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Dietary Fiber Regulates Gut Microbiota and Improves Epithelial Cell Proliferation

A high-fiber diet is known to have several health benefits. Scientific studies point to protection against such diseases as cancer and diabetes.

25 Jul 2023

Study Uncovers Candidate Genes That may Drive Inflammatory Bowel Disease

A study of the genetic variation that makes mice more susceptible to bowel inflammation after a high-fat diet has identified candidate genes which may drive inflammatory bowel disease (IBD) in humans.

6 Jul 2023

Study Provides Evidence for Involvement of p53/p16/RB-E2F-DREAM Repressional Targets in Cellular Senescence

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Key elements of cellular senescence involve transcriptional repression of mitotic and DNA repair genes through the p53-p16/RB-E2F-DREAM complex."

14 Jun 2023

IgA Described as "Tuner" in Microbe Interaction Regulation

Throughout the world, IgA deficiency is considered to be the most common primary immune deficiency, but its presentation has continued to confuse researchers and physicians.

29 May 2023

Study Characterizes the Properties of MAIT Cells in Mouse Lung

A population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike.

26 May 2023

Ex Vivo Expansion of HSCs Using a Novel Culture System

Hematopoietic stem cells (HSCs) are immature blood cells found in the bone marrow that can be stimulated to develop into any type of blood cell.

25 May 2023

Targeting Respiratory Viral Infections with a New Immunotherapy Treatment

A researcher at the University of Central Florida College of Medicine has created a novel, more effective therapy for acute respiratory viral infections, a significant global cause of illness each year.

16 May 2023

Understanding How Cell-to-Cell Communication Networks Drive Pancreatic Cancer Development

Discussions of cancer often stress the genetic mutations that drive disease by altering the normal function of cellular proteins.

12 May 2023

Understanding How Interleukin-6 Contributes to Suppress Allergic Asthma and Atopy

The immune system has a biological telecommunications system -; small proteins known as interleukins that send signals among the leukocyte white blood cells to control their defense against infections or nascent cancer.

8 May 2023

New Insights on Cases of Post-Vaccine Heart Inflammation

Public health experts discovered an increase in cases of myocarditis, an inflammation of heart muscle, after the introduction of the new COVID-19 vaccinations two years ago, particularly in young males who had received mRNA vaccines.

8 May 2023

Role of Engineered E. coli in Sending Therapeutic Nanobodies to the Gut

Numerous bacterium types have taken up residence in humans. Currently, research is concentrated on genetically modifying these bacteria to increase their inherent therapeutic qualities.

5 Apr 2023

Effective backup mechanism ensures efficient antimicrobial responses in humans

In the human body, virus particles are identified by pattern recognition receptors (PRRs) either within or on the cell surface. When a receptor is activated, a signaling cascade is initiated, which results in the production and release of signaling molecules like interferons and cytokines.

14 Mar 2023

New insights into the mechanism underlying the immunomodulatory effects of polyphenols

PCB2DG, a polyphenol with anti-inflammatory properties, works by targeting and directly interacting with the major glutamine transporter protein, alanine serine cysteine transporter 2 (ASCT2), to inhibit the uptake of glutamine, an important amino acid found in the blood.

22 Feb 2023

Probiotic application shown to promote health and growth of piglets

This study is led by Prof. Heping Zhang (Inner Mongolia Key Laboratory of Dairy Biotechnology and Engineering, Inner Mongolia Agricultural University).

20 Feb 2023

Betalain-tomatoes confer anti-inflammatory effects against macrophages and murine colitis

Metabolic engineering is a field of plant biotechnology that seeks to genetically modify plant metabolic pathways to generate plant varieties with improved health benefits.

17 Feb 2023

Reversal of ADAR1 hyper-editing with small molecule inhibitor

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.

17 Feb 2023

Scientists develop new design principles to improve cancer vaccines

A new way to significantly increase the potency of almost any vaccine has been developed by researchers from the International Institute for Nanotechnology at Northwestern University.

1 Feb 2023

Improving cancer immunotherapies with bioengineered synthetic gene circuits

In two distinct studies, scientists show how synthetic biology can be used to address a challenging problem in cancer immunotherapy: the way immunotherapy-related approaches focused on the short-term killing of tumor cells could fail to eradicate tumors because tumor growth occurs on longer timescales.

19 Dec 2022

Major development in re-treatment with CAR T therapy

At the American Society of Hematology (ASH) Annual Meeting in 2022 (Abstract 2016), researchers from the Abramson Cancer Center at the University of Pennsylvania presented preliminary findings from an ongoing Phase I clinical trial demonstrating effective re-treatment with CAR T cell therapy for patients whose cancers relapsed after prior CAR T therapy.

12 Dec 2022

Gyros Protein Technologies adds Gyrolab® Biomarker Kits to expand range of ready-to-use kits and reagents

Gyros Protein Technologies AB today introduced Gyrolab® Human Cytokine Kit Reagents, the first in a range of new biomarker kits.

From Gyros Protein Technologies AB 30 Nov 2022