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Using Mass-Spectrometry-Based Cancer Proteomics Datasets to Discover Potential Therapeutic Targets

A new research perspective was published in Oncotarget's Volume 14 on May 4, 2023, entitled, "Using cancer proteomics data to identify gene candidates for therapeutic targeting."

11 May 2023

Cancer Stem Cell Test can Accurately Decide More Effective Treatments for Glioblastoma Patients

New multi-institutional phase 3 clinical trial data published May 2 in Cell Reports Medicine found that a cancer stem cell test can accurately decide more effective treatments and lead to increased survival for patients with glioblastoma, a deadly brain tumor.

8 May 2023

Engineered Sustainable, Patient-Specific NPCs Could Help Treat Neurodegenerative Diseases

Progressive loss of neurons is the underlying cause for a diverse spectrum of severe diseases called neurodegenerative diseases, which include Parkinson's disease, amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa.

21 Apr 2023

Study Presents Crucial Themes in the Biology of Pancreatic Cancer

Scientists from the University of California, Irvine, the University of Michigan and the University of Texas MD Anderson Cancer Center have made a significant contribution to the field of pancreatic cancer research.

17 Apr 2023

Specialized Diet Stimulates a Unique Form of Programmed Cell Death

Glioblastoma is the most prevalent kind of adult brain tumor.

10 Apr 2023

Newly developed toolkit uses small molecules to control the activity of synthetic RNA

The Okinawa Institute of Science and Technology, in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses small molecules to control the activity of a piece of synthetic RNA, and ultimately regulate gene expression.

31 Mar 2023

Maternal vaginal microbiome does not substantially influence the infant stool microbiome

It has been a longstanding assumption that birth mode and associated exposure of newborns to their mothers' vaginal microbiome during delivery greatly affects the development of babies' gut microbiome.

31 Mar 2023

Single monoclonal antibody infusion can strengthen the body's fight against yellow fever

New research from Oregon Health & Science University and collaborators indicates lab-made antibodies may be able to cure people infected with yellow fever, a virus for which there is no treatment.

30 Mar 2023

Using better probiotics to maintain a healthy gut microbiome

Bacteria have thousands of genes and functions that we, the human host, do not have. For instance, bacteria can help us digest fiber, provide support to our immune systems, and absorb important nutrients. But reaping the benefits of "good bacteria" is easier said than done.

29 Mar 2023

Common Epstein-Barr virus may be a trigger for multiple sclerosis

In 1868, French physician Jean-Martin Charcot, known as the founder of modern neurology, defined a disease entity in which multiple plaques formed in the brain and spinal cord, with varying physical symptoms, called Sclérose en plaques, or in English as multiple sclerosis (MS).

24 Mar 2023

Using AI to screen for genetic mutations in cancerous brain tumors in under 90 seconds

Using artificial intelligence, researchers have discovered how to screen for genetic mutations in cancerous brain tumors in under 90 seconds -; and possibly streamline the diagnosis and treatment of gliomas, a study suggests.

24 Mar 2023

Using viruses to fight antibiotic-resistant "superbugs"

The Centers for Disease Control and Prevention warns that the increase in cases of the drug-resistant bacterial infection Shigella could be a predictor of what's to come for other bacteria.

22 Mar 2023

Keck Medicine of USC launches clinical trial investigating innovative procedure to control Type 2 diabetes

More than 37 million Americans have diabetes, and approximately 90-95% have Type 2 diabetes.

21 Mar 2023

Keeping lymph nodes in the body can boost the efficacy of cancer immunotherapy

Cancer treatment routinely involves taking out lymph nodes near the tumor in case they contain metastatic cancer cells.

21 Mar 2023

DNA drugs help restore the normal processing of protein-encoding RNA

A protein named TDP-43 has been lost from its normal location in the nucleus of the cell in virtually all persons having amyotrophic lateral sclerosis (ALS) and in up to half of all cases of frontotemporal dementia and Alzheimer’s disease (AD).

From UC San Diego 20 Mar 2023

Perspectives on nucleolar DNA damage response in the fight against cancer

Cancer, which affects so many people each year, relies on proteins to proliferate throughout the body. Scientists are damaging the disease’s protein factories as part of a new tactic to combat the widespread disease.

20 Mar 2023

Delaying paralysis in ALS by using designer DNA drug

In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer's disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus of the cell.

20 Mar 2023

Experts receive funding to analyze individualized hemodialysis as a dynamic treatment

The Patient-Centered Outcomes Research Institute (PCORI) recently awarded researchers at Wake Forest University School of Medicine $10.2 million to study the effectiveness of an individualized model of hemodialysis, a procedure in which the blood is cleaned by a dialysis machine. The project is a collaboration between the School of Medicine, the Renal Research Institute and other health care systems across the country.

10 Mar 2023

Potential therapeutic can synergize with existing drugs to effectively destroy leukemia cells

A team of researchers has discovered a potential therapeutic that can synergize with existing drugs to more effectively kill certain leukemia cells.

9 Mar 2023

Revolutionary drug blocks a gene associated with driving the spread of bone cancer

Researchers at the University of East Anglia have developed a new drug that works against all of the main types of primary bone cancer.

8 Mar 2023