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Microbial communities with auxotrophs more likely to have increased drug tolerance, study finds

Research from the Francis Crick Institute has revealed a key mechanism which increases tolerance to drugs amongst microbial communities.

22 Mar 2022

Research highlights how genome editing tool CRISPR knocks off genes in cancer cells

Researchers have created a novel method that allows them to correlate particular genes to complex tumor properties at a size and resolution that has never been achievable.

21 Mar 2022

Non-steroidal anti-inflammatory drugs help to enhance crop genome editing tools, study says

According to plant scientists at RIKEN, a class of non-steroidal anti-inflammatory drugs might be useful for studying the molecular processes underlying plant immunity.

21 Mar 2022

Novel method to sneak large drug-carrying biological molecules into cells

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a novel method of delivering drugs into human cells using large biological molecules, by first encasing them in a protein-based microdroplet.

From Nanyang Technological University Singapore (NTU Singapore) 17 Mar 2022

Researchers develop an antibody as a tool for opening the blood-brain barrier

The brain is composed of billions of neurons-; vulnerable cells that require a protective environment to function properly.

17 Mar 2022

Novel “green” synthesis of drug for inflammatory bowel disease

Steroids and antibody drugs are currently used to treat inflammatory bowel disease (IBD), which is characterized by chronic inflammation of the digestive tract.

16 Mar 2022

INTEGRA’s VIAFLO 384 proves indispensable in neurodegeneration research

Scientists at Rejuveron Vascular Therapeutics AG, a company specializing in the development of therapies to tackle neurodegeneration, are using INTEGRA’s VIAFLO 384 handheld electronic pipette to accelerate their research.

From INTEGRA Biosciences 16 Mar 2022

Researchers create a mobile app to calculate genetic risk for coronary artery disease

A Scripps Research team developed a smartphone app that can calculate users' genetic risk for coronary artery disease (CAD)-; and found that users at high risk sought out appropriate medication after using the app.

15 Mar 2022

New method could create a promising vehicle for vaccine delivery against SARS-CoV-2

Physicists, chemists and immunologists at McMaster University have teamed up to modify red blood cells to transport viral agents which can safely trigger the immune system to protect the body against SARS-CoV-2, creating a promising new vehicle for vaccine delivery.

14 Mar 2022

Proximity-dependent biotinylation helps analyze protein interaction

Protein degraders, which cause target proteins to break down, are thought to be the “next-generation drugs” because they may eliminate disease-causing proteins from cells.

9 Mar 2022

Reversing the destructive aging process in egg cells to increase fertility in older women

Throughout much of the world, increasing numbers of women are delaying having their first child until they are in their late thirties, and even into their forties.

9 Mar 2022

Study takes a deep dive into the molecular biology of the brain in bipolar disorder patients

In a comprehensive study involving one of the largest-ever samples of post-mortem brains, scientists at the Lieber Institute for Brain Development, in collaboration with researchers at the Johns Hopkins School of Medicine and Bloomberg School of Public Health, have pinpointed significant differences in gene expression in two specific regions of the brains of hundreds of patients who had bipolar disorder.

8 Mar 2022

Study provides insights into the biological mechanisms behind the severe form of COVID-19

A total of 16 novel genetic variations linked to severe Covid-19 have been discovered, including ones that affect blood coagulation, immunological response, and inflammation severity.

8 Mar 2022

Researchers develop new method to detect the role of enigmatic gene sequences

Karolinska Institute researchers have recently developed new high-precision techniques for determining the role of these noncoding sequences.

7 Mar 2022

CNIC study uncovers a nuclear import mechanism essential for organ growth and development

Scientists at the Centro Nacional de Investigaciones Cardiovasculares have identified a nuclear import mechanism essential for organ growth and development. Manipulation of this mechanism has potential applications in the control of organ growth and organ regeneration.

4 Mar 2022

Researchers show how hotspot maps can detect structures contributing to compounds’ selectivity

The quantity of structural data available on protein drug targets keeps growing.

4 Mar 2022

Two distinct classes of stem cells drive treatment resistance in patients with myelodysplastic syndromes

Researchers from The University of Texas MD Anderson Cancer Center discovered that treatment resistance in patients with myelodysplastic syndromes (MDS) is caused by two distinct classes of stem cells and identified possible therapeutic approaches that target these cells.

3 Mar 2022

Capturing the mechanisms underlying evolvability in a new framework

All life evolves: microorganisms can become resistant to drugs, viruses evade our vaccines, and species may adapt to climate change.

3 Mar 2022

Researchers optimize a route for two-step synthesis of antiviral plant protectant

Plant viruses are of great variety and harm. Virus disease pandemics and epidemics were estimated to have a global economic impact in the tens of billions of dollars.

3 Mar 2022

Researchers find an epigenetic adaptation showing resistance to targeted therapy in T cell leukemia

Although gene mutations can result in drug resistance, scientists in the Perelman School of Medicine at the University of Pennsylvania have found a vital, non-genetic version that could also boost resistance to targeted treatment in T cell leukemia, which is a kind of blood cell cancer.

3 Mar 2022

Drugs News and Research

Microbial communities with auxotrophs more likely to have increased drug tolerance, study finds

Research highlights how genome editing tool CRISPR knocks off genes in cancer cells

Non-steroidal anti-inflammatory drugs help to enhance crop genome editing tools, study says

Novel method to sneak large drug-carrying biological molecules into cells

Researchers develop an antibody as a tool for opening the blood-brain barrier

Novel “green” synthesis of drug for inflammatory bowel disease

INTEGRA’s VIAFLO 384 proves indispensable in neurodegeneration research

Researchers create a mobile app to calculate genetic risk for coronary artery disease

New method could create a promising vehicle for vaccine delivery against SARS-CoV-2

Proximity-dependent biotinylation helps analyze protein interaction

Reversing the destructive aging process in egg cells to increase fertility in older women

Study takes a deep dive into the molecular biology of the brain in bipolar disorder patients

Study provides insights into the biological mechanisms behind the severe form of COVID-19

Researchers develop new method to detect the role of enigmatic gene sequences

CNIC study uncovers a nuclear import mechanism essential for organ growth and development

Researchers show how hotspot maps can detect structures contributing to compounds’ selectivity

Two distinct classes of stem cells drive treatment resistance in patients with myelodysplastic syndromes

Capturing the mechanisms underlying evolvability in a new framework

Researchers optimize a route for two-step synthesis of antiviral plant protectant

Researchers find an epigenetic adaptation showing resistance to targeted therapy in T cell leukemia

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