Drug Delivery News and Research

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Drug delivery is a term that refers to the delivery of a pharmaceutical compound into the body. Most common methods of delivery include the preferred non-invasive oral (through the mouth), nasal, pneumonial (inhalation), and rectal routes. Much research is now focussing on nanotechnology as a drug delivery method.

Genetically Modified iPS Cell Applications for Fabry Disease

iPS cells have had a significant impact on biology and medicine, and they are expected to increase regenerative medicine. Clinical trials with various cell types derived from iPS cells have been performed since 2014 when a sheet of retinal pigment epithelial cells obtained from iPS cells was transplanted into patients with age-related macular degeneration.

4 Jul 2023

New Oral Probiotic Delivery System Keeps “Good” Bacteria Safe

Probiotics can help maintain a healthy gut microbiome or rebuild populations of “good bacteria” following an antibiotic course. They may now be utilized as a viable treatment strategy for certain intestinal diseases like Crohn’s disease.

22 Jun 2023

Assembled DNA Nanostructures Without the Use of Magnesium Yield Greater Stability

Researchers at the University at Albany’s RNA Institute have demonstrated a new approach to DNA nanostructure assembly that does not require magnesium.

7 Jun 2023

Scientists Integrate Multiple Therapeutic Approaches to More Effectively Target Brain Metastatic Melanomas

Acting as a team, twin stem cells activate the immune system to suppress tumor growth and prolong survival in representative preclinical models.

1 Jun 2023

New Platform for Production of Synthetic Nitrated Proteins in Bacteria

In this study, the researchers focused on para-nitro-L-phenylalanine (pN-Phe), a non-standard amino acid that is neither one of the twenty standard amino acids nor been observed in nature.

24 May 2023

Study Finds Methylated CD Derivatives as Effective Stabilizers for Supersaturated Drugs

In the medicine market, most newly introduced drugs and drug candidates show poor water solubility, which prevents their absorption in the body. This, in turn, limits their therapeutic efficiency.

16 May 2023

Researchers Develop a System to Deliver Antioxidants to the Mitochondria

A new drug delivery system delivers an antioxidant directly to mitochondria in the liver, mitigating the effects of oxidative stress.

11 May 2023

Role of Engineered E. coli in Sending Therapeutic Nanobodies to the Gut

Numerous bacterium types have taken up residence in humans. Currently, research is concentrated on genetically modifying these bacteria to increase their inherent therapeutic qualities.

5 Apr 2023

Designing a Lipid Nanoparticle to Safely Deliver mRNA to the Pancreas

Therapeutics that use mRNA-;like some of the COVID-19 vaccines-;have enormous potential for the prevention and treatment of many diseases.

4 Apr 2023

SMART researchers develop the world's first microneedle-based drug delivery technique for plants

Researchers from the Disruptive & Sustainable Technologies for Agricultural Precision (DiSTAP) Interdisciplinary Research Group (IRG) of Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, and their collaborators from Temasek Life Sciences Laboratory (TLL) and Massachusetts Institute of Technology (MIT), have developed the first-ever microneedle-based drug delivery technique for plants.

14 Mar 2023

Study identifies previously unknown cell types that drive the onset of osteoarthritis

A Michigan Medicine study has identified a new potential target for treating osteoarthritis – a debilitating joint disease that affects over 31 million Americans and is a leading cause of disability worldwide.

10 Mar 2023

Digital microfluidics as the optimal technology for bacterial protocol advances

The February 2023 issue of SLAS Technology contains a set of four original research articles and one review article covering digital microfluidics (DMF), cryopreservation, colorectal cancer research and other laboratory automation technology.

17 Feb 2023

New optical tool controls bacterial electrical signaling

Bacteria, like neurons in human brains, utilize electricity to interact and react to environmental cues. Scientists have now developed a strategy to regulate this electrical signaling in bacteria to better comprehend antibiotic resistance.

From The University of Warwick 15 Feb 2023

Researchers develop a sustainable two-step process to upcycle organic carbon waste

When nature designed lignin -; the fibrous, woody material that gives plants their rigid structure -; it didn't cut any corners. Incredibly slow to break down, lignin is so sturdy and long lasting that it is resistant to bacteria and rot.

1 Feb 2023

Intracellular drug delivery using a novel nano transporter

The effectiveness of a novel nano molecule as a drug delivery system has been examined in a recent study by the University of Barcelona.

From University of Barcelona 13 Jan 2023

New biobattery could power ingestible cameras in the small intestine

Tech companies have developed many devices that work outside the body, such as cell phones, smart watches, tablets and hundreds of others. Inside the body, though? That's obviously trickier for several reasons, but power for a device is a big one.

14 Dec 2022

Novel liposomal nanovaccines strongly activate cellular immunity

Cancer immunotherapies, such as immune checkpoint inhibition therapy, have been attracting attention in recent years as new methods for treating cancer.

2 Nov 2022

Radical theory examines how charged macromolecules self-assemble

Researchers from the University of Massachusetts Amherst recently reported in the Proceedings of the National Academy of Sciences that uniformly charged macromolecules, or molecules like proteins or DNA, which contain a large number of atoms all with the same electrical charge, can self-assemble into very large structures.

27 Sep 2022

How can High-Content Screening accelerate Drug Discovery?

As part of our SLAS Europe 2022 coverage, we speak to Professor Jeremy Simpson from the University College Dublin about the role high-content screening can play in accelerating drug discovery.

From Society for Laboratory Automation and Screening (SLAS) 6 Jul 2022

Stanford scientists develop fingertip-sized millirobots to improve targeted drug delivery

If you've ever swallowed the same round tablet in hopes of curing everything from stomach cramps to headaches, you already know that medicines aren't always designed to treat precise pain points.

17 Jun 2022