DNA Polymerase News and Research

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A DNA polymerase is an enzyme that catalyzes the polymerization of deoxyribonucleotides into a DNA strand. DNA polymerases are most well-known for their role in DNA replication, in which the polymerase "reads" an intact DNA strand as a template and uses it to synthesize the new strand. The newly-polymerized molecule is complementary to the template strand and identical to the template's original partner strand. DNA polymerases use a magnesium ion for catalytic activity.

Understanding TEFM's Role in mtDNA Stability

Mitochondrial deoxyribonucleic acid (mtDNA) is vital for cellular energy production and the overall functionality of cells.

6 Mar 2025

Cryo-EM Study Sheds Light on HSV Drug Resistance Mechanisms Through Protein Movement

All organisms -; from fungi to mammals -; have the capacity to evolve and adapt to their environments. But viruses are master shapeshifters with an ability to mutate greater than any other organism. As a result, they can evade treatments or acquire resistance to once-effective antiviral medications.

28 Aug 2024

Unlocking RNA Secrets: New Method Exposes Gene Expression's Hidden Hurdles

A new study demonstrates that a method may identify, for the first time, the frequency and precise location of a molecular occurrence known as "backtracking" across the genetic material (genome) of any species.

12 Feb 2024

Breakthrough in Single-Cell Genome Sequencing: New Method Reduces Bias and Expands Research Horizons

It has long been technically difficult to sequence the genome of a single bacterial cell due to the nearly impossible bias in the gene amplification stage of the process, making it difficult to produce a high-coverage genome sequence from precisely one bacterial cell.

25 Jul 2023

Ancient Virus-Like Transposons Found to Mediate Horizontal Gene Transfer in Worms

Scientists have known for decades that genes can be transferred from one species to another, both in animals and plants.

30 Jun 2023

Study Provides a New Picture of How Bacterial Cells Repair Faulty DNA

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

17 May 2023

A Rapid Method for the Quantitative Detection of miRNA

Researchers investigating the growth of a roundworm discovered a tiny RNA molecule that controlled the expression of specific genes in the early 1990s. This resulted in the discovery of microRNAs (miRNAs), which are now known to exist in all forms of life. These molecules, it turns out, play vital functions in a variety of biological processes.

26 Apr 2023

Cancer cells use new DNA repair mechanism to recover from next-generation cancer radiation therapy

A team of scientists led by Dr. Kei-ichi TAKATA from the Center for Genomic Integrity within the Institute for Basic Science (IBS), has discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy.

20 Mar 2023

Researchers propose a new fusion method in gene editing to reduce DNA sizes

Researchers who are working on CRISPR/Cas9-mediated gene-editing technology have developed a technique to boost editing performance by reducing DNA deletion sizes.

3 May 2022

Study provides insight into replication and transcription machinery of ranaviruses

Nucleo-cytoplasmic large DNA viruses (NCLDVs) of the genus Ranavirus (family iridoviridae) have been isolated from aquatic species such as reptiles, amphibians, and bony fish. Poikilotherms are at risk from these promiscuous infections.

21 Jan 2022

Scientists test the accuracy of enzymes that copy DNA under weightlessness

Researchers at Queen’s University boarded a modified Falcon 20 aircraft at Ottawa airport on May 22nd, 2019 as part of a scheduled “vomit comet” flight. In this mode of flight, the plane repeatedly climbs in a steep parabola to 8 km, alternating with a freefall descent.

2 Dec 2021

Study pinpoints the mutational hotspots in DNA

Recent research at the University of Bath reveals that tangles in unwound DNA can develop mutational hotspots in the genomes of bacteria.

From University of Bath 21 Oct 2021

Scientists analyze the molecular machinery of poxviruses at an atomic level

Poxviruses have found a unique way of translating their genes into proteins in the infected organism. A team of researchers from Würzburg shows for the first time how the molecular machinery involved works at an atomic level.

24 Sep 2021

Human cells can convert RNA sequences into DNA

Cells include machinery that replicates DNA into a new set, and this, in turn, develops into a newly formed cell.

15 Jun 2021

Refreshers develop new DNA sequencing method

An international research team headed by Michal Hocek of the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) and Charles University and Ciara K. O'Sullivan of Universitat Rovira i Virgili (URV) in Spain have developed a novel method for labeling DNA, which in the future can be used for sequencing DNA by means of electrochemical detection.

18 May 2021

DNA Polymerase News and Research

Understanding TEFM's Role in mtDNA Stability

Cryo-EM Study Sheds Light on HSV Drug Resistance Mechanisms Through Protein Movement

Unlocking RNA Secrets: New Method Exposes Gene Expression's Hidden Hurdles

Breakthrough in Single-Cell Genome Sequencing: New Method Reduces Bias and Expands Research Horizons

Ancient Virus-Like Transposons Found to Mediate Horizontal Gene Transfer in Worms

Study Provides a New Picture of How Bacterial Cells Repair Faulty DNA

A Rapid Method for the Quantitative Detection of miRNA

Cancer cells use new DNA repair mechanism to recover from next-generation cancer radiation therapy

Researchers propose a new fusion method in gene editing to reduce DNA sizes

Study provides insight into replication and transcription machinery of ranaviruses

Scientists test the accuracy of enzymes that copy DNA under weightlessness

Study pinpoints the mutational hotspots in DNA

Scientists analyze the molecular machinery of poxviruses at an atomic level

Human cells can convert RNA sequences into DNA

Refreshers develop new DNA sequencing method

Study discovers how some proteins ensure repair of errors introduced during DNA replication

Study reveals novel dimension in the study of protein-protein interactions

Polβ enzyme prevents breakdown of DNA in the hippocampus region

Scientists identify complex enzyme that protects cells from constant DNA damage

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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