Dopamine News and Research

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Dopamine is a hormone and neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors — D1, D2, D3, D4 and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine has many functions in the brain, including important roles in behavior and cognition, motor activity, motivation and reward, inhibition of prolactin production (involved in lactation), sleep, mood, attention, and learning. Dopaminergic neurons (i.e., neurons whose primary neurotransmitter is dopamine) are present chiefly in the ventral tegmental area (VTA) of the midbrain, substantia nigra pars compacta, and arcuate nucleus of the hypothalamus.
Study identifies two types of brain cells that play a key role in creating memories

Study identifies two types of brain cells that play a key role in creating memories

New study uncovers potential driver of Parkinson’s disease

New study uncovers potential driver of Parkinson’s disease

Three proteins as potential new therapeutic targets in movement disorders

Three proteins as potential new therapeutic targets in movement disorders

New computational method could help quickly screen billions of drug compounds

New computational method could help quickly screen billions of drug compounds

Experts investigate link between COVID-19 and Parkinson’s disease

Experts investigate link between COVID-19 and Parkinson’s disease

Dopamine may play a key role in shaping female songbirds' auditory preference

Dopamine may play a key role in shaping female songbirds' auditory preference

Study identifies a novel role for regulatory protein Bach1 in Parkinson's disease

Study identifies a novel role for regulatory protein Bach1 in Parkinson's disease

Exploring cell and gene based therapies for Parkinson’s disease

Exploring cell and gene based therapies for Parkinson’s disease

Old habit-controlling neurons may also play a key role in learning new tricks

Old habit-controlling neurons may also play a key role in learning new tricks

Experimental small molecule could help treat Parkinson’s disease in future

Experimental small molecule could help treat Parkinson’s disease in future

Gene therapy may be safe and effective in treating AADC deficiency

Gene therapy may be safe and effective in treating AADC deficiency

Study discloses neuroprotective properties of aromatic turmerone and its derivatives

Study discloses neuroprotective properties of aromatic turmerone and its derivatives

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Children with rare genetic disorder experience dramatic improvements in a gene therapy trial

Children with rare genetic disorder experience dramatic improvements in a gene therapy trial

Genetically encoded sensor helps detect hallucinogenic substances

Genetically encoded sensor helps detect hallucinogenic substances

Study identifies single protein key to regulating sex differences in Parkinson’s disease

Study identifies single protein key to regulating sex differences in Parkinson’s disease

Study finds an amyloid link between melanoma and Parkinson’s disease

Study finds an amyloid link between melanoma and Parkinson’s disease

Dopamine-releasing brain cells shed light on Parkinson’s disease

Dopamine-releasing brain cells shed light on Parkinson’s disease

New sensor can rapidly detect RNA and DNA molecules

New sensor can rapidly detect RNA and DNA molecules

Scientists identify mystery protein that explains the origins of Parkinson's Disease

Scientists identify mystery protein that explains the origins of Parkinson's Disease

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