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Solving A Parkinson's Disease Puzzle Through Protein Design

Dopamine is a neurotransmitter involved in everything and the receptors have been a longstanding target for treating disorders like Parkinson's disease.

17 Jun 2020

New protein design could help in drug discovery for Parkinson’s disease

The neurotransmitter dopamine plays a vital role in everything, starting from motor control to higher cognitive functions, arousal, motivation, sexual gratification, and reinforcement.

12 Jun 2020

Researchers develop intracellular biopsy to isolate targeted miRNAs from living cells

MicroRNAs, are attracting interest relating to human diseases because variations in the expression of miRNAs are often associated with abnormal functions.

11 Jun 2020

Study reveals structure of an activated dopamine receptor

Dopamine, a chemical that sends messages between different parts of the brain and body, plays a key role in a variety of diseases and behaviors by interacting with receptors on cells.

11 Jun 2020

TU Dresden study uncovers enzyme essential for intestinal epithelial differentiation

The intestinal epithelium is the inner layer of the intestinal wall, which separates host tissue from the intestinal microbiota.

9 Jun 2020

Cryo-electron microscopy helps visualize PANX1 protein at near-atomic level

For the first time, researchers from Van Andel Institute have explained the near-atomic level structure of a molecular route that has crucial roles to play in the regulation of blood pressure, cell death, inflammation, and human development.

4 Jun 2020

Research team discovers proteins that regulate interorganelle communication

Korea Brain Research Institute (KBRI headed by Suh Pann-ghill) announced on the 2nd that the joint research team of KBRI (team led by Dr. Mun Ji-young), Seoul National University, and Pohang University of Science and Technology discovered the proteins that engage in the formation of MAM, which is the cellular signaling hub.

4 Jun 2020

Study shows how ocean virus captures the metabolism of carbon-storing bacteria

Below the surface of the ocean, a virus is stealing the metabolism of the most abundant organism present on Earth. That might be attractive to those who breathe above the ocean’s surface.

28 May 2020

X-ray experiments reveal antibody to block entry of SARS-CoV-2

As scientists across the globe race to develop a vaccine against SARS-CoV-2, the coronavirus that causes COVID-19, an international team led by Davide Corti at Vir Biotechnology and David Veesler at the University of Washington has been working around the clock on a complementary approach - identifying neutralizing antibodies that could be used as a preventative treatment or as a post-exposure therapy.

20 May 2020

New study sheds light on enigmatic giant microbes

In the recent past, researchers have uncovered giant viruses in some of the most enigmatic locations in the world, from Siberia’s thawing permafrost to locations unknown under the Antarctic ice.

11 May 2020

New algorithm links large-scale membrane changes to molecular level simulations

Researchers have devised a new technique that integrates different levels of resolution in a computer simulation of biological membranes.

11 May 2020

New technique reveals the proliferation and genetic exchange of bacteria

Researchers have made a breakthrough interpretation of the way bacteria move and carry out genetic exchange—that may possibly result in the development of novel antimicrobial drugs.

From University of Exeter 7 May 2020

Researchers Develop Chemistry Needed To Create Marijuana Breathalyzer

Chemists have reported the key chemical discovery necessary for the creation of a small, electronic marijuana breathalyzer.

7 May 2020

Researchers design novel cell culture model of human intestine to study COVID-19

Scientists have identified that the coronavirus SARS-CoV-2, known to cause COVID-19, infects intestinal cells and undergo proliferation there.

4 May 2020

Researchers study the evolution of multidrug-resistant bacteria

Although antibiotics are known to save lives, their use also supports the evolution and spread of antibiotic-resistant strains.

29 Apr 2020

Reef fish flip a genetic switch in response to warming seas

Reef fish species uniquely respond to climate change, with some more vulnerable than others.

23 Apr 2020

Study reveals the mechanism used by tuberculosis bacteria for their growth

The structure of a protein that plays a role in importing vitamin B12 into the cells of a tuberculosis (TB)-causing bacterium has been revealed by scientists from the Netherlands, Russia, the United States, and Sweden.

23 Apr 2020

Biophysicists uncover new features of molecular elevator

Biophysicists from the Moscow Institute of Physics and Technology and the University of Groningen in the Netherlands have visualized a nearly complete transport cycle of the mammalian glutamate transporter homolog from archaea.

21 Apr 2020

Discovery marks a critical step toward developing new anti-cancer drugs

A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified the binding site where drug compounds could activate a key braking mechanism against the runaway growth of many types of cancer.

21 Apr 2020