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Immune cell migration contributes to inefficient antitumor immunity, study finds

Mutations in the APC gene cause the production of intestinal polyps in persons suffering from familial adenomatous polyposis, a genetic disease that predisposes them to colon cancer.

From Institut Pasteur 15 Apr 2022

Critical signaling pathways in immune cells could reduce Alzheimer’s progression

According to Weill Cornell Medicine researchers, inhibiting a critical signaling route in brain-resident immune cells may reduce brain inflammation and hence halt the progression of the disease in Alzheimer’s and other neurodegenerative disorders.

15 Apr 2022

A new Yale study identifies a deeper understanding of cancer-relevant genes

According to a Yale Cancer Center study, there is cancer-relevant value in a substantially greater portion of human genes than existing cancer research models suggest, based on a study of over 12,000 human genes.

15 Apr 2022

Study reveals key characteristics of immune cells in ovarian cancer

Ovarian cancer is a difficult to diagnose malignancy that is often caught at a more advanced stage. Treatments for this cancer have changed little over the past few decades, with surgery and chemotherapy being the most common therapeutic approaches.

15 Apr 2022

Cell-derived therapy may help treat ventricular arrhythmia

Vesicles secreted from human heart cells may repair damaged tissue and prevent lethal heart rhythm disorders, according to a new study from investigators in the Smidt Heart Institute at Cedars-Sinai.

13 Apr 2022

VectorBuilder to expand with $500 million ‘Gene Delivery Research and Manufacturing Campus

VectorBuilder Inc. has announced the construction of a new R&D and manufacturing center in Guangzhou, China.

From VectorBuilder 12 Apr 2022

Gut viruses contribute to human health, but provoke inflammation when perturbed

Research in recent years has demonstrated the diverse roles that gut bacteria can play in health and disease, but what about contributions from viruses, which, like bacteria, perpetually reside within the human intestine?

11 Apr 2022

Researchers create RNA molecules to address human pancreatic beta cells

Researchers at the University of Miami Miller School of Medicine have created RNA molecules that bind to human pancreatic beta cells, which generate insulin and are destroyed in type 1 and type 2 diabetes patients.

11 Apr 2022

Study shows how biodegradable gel helps immune system to keep cancer away

After tumors are surgically removed, a novel biodegradable gel increases the immune system’s capacity to keep cancer away.

11 Apr 2022

Research sheds light on non-invasive conjunctival goblet cell testing in patients

Conjunctival Goblet Cells (CGCs) are specialized epithelial cells that secrete mucins to generate the tear film’s mucus layer.

11 Apr 2022

Researchers identify specific genes that cause schizophrenia

A substantial number of individual genes that potentially play essential roles in schizophrenia have been uncovered in the largest-ever genomic analysis of the psychiatric condition.

11 Apr 2022

Intracellular microbiota promote cell survival during tumor progression

Bacteria promote cancer metastasis by bolstering the strength of host cells against mechanical stress in the bloodstream, promoting cell survival during tumor progression, researchers report April 7th in the journal Cell.

8 Apr 2022

Understanding the role of ORF8 viral gene in COVID-19 infection and outcomes

A research team led by Jae Jung, PhD, Director of Cleveland Clinic's Global Center for Pathogen & Human Health Research, has uncovered the critical role a viral gene, ORF8, plays in infection and disease outcomes of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19.

8 Apr 2022

A mitochondrial uncoupler prevents sarcopenic obesity in elderly mice

A recently discovered chemical compound helped elderly mice with obesity lose fat and weight, add muscle and strength, reduce age-related inflammation and increase physical activity, a new study shows.

7 Apr 2022

Specialist assay kits and microplates for cancer research

Porvair Sciences will exhibit its latest assay kits and microplates for cancer and life science research at the American Association for Cancer Research (AACR) meeting in New Orleans, USA from the 8th – 13th April 2022.

From Porvair Sciences Limited 7 Apr 2022

Study sheds light on genetic causes of Alzheimer’s disease and other dementias

If we want to enhance our knowledge and treatment of Alzheimer’s disease, we need to identify genetic risk factors.

7 Apr 2022

Breakthrough discovery provides a desirable drug target to tackle metabolic diseases

In a breakthrough discovery, scientists from The University of Texas Health Science Center at San Antonio today reported that inhibiting a liver enzyme in obese mice decreased the rodents' appetite, increased energy expenditure in adipose (fat) tissues and resulted in weight loss.

6 Apr 2022

Gut microbiota may play a role in resistance to blood pressure medicines

Almost half of the U.S. adult population has high blood pressure - or hypertension - and about 20% of these patients have treatment-resistant hypertension.

6 Apr 2022

A critical subset of supporting cells may lie at the origins of scleroderma

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital.

5 Apr 2022