Dopamine News and Research

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Dopamine is a hormone and neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors — D1, D2, D3, D4 and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine has many functions in the brain, including important roles in behavior and cognition, motor activity, motivation and reward, inhibition of prolactin production (involved in lactation), sleep, mood, attention, and learning. Dopaminergic neurons (i.e., neurons whose primary neurotransmitter is dopamine) are present chiefly in the ventral tegmental area (VTA) of the midbrain, substantia nigra pars compacta, and arcuate nucleus of the hypothalamus.
Scientists identify mystery protein that explains the origins of Parkinson's Disease

Scientists identify mystery protein that explains the origins of Parkinson's Disease

Genetically modified tomato can provide a new source of Parkinson’s disease drug

Genetically modified tomato can provide a new source of Parkinson’s disease drug

Gene variations that regulate dopamine levels may influence the mobility of elders

Gene variations that regulate dopamine levels may influence the mobility of elders

Dopamine and serotonin found to be involved in perception, cognitive capacities

Dopamine and serotonin found to be involved in perception, cognitive capacities

Cocaine addiction: Impact of genetic mutations elucidated

Cocaine addiction: Impact of genetic mutations elucidated

Stem cells can repair parkinson's-damaged circuits in mouse brains

Stem cells can repair parkinson's-damaged circuits in mouse brains

Protein in the pancreas protects beta-cells from high-fat diet induced stress

Protein in the pancreas protects beta-cells from high-fat diet induced stress

Study highlights the role of brain astrocyte cells in Parkinson's disease pathology

Study highlights the role of brain astrocyte cells in Parkinson's disease pathology

Switching off 'master regulator' may offer neuroprotection from Parkinson's-related damage

Switching off 'master regulator' may offer neuroprotection from Parkinson's-related damage

New fluorescent probe to detect damaged mitochondria could help treat neurodegenerative disorders

New fluorescent probe to detect damaged mitochondria could help treat neurodegenerative disorders

How sweet-taste perception changes with age

How sweet-taste perception changes with age

Single-nucleus RNA sequencing helps compare transcriptional responses to acute cocaine

Single-nucleus RNA sequencing helps compare transcriptional responses to acute cocaine

Molecular dynamic simulations may contribute to structure-based drug design

Molecular dynamic simulations may contribute to structure-based drug design

Solving A Parkinson's Disease Puzzle Through Protein Design

Solving A Parkinson's Disease Puzzle Through Protein Design

New protein design could help in drug discovery for Parkinson’s disease

New protein design could help in drug discovery for Parkinson’s disease

Study reveals structure of an activated dopamine receptor

Study reveals structure of an activated dopamine receptor

Mice study reveals new therapeutic strategy for slowing down Huntington's disease

Mice study reveals new therapeutic strategy for slowing down Huntington's disease

Synthetic molecule suppresses drug cravings with fewer side effects

Synthetic molecule suppresses drug cravings with fewer side effects

Making opioids safer and more effective

Making opioids safer and more effective

Autoimmunity Plays A Role In Parkinson's Disease

Autoimmunity Plays A Role In Parkinson's Disease