Cytosine News and Research

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Highly efficient method to identify the genetic “switches” that control gene expression

Scientists have created a high-throughput method to help explain and regulate gene expression for the treatment of diseases like beta-thalassemia and sickle cell disease.

7 May 2021

“Chemical nose” smells vital variations in unusual folding of DNA structures

Small variations in the structure of DNA have been related to breast cancer and other diseases, but they have been incredibly hard to find so far.

6 May 2021

New nanopore sequencing tool can identify the existence of nucleobases

Nanopore technology has the potential to enable the development of portable, low-cost, small devices capable of real-time DNA sequencing.

4 May 2021

New computer algorithm helps identify tumors with 'mismatch repair deficiencies'

A new way to identify tumors that could be sensitive to particular immunotherapies has been developed using data from thousands of NHS cancer patient samples sequenced through the 100,000 Genomes Project.

27 Apr 2021

Mutant protein plays key role in Huntington’s disease

Back in 1993, researchers had discovered that Huntington’s disease is typically caused by a single mutated gene, known as HTT.

8 Mar 2021

Research shows magnesium contact ions stabilize complex folded structure of tRNA

In cells transfer RNA (tRNA) translates genetic information from the encoding messenger RNA (mRNA) for protein synthesis.

10 Dec 2020

New technology to unlock the secrets of plant genomes in high resolution

The genomes of all higher life forms are stored in the cell nucleus on chromosomes. Chromosomes are composed of strands of the DNA molecule.

22 Sep 2020

Researchers map DNA methylation changes to study developmental disorders

Researchers performed a study in which they created a total of 168 new maps of chemical marks on DNA strands, known as methylation, in developing mice.

30 Jul 2020

Genome editing technologies can help understand disease-associated genetic mutations

Scientists have developed novel genome-editing technology that could help understand disease-related genetic mutations based on C-to-G single base variations.

27 Jul 2020

Study shows how proteins prevent DNA replication errors

Two rereading proteins on the DNA assembly line collectively work as an emergency stop button to inhibit replication errors.

20 Jul 2020

New technique increases the precision of gene editing

A group of biomolecular engineers from Rice University has now identified a C-worthy method that significantly improves the precision of gene editing.

17 Jul 2020

New type of molecular editor can make precise changes in mitochondrial DNA

The genome in mitochondria -- the cell's energy-producing organelles -- is involved in disease and key biological functions, and the ability to precisely alter this DNA would allow scientists to learn more about the effects of these genes and mutations.

9 Jul 2020

Researchers develop a series of APOBEC-Cas9 fusion-induced deletion systems

Many small regulatory elements, including miRNAs, miRNA binding sites, and cis-acting elements, comprise only 5~24 nucleotides and play important roles in regulating gene expression, transcription and translation, and protein structure, and thus are promising targets for gene function studies and crop improvement.

1 Jul 2020

Scientists develop a new way to reactivate silenced genes

All cells in an organism are known to have the same genetic data but not all carry out the same function. This is because all the cells do not contain the same active genes.

19 May 2020