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Novel precision medicine targets cancer's DNA defenses

A new precision medicine targeting cancer's ability to repair its DNA has shown promising results in the first clinical trial of the drug class.

23 Jun 2020

Developments in Engineered T Cells for Type 1 Diabetes

AZoLifeSciences speaks to Professor David J. Rawlings from the Seattle children's hospital about recent developments in engineered T cells for type 1 diabetes.

23 Jun 2020

Study shows MMR vaccine may protect against COVID-19 symptoms

According to a group of experts, the administration of the MMR vaccine could act as a preventive measure to reduce inflammation linked to COVID-19 infection.

22 Jun 2020

Researchers identify antibody cocktail with potential to neutralize SARS-CoV-2 virus

Researchers at the University of Maryland School of Medicine evaluated several human antibodies to determine the most potent combination to be mixed in a cocktail and used as a promising anti-viral therapy against the virus that causes COVID-19.

17 Jun 2020

A protein that helps to fight viruses can also inhibit lung tissue repair

Researchers at the Francis Crick Institute have found that a protein which is initially helpful in the body’s immune response to a virus, can later interfere with the repair of lung tissue.

12 Jun 2020

Study identifies new pathway to attack tumor cells

A study led by the Institut de Neurociències describes a new strategy to tackle cancer, based on inducing a potent stress in tumor causing cell destruction by autophagy.

10 Jun 2020

Inhibiting host cell proteases can help prevent COVID-19 infection

How can we prevent the novel coronavirus from invading a host cell in an attempt to prevent infection?

2 Jun 2020

A 'Switch' That Turns Autoimmunity Drugs Into Powerful Anti-Cancer Treatments

Scientists have discovered a way to transform antibody drugs into antibodies with powerful anti-cancer activity through a simple molecular "switch".

22 May 2020

Scientists study how brain cancer cells acquire radiation resistance

In a vertical climb to avoid collision with a towering mountain, a plane ejects cargo to gain altitude. Investigators at the University of Minnesota showed that cancer cells perform similar feats in escaping the killing effects of radiation.

18 May 2020

Genome-wide pattern found in glioblastoma tumors predicts patient survival

For the past 70 years, the best indicator of life expectancy for a patient with glioblastoma (GBM) -- the most common and the most aggressive brain cancer -- has simply been age at diagnosis.

15 May 2020

Anti-cancer medicine could improve current therapy for ER+ breast cancer

The anti-cancer medicine venetoclax could improve the current therapy for estrogen receptor-positive (ER+) breast cancer - the most common form of breast cancer in Australia - according to preclinical studies led by Walter and Eliza Hall Institute researchers.

7 May 2020

Blood Filter May Calm The Cytokine Storm Of COVID-19

COVID-19 is causing organ destruction and death, and physicians are replacing the filter in a kidney dialysis machine to trap these tiny proteins.

5 May 2020

Variation In How Side Effects Are Reported Clouds Drug Safety

A goal of early-phase clinical trials is to discover a drug's possible side effects. But there is significant variation in how drug side effects are reported.

29 Apr 2020

Study finds utrophin-based therapy could be used to treat Duchenne muscular dystrophy

If an actor is not in a position to perform in the theatre, an understudy—preferably one with some practice in the role—can take that role on stage.

27 Apr 2020

Combination therapy encourages innate immune cells to eat GBM tumors

A combination of immunotherapy agents that encourages some immune cells to eat cancer cells and alert others to attack tumors put mice with a deadly type of brain cancer called glioblastoma into long-term remission, a new study led by UT Southwestern scientists suggests.

24 Apr 2020

Scientists find gene signature linked to worst prognosis in rare uterine cancer

Women who don't survive a rare and aggressive uterine cancer called uterine serous carcinoma, have high expression of a group of 73 genes, a score scientists say can help identify these women and improve their outcome.

22 Apr 2020

Gene Variant Staves Off Alzheimer's In Some People

People with a gene that puts them at risk for Alzheimer's disease are protected from its debilitating effects if they also carry a variant of a different gene.

17 Apr 2020

Discovery Of New Biomarker In Blood Could Lead To Early Test For Alzheimer's Disease

Researchers discovered that high blood levels of RNA produced by the PHGDH gene could serve as a biomarker for early detection of Alzheimer's disease.

2 Apr 2020

Researchers Discover Potential Boost To Immunotherapy

Researchers have discovered a pathway that regulates special immune system cells in lung cancer tumors, suppressing them and allowing tumors to grow.

2 Apr 2020

Stem cell strategy can help improve the effectiveness of cardiac repair

Human stem cells have been typically perceived as one of the potential cell sources for cardiac regeneration treatment. However, the substandard performance following transplantation into the failing hearts has limited their applications in clinical use.

30 Mar 2020