Cytokines News and Research

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Cytokine is a substance that is made by cells of the immune system. Some cytokines can boost the immune response and others can suppress it. Cytokines can also be made in the laboratory by recombinant DNA technology and used in the treatment of various diseases, including cancer.

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

Gene biomarker can distinguish between atopic dermatitis and psoriasis with 100% accuracy

Mount Sinai researchers have pinpointed a single gene biomarker, nitride oxide synthase 2 (NOS2) that can distinguish atopic dermatitis (AD) and psoriasis with 100 percent accuracy using adhesive tape strips, a non-invasive alternative to skin biopsy.

22 Jul 2020

Type 1 interferon deficiency in the blood could be a hallmark of severe COVID-19

Approximately 5% of people with Covid-19 progress to a severe or critical form, including the development of severe pneumonia that progresses to acute respiratory distress syndrome.

20 Jul 2020

Stem cell treatment could improve the quality of donor kidneys

New research has demonstrated that kidneys can be revived prior to transplantation by delivering a cell therapy directly to the organ.

From Newcastle University 15 Jul 2020

Researchers to develop new ways to prevent esophageal cancer

The incidence of esophageal adenocarcinoma has increased 8-fold over the past 50 years. This is one of the deadliest cancers, with a five-year survival rate of only 20 percent.

14 Jul 2020

Targeted radionuclide therapy creates a favorable tumor microenvironment in prostate cancer

Targeted radionuclide therapy has been found to create a favorable tumor microenvironment in prostate cancer that improves the effectiveness of immunotherapies.

14 Jul 2020

Study highlights the role of hematopoietic immune cells in gene regulation

More often, the human body is viewed as a “machine” containing specialized components: immune cells protect against pathogens, organs contribute physiological functions, and soft tissue and bones give structure.

6 Jul 2020

How upregulation of a single gene by SARs-CoV-2 can trigger cytokine storm

The SARS-CoV-19 virus initially has a limited capability to invade, attacking only one intracellular genetic target, the aryl hydrocarbon receptors (AhRs).

29 Jun 2020

Foodborne titanium dioxide nanoparticles impact gut microbiota in mice

A common food additive, recently banned in France but allowed in the U.S. and many other countries, was found to significantly alter gut microbiota in mice, causing inflammation in the colon and changes in protein expression in the liver, according to research led by a University of Massachusetts Amherst food scientist.

26 Jun 2020

Blocking A 'Jamming Signal' Can Unleash Immune System To Fight Tumors

Yale researchers have discovered a "jamming signal" that blocks a powerful immune system stimulant called interleukin-18 (IL-18) from reaching tumors.

25 Jun 2020

Dysfunctional placenta can contribute to Cornelia de Lange syndrome

Researchers have demonstrated that a dysfunctional placenta can play a formerly unknown role during the earliest phases of development in Cornelia de Lange.

17 Jun 2020

BCG vaccine elicits trained immunity in humans

A tuberculosis vaccine developed 100 years ago also makes vaccinated persons less susceptible to other infections.

16 Jun 2020

Deleting a key gene to create an immune cell with stronger anti-tumor activity

Using induced pluripotent stem cells (iPSCs) and deleting a key gene, researchers at University of California San Diego School of Medicine have created natural killer cells -- a type of immune cell -- with measurably stronger activity against a form of leukemia, both in vivo and in vitro.

From UC San Diego 12 Jun 2020

Researchers discover how cancer cells protect themselves from viruses

Researchers at the Francis Crick Institute have uncovered how cancer cells protect themselves from viruses that are harmful to tumors but not to healthy cells. These findings could lead to improved viral treatments for the disease.

2 Jun 2020

Adding A Blend Of Spices To A Meal May Help Lower Inflammation

Adding an array of spices to your meal is a surefire way to make it tastier, but new Penn State research suggests it may increase its health benefits, as well.

22 May 2020

New flow cytometry technique to quantify protein production in T-cells

A team of scientists from Hollings Cancer Center at the Medical University of South Carolina has developed a novel flow cytometry technique that can, for the first-time, quantify protein production in T-cells.

21 May 2020

Direct Control Of Dendritic Cells For Tracking And Immune Modulation

Dendritic cells are one of our bodies' first line of defense and are stationed like sentinels at all surfaces, as well as in most of our organs.

19 May 2020

Blood Cells Could Serve As A 'Thermometer' To Detect Breast Cancer

Immune system cells in the blood of breast cancer patients undergo alterations early in the disease course, according to a study.

18 May 2020

The microbiome regulates our immune system's fitness

Working alongside colleagues in Mainz, Bern, Hannover and Bonn, researchers from Charité - Universitätsmedizin Berlin, the Berlin Institute of Health and the German Rheumatism Research Center Berlin were able to show how the microbiome helps to render the immune system capable of responding to pathogens.

13 May 2020