Colon Cancer News and Research

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Every year, about one million new cases of colon cancer are diagnosed worldwide. About 150,000 new cases are detected each year in the United States. Over a lifetime, about 1 in 19 people develop colon cancer and nearly 50,000 people are expected to die from it in the U.S. this year. According to the American Cancer Society, colon cancer is the third leading cause of cancer-related death in the U.S., accounting for about 10 percent of all cancer deaths.

NIH funds research on mRNA vaccines to stop cancer development

The National Cancer Institute at the National Institutes of Health has awarded a multidisciplinary team of Weill Cornell Medicine researchers a five-year $5.7 million grant to support a center dedicated to creating messenger RNA (mRNA) vaccines to prevent the development of cancer in at-risk groups.

15 Nov 2022

Novel high-resolution taxonomy facilitates effective management of CRC patients

Recent research discovered that bowel tumors can be classified into six clinically relevant subcategories based on patterns of gene interactions seen within tumor cells. The study was published in eLife.

10 Nov 2022

New gene linked to the growth of colon cancer discovered

Researchers at Mount Sinai’s Tisch Cancer Institute have discovered a new gene that is crucial to the development of colon cancer and established that inflammation in the region surrounding the tumor can contribute to the development of tumor cells.

20 Oct 2022

Novel nanoparticle therapeutic shows potential for treating human cancers

Researchers from Wake Forest University School of Medicine have discovered a possible new approach to treating solid tumors through the creation of a novel nanoparticle. Solid tumors are found in cancers such as breast, head and neck, and colon cancer.

15 Jun 2022

Study shows new potential target for CAR T cells to inhibit solid tumors

CAR T therapy, or chimeric antigen receptor T-cell therapy, has revolutionized the treatment of some blood cancers, allowing patients with relapsed or refractory disease to live longer and better lives.

10 May 2022

Study shows how innate lymphoid cells may help to treat inflammatory bowel disease

A team of researchers at Sweden’s Karolinska Institutet studied how specific immune cells known as innate lymphoid cells (ILCs), which play a role in inflammatory bowel disease (IBD), evolve into mature cells.

18 Apr 2022

Immune cell migration contributes to inefficient antitumor immunity, study finds

Mutations in the APC gene cause the production of intestinal polyps in persons suffering from familial adenomatous polyposis, a genetic disease that predisposes them to colon cancer.

From Institut Pasteur 15 Apr 2022

New approach to assess motility and invasive capacity of cancer cells in a tissue section

There are many proteins involved in the spread of cancer. However, some of them are notably difficult to observe in patient tissue samples.

28 Mar 2022

New discovery likely to result in cancer vaccine development

According to research published in eLife, researchers have developed a pipeline for detecting, prioritizing, and testing potential tumor antigens for the rapid development of cancer vaccines.

23 Mar 2022

Researchers discover new fluorescent DNA label, likely to help detect cancer risk

Scientists develop a new fluorescent label that provides a sharper image of how DNA architecture is disturbed in cancer cells.

From University of Pittsburgh 7 Mar 2022

Researchers discover dysregulation of transfer RNA expression in cancer

A recently published paper in the journal Molecular Cancer by the group of Dr. Manel Esteller, Director of the Josep Carreras Leukaemia Research Institute, ICREA Research Professor and Genetics Chairman at the University of Barcelona, shows that transfer RNAs for certain amino acids are altered at the epigenetic level in some types of cancer, expressing it in an exaggerated manner in some cases and being deficient in others.

17 Feb 2022

Study: Global human microbiome research is heavily biased in favor of wealthy countries

New studies emerge daily on the effect of the human microbiome on human health: colon cancer, ulcers, and cognitive conditions such as Alzheimer's disease have been associated with the communities of microbes that live in our bodies.

16 Feb 2022

Synthetic food additive causes detrimental effects on the gut microbiota

New clinical research indicates that a widely used food additive, carboxymethylcellulose, alters the intestinal environment of healthy persons, perturbing levels of beneficial bacteria and nutrients.

1 Dec 2021

Treatment with common allergy medication linked to improved immunotherapy response

New research from The University of Texas MD Anderson Cancer Center found that treatment with antihistamines, a commonly used allergy medication, was associated with improved responses to immune checkpoint inhibitors.

29 Nov 2021

New molecule can effectively deplete cancer-protecting cells inside tumors

A new study has discovered a two-arm molecule that can effectively deplete cancer-protecting cells within tumors.

16 Aug 2021

Study analyzes the role of eIF4A3 protein in cancer cell growth

Cell growth requires new proteins and the same applies to cancer cells. Scientists analyzed the protein eIF4A3 and its role in the growth of cancer cells.

10 Aug 2021

Study explores the effectiveness of a natural protein against colon cancer cells

Scientists and faculty of Vanderbilt University are in search of the “Achilles’ heel” of cancer cells that survive initial chemotherapy.

From Vanderbilt University 5 Aug 2021

New multimodal diagnostic can detect cancer cells and pinpoint tumor location

Most of the tests that doctors use to diagnose cancer -- such as mammography, colonoscopy, and CT scans -- are based on imaging. More recently, researchers have also developed molecular diagnostics that can detect specific cancer-associated molecules that circulate in bodily fluids like blood or urine.

19 Jul 2021

Updated Families SHARE workbook helps people use family history to assess disease risk

The Families SHARE workbook was developed by researchers at the NHGRI, which is part of the National Institutes of Health (NIH).

12 Jul 2021

ASU study reveals how diets high in saturated fats cause colon cancer

For decades, physicians and dieticians have urged people to limit their intake of high fat foods, citing links to poor health outcomes and some of the leading causes of death in the U.S., such as diabetes, heart disease and cancer.

10 Jun 2021