Cysteine News and Research

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Rare YKT6 Gene Variants Linked to New Neurological Disorder

A recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characterized by developmental delays along with severe progressive liver disease and a potential risk for liver cancer.

2 Apr 2024

Nature-Inspired Approach Accelerates Folding of Cysteine-Rich Peptides for Drug Discovery

Certain types of peptides and microproteins for drug discovery research can be made more efficiently and quickly using a reaction solvent that helps mimic nature's way.

25 Mar 2024

Researchers Reveal Evolutionary Origin of Mysterious Immune System Molecule in Humans

Biological systems can behave as siblings in several ways, including by borrowing something and never giving it back.

31 Jan 2024

Study Elucidates How Amino Acids Turn on Cell Growth Engine

Amino acids are the building blocks of life. We obtain them from the food we eat, and the body uses them to make proteins, which in turn are used for growth, development, and a multitude of other functions.

22 Dec 2023

Deciphering the Chemistry Behind Antibody Tetramerization

Novel insights into antibody aggregation are anticipated to pave the way for fresh avenues in both research and therapeutic applications.

11 Dec 2023

New Irreversible Inhibitor Overcomes Drug Resistance in Cancer Cells

The concept of irreversible inhibitors binding permanently to a target protein has garnered growing interest for potential applications in drug development.

30 Nov 2023

Exploring the Regulatory Mechanism and Physiological Significance of P62 Phosphorylation

Nuclear factor erythroid 2-related factor 2 (NRF2) is a master transcription factor with a role in maintaining oxidative stress response. It can be triggered by both redox-dependent and redox-independent pathways.

13 Jun 2023

Revealing an Unanticipated Mechanism for Chaperone-Mediated Ribosome Repair

Researchers have discovered that if oxidative stress destroys protein factories known as ribosomes, repair crews may go in to assist in repairing the damage so that production may restart rapidly.

26 Apr 2023

A Protein Domain Could Lead to New Treatments for COVID-19

Oak Ridge National Laboratory scientists exploring bioenergy plant genetics have made a surprising discovery: a protein domain that could lead to new COVID-19 treatments.

18 Apr 2023

Specialized Diet Stimulates a Unique Form of Programmed Cell Death

Glioblastoma is the most prevalent kind of adult brain tumor.

10 Apr 2023

Study reveals how chloroplast ATP synthase regulates ATP production in organisms

ATP, the compound essential for the functioning of photosynthetic organisms such as plants, algae, and cyanobacteria, is produced by an enzyme called "chloroplast ATP synthase" (CFoCF1).

22 Feb 2023

New insights into the mechanism underlying the immunomodulatory effects of polyphenols

PCB2DG, a polyphenol with anti-inflammatory properties, works by targeting and directly interacting with the major glutamine transporter protein, alanine serine cysteine transporter 2 (ASCT2), to inhibit the uptake of glutamine, an important amino acid found in the blood.

22 Feb 2023

Innovative cancer therapy options with new cell death mechanism

Researchers from The University of Texas MD Anderson Cancer Center have described a previously unrecognized type of cell death called disulfidptosis in a study that was published in Nature Cell Biology.

7 Feb 2023

Discovering H2O2 sensing capacity in plants that control immunity

All aerobic organisms produce the molecule hydrogen peroxide (H2O2). When present in low concentrations, it acts as a crucial secondary signal to control a variety of biological processes, including but not limited to plant-microbe interactions, abiotic stress tolerance, pollen tube growth, root hair formation, leaf cell expansion, and Casparian strip formation.

20 Oct 2022

Coral genome reveals cysteine biosynthesis pathways

Model animals, such as mice and fruit flies, have provided scientists with powerful insights into how cellular biology works. However, model animals are really just a guide, and it can be risky to generalize findings across animals from studying a selection of model organisms.

26 Sep 2022

Scientists link the function of specific domain of proteins to a cancer trigger in humans

Researchers at the Department of Energy's Oak Ridge National Laboratory have definitively linked the function of a specific domain of proteins important in plant-microbe biology to a cancer trigger in humans, knowledge that had eluded scientists for decades.

6 Jul 2022

Cysteine News and Research

Rare YKT6 Gene Variants Linked to New Neurological Disorder

Nature-Inspired Approach Accelerates Folding of Cysteine-Rich Peptides for Drug Discovery

Researchers Reveal Evolutionary Origin of Mysterious Immune System Molecule in Humans

Study Elucidates How Amino Acids Turn on Cell Growth Engine

Deciphering the Chemistry Behind Antibody Tetramerization

New Irreversible Inhibitor Overcomes Drug Resistance in Cancer Cells

Exploring the Regulatory Mechanism and Physiological Significance of P62 Phosphorylation

Revealing an Unanticipated Mechanism for Chaperone-Mediated Ribosome Repair

A Protein Domain Could Lead to New Treatments for COVID-19

Specialized Diet Stimulates a Unique Form of Programmed Cell Death

Study reveals how chloroplast ATP synthase regulates ATP production in organisms

New insights into the mechanism underlying the immunomodulatory effects of polyphenols

Innovative cancer therapy options with new cell death mechanism

Discovering H2O2 sensing capacity in plants that control immunity

Coral genome reveals cysteine biosynthesis pathways

Scientists link the function of specific domain of proteins to a cancer trigger in humans

ZDHHC18-mediated MDH2 palmitoylation upholds mitochondrial respiration and boosts ovarian cancer malignancy

Unusual partners aid new blood vessel development

High levels of sulfur volatiles in saliva make children dislike Brassica vegetables

Specific chemical feature of a key protein may lead to neurodegenerative diseases

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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