Crohn’s Disease News and Research

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Strategies to Counter Postnatal Growth Retardation in Piglets

The metabolic basis of postnatal growth retardation (PGR) in piglets is not yet clear, but it is characterized by poor production performance, low feed conversion rate, and a high mortality rate.

4 Mar 2024

Exploring the Probiotic Potential of Fungi in Food Production

As detailed in a recent study, two fungi employed in food production exhibit promising probiotic properties that could help alleviate gut inflammation. This research sheds light on a potential avenue for creating novel probiotics.

27 Oct 2023

New Oral Probiotic Delivery System Keeps “Good” Bacteria Safe

Probiotics can help maintain a healthy gut microbiome or rebuild populations of “good bacteria” following an antibiotic course. They may now be utilized as a viable treatment strategy for certain intestinal diseases like Crohn’s disease.

22 Jun 2023

Genetic study emphasizes the significance of “balancing selection” in evolution

Nature can maintain various genetic features in balance as a species grows over millions of years, much like a merchant of old would do when balancing the weights of two distinct products on a scale.

23 Feb 2023

Non-immunosuppressive strategy mitigates immune-mediated intestinal diseases

The severity of immune-mediated intestinal diseases like graft-versus-host disease (GVHD) or inflammatory bowel disease is known to be associated with changes in the gut microbiome, but what causes such disruption in the microbial community is unknown.

3 Feb 2023

Detecting the extent of natural selection over time

Institut Pasteur, Université Paris Cité, the CNRS, and the Collège de France researchers have employed paleogenomics to trace 10,000 years of human immune system evolution. They examined the genomes of over 2,800 individuals who lived in Europe over the past 10 millennia.

From Institut Pasteur 18 Jan 2023

Simple inexpensive test determines the genetic susceptibility to PML

Four genetic mutations have been linked to progressive multifocal leukoencephalopathy (PML), a rare but sometimes fatal brain infection that can be provoked by dozens of FDA-approved drugs.

16 Dec 2022

Black death and the development of immune genes

The Black Death, which wiped off up to 50% of the European population in less than five years, was the single-worst mortality catastrophe in recorded history.

21 Oct 2022

Study shows how innate lymphoid cells may help to treat inflammatory bowel disease

A team of researchers at Sweden’s Karolinska Institutet studied how specific immune cells known as innate lymphoid cells (ILCs), which play a role in inflammatory bowel disease (IBD), evolve into mature cells.

18 Apr 2022

Antibodies play a major role in managing gut mycobiota, says study

According to recent research, antibody protection against harmful forms of fungi in the gut might be disrupted in some patients with Crohn’s disease.

25 Nov 2021

Enteric glial cells play a major role in gut immunity, says new study

Scientists from the Francis Crick Institute unraveled a basic role of glial cells in the nervous system of the gut in retaining a healthy intestine.

22 Oct 2021

New consortium of bacteria can be used to treat aggressive colitis in humanized mouse models

A new study reported in Nature Communications shows that a consortium of bacteria, developed to complement lacking or poorly represented functions in the imbalanced microbiome of inflammatory bowel disease (IBD) patients, inhibited and treated chronic immune-mediated colitis in humanized mouse models.

31 May 2021

High-fat, high-sugar diet reduces intestinal immune cell activity in mice

A team of researchers led by Thaddeus Stappenbeck discovered that a high-fat, high-sugar diet relates to reduced intestinal immune cell activity in mice.

20 May 2021

New genetic associations predict susceptibility to Takayasu arteritis

A team of international collaborators, headed by scientists from the University of Pittsburgh School of Medicine, have detected novel genetic associations that can estimate the susceptibility of individuals to Takayasu arteritis—a rare inflammatory disease.

14 Dec 2020