Coronary Artery Disease News and Research

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Coronary artery disease is the most common type of heart disease and the leading cause of death worldwide. It occurs when the arteries that supply blood to the heart become narrowed or blocked by a buildup of "plaque" - cholesterol or other fatty deposits that build on the inner wall of the artery. Over time, this plaque build up results in a reduction of blood flow to the heart, which can cause chest pain. If the artery becomes completely blocked, usually by a blood clot, oxygen is prevented from reaching the heart which can result in a heart attack and/or damage to the heart tissue.

Study Reveals Genetics Behind Dilated Cardiomyopathy

A potentially life-changing heart condition, dilated cardiomyopathy, can be caused by the cumulative influence of hundreds or thousands of genes and not just by a single "aberrant" genetic variant, as was previously thought, finds a new study led by researchers at UCL (University College London), Imperial College London and the MRC Laboratory of Medical Sciences.

23 Nov 2024

Study Reveals Key Role of Viscoelasticity in Cellular Response to Mechanical Signals

A study by CNIC, published in Science Advances, offers a new approach to understanding how cells respond to mechanical signals from their environment, redefining the comprehension of the relationship between cells and their physical surroundings.

18 Nov 2024

AI Uncovers Rare Mutations with Major Impact on Heart Health

Researchers at the Icahn School of Medicine at Mount Sinai have discovered unusual coding variants in 17 genes that provide insight into the molecular causes of coronary artery disease (CAD), the world's leading cause of morbidity and mortality.

12 Jun 2024

Sphingolipid Mystery Solved: S1P May Protect Against Coronary Artery Disease

Weill Cornell Medicine investigators have uncovered a way to unleash in blood vessels the protective effects of a type of fat-related molecule known as a sphingolipid, suggesting a promising new strategy for the treatment of coronary artery disease.

25 Apr 2024

Genetic Clusters Linked to Type 2 Diabetes and Complications

The relationship between genetic variations and disease in order to create novel medications and therapies.

20 Feb 2024

Study Uncovers Novel Genes Linked to Coronary Artery Calcification

An international team of scientists has identified nearly a dozen genes that contribute to calcium buildup in our coronary arteries that can lead to life-threatening coronary artery disease, a condition responsible for up to one in four deaths in the United States.

12 Oct 2023

SARS-CoV-2 Infection is Significantly Linked With the Development of High Blood Pressure

An analysis of electronic medical records for more than 45,000 people found that COVID-19 infection was significantly associated with the development of high blood pressure, according to new research published today in Hypertension, an American Heart Association journal.

22 Aug 2023

New Genes Associated With SCAD Identified

The National Institute for Health and Care Research (NIHR) Leicester Biomedical Research Centre (BRC) and Universite Paris Cite have identified new genes linked with an increased incidence of a type of heart attack that primarily affects young to middle-aged women, with support from global partners in Canada, the United States, and Australia.

30 May 2023

Scientists Discover Gene That Plays a Key Role in Determining the Risk for Vascular Diseases

University of School of Medicine researchers have identified a gene that plays a crucial role in determining our risk for heart attacks, deadly aneurysms, coronary artery disease and other dangerous vascular conditions.

19 Apr 2023

High blood caffeine levels lower body fat and the long-term risks of type 2 diabetes, study finds

A high blood caffeine level might curb the amount of body fat a person carries and their risk of type 2 diabetes, suggests research published in the open access journal BMJ Medicine.

16 Mar 2023

Substituting meat for mycoprotein reduces intestinal genotoxins, increases healthy gut bacteria

Researchers from Northumbria University have found that swapping red and processed meat for Quorn's mycoprotein, a fungi-based meat alternative, leads to a significant reduction in intestinal genotoxins - which can cause bowel cancer - and increases healthy gut bacteria.

17 Feb 2023

New computational approach enhances the performance of bioinformatics tools

UVA Health researchers have created an innovative tool to assist scientists in distinguishing signals from noise as they investigate the genetic underpinnings of cancer and other disorders.

24 Nov 2022

Experts develop new single-cell “chromatin atlas” of the human genome

Researchers from the University of Virginia School of Medicine have developed a crucial new tool that provides a better understanding of how genes in particular cells affect the risk of developing heart disease, the world’s leading cause of death.

25 Jul 2022

Researchers create a mobile app to calculate genetic risk for coronary artery disease

A Scripps Research team developed a smartphone app that can calculate users' genetic risk for coronary artery disease (CAD)-; and found that users at high risk sought out appropriate medication after using the app.

15 Mar 2022

Researchers employ genetic testing to determine the risk of developing cardiovascular disease

Dignity Health in Arizona is introducing the first research study in North America that will use genetic testing to pinpoint men and women who are at risk of developing a cardiovascular disease based on the composition of their DNA.

22 Feb 2022

Why is it Important to have Diverse Genomics Data in Science?

In this interview, we speak to Dr. Santiago Miriuka, CEO of MultiplAI Health, about the importance of having diverse genomics data in research.

From MultiplAI Health 17 Feb 2022

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

A University of South Florida Health (USF Health) preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

1 Feb 2022