome Research Institute (NHGRI) 15 Sep 2022

Chromatin displays different dynamics in cells during organ-formation

Recent research from the School of Medicine has illuminated the development of the liver, lungs, and digestive system. This result may have significant ramifications for the comprehension of cancer.

30 Aug 2022

Diseased connective tissue cells alter the physical structure of their genomes

Researchers at Penn Medicine have found that when cells are impacted by the disease, the physical structure of their genome changes.

25 Aug 2022

Study discovers a molecular mechanism that confers special physical properties to chromosomes in dividing human cells

The Gerlich Group at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) has identified a molecular process that gives chromosomes in dividing human cells unique physical characteristics that permit faithful transmission to the progeny.

8 Aug 2022

SLFN11’s surveillance part in protein homeostasis

On July 25th, 2022, a new study perspective called “SLFN11’s surveillance role in protein homeostasis” was published in Volume 9 of Oncoscience.

8 Aug 2022

Experts develop new single-cell “chromatin atlas” of the human genome

Researchers from the University of Virginia School of Medicine have developed a crucial new tool that provides a better understanding of how genes in particular cells affect the risk of developing heart disease, the world’s leading cause of death.

25 Jul 2022

Researchers get deep insights into the functionality of human genome

Scientists from Weill Cornell Medicine and the New York Genome Center, in partnership with Oxford Nanopore Technologies, have introduced a new method for assessing the three-dimensional structure of the human genome, as well as how the genome folds, on a large scale.

27 Jun 2022

Study reveals how amphioxus model analyze the genesis and vertebrates evolution

The two rounds of whole-genome duplication that occurred throughout the evolution of vertebrates were followed by functional divergence in terms of regulatory circuits as well as gene expression patterns.

27 Jun 2022

Scientists discover proteins that may improve CAR-T cell therapy for solid tumor model

The potential of CAR T-cell therapy for the treatment of solid tumors was unlocked in a preclinical trial by researchers at St. Jude Children’s Research Hospital who discovered a molecular mechanism. The findings were released in the journal Nature.

27 Jun 2022

Origin of chromatin in ancient microbes happened 1–2 billion years ago, study reveals

Nature’s storage solution originally emerged in ancient microbes living on Earth around one and two billion years ago, according to researchers at the Center for Genomic Regulation (CRG).

10 Jun 2022

Researchers conduct a comprehensive survey of the aging epigenome across the chromatin hierarchy

Highly structured chromatin encodes the program of life with only one set of genes in the core of every cell. Since various genes are stimulated at different periods of life while staying silent elsewhere, this is feasible. Some genes from a former life stage are hidden deep within the nuclear perimeter, while others manage to break out.

1 Jun 2022

Study highlights the interaction between single-stranded DNA and the linker histone H1

Human DNA is neatly locked in place around a central disc in the tight quarters of the cell nucleus by H1 linker histone that helps shepherd DNA into the tidy chromatin fibers that make up chromosomes. The linker histone, on the other hand, is much more than a protein clip.

31 May 2022

Specialist assay kits and microplates for cancer research

Porvair Sciences will exhibit its latest assay kits and microplates for cancer and life science research at the American Association for Cancer Research (AACR) meeting in New Orleans, USA from the 8th – 13th April 2022.

From Porvair Sciences Limited 7 Apr 2022

Yale and uOttawa researchers partner to solve a puzzle rooted in the deepest past of evolution

For decades, scientists have been trying to unravel an enduring mystery of structural biology: Why do two otherwise identical protein forms found in everything from plants, amphibians and human beings hang onto a slight variation across the mighty span of evolution?

21 Mar 2022

Salk researchers present novel technology to assist in examining single brain cells

Researchers at the Salk Institute have created a novel genomic technology that enables them to study DNA, RNA, and chromatin from a single cell at the same time.

11 Mar 2022

Reversing the destructive aging process in egg cells to increase fertility in older women

Throughout much of the world, increasing numbers of women are delaying having their first child until they are in their late thirties, and even into their forties.

9 Mar 2022

Chromatin News and Research

Statistical methodology uncovers changes in genomic data

Researchers uncover a mechanism of flowering plant sperm compaction

Genome of the earliest common ancestor of all mammals identified

Understanding the structure of the nucleus inside a cell using mathematics

Unique combination of transcription factors trigger cell regeneration in zebrafish

Chromatin displays different dynamics in cells during organ-formation

Diseased connective tissue cells alter the physical structure of their genomes

Study discovers a molecular mechanism that confers special physical properties to chromosomes in dividing human cells

SLFN11’s surveillance part in protein homeostasis

Experts develop new single-cell “chromatin atlas” of the human genome

Researchers get deep insights into the functionality of human genome

Study reveals how amphioxus model analyze the genesis and vertebrates evolution

Scientists discover proteins that may improve CAR-T cell therapy for solid tumor model

Origin of chromatin in ancient microbes happened 1–2 billion years ago, study reveals

Researchers conduct a comprehensive survey of the aging epigenome across the chromatin hierarchy

Study highlights the interaction between single-stranded DNA and the linker histone H1

Specialist assay kits and microplates for cancer research

Yale and uOttawa researchers partner to solve a puzzle rooted in the deepest past of evolution

Salk researchers present novel technology to assist in examining single brain cells

Reversing the destructive aging process in egg cells to increase fertility in older women

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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