Enzyme News and Research

RSS

Small Molecule Restores TERT Levels to Combat Aging-Related Decline

Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring 'youthful' levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models.

24 Jun 2024

Detecting Auto-Antibodies for Early Identification of High-Risk COVID-19 Cases

Researchers recently discovered that auto-antibodies against their type 1 interferons, crucial immunological signaling proteins, were present in some COVID-19 patients.

20 Jun 2024

Enzymes Replace Cyanide in Eco-Friendly Nitrile Synthesis

If the household cleaner emits a lemon-like odor, it may be due to a nitrile called citronellyl nitrile. Chemical-resistant gloves, superglue, and active pharmaceutical ingredients are all made with these adaptable chemical nitrile groups.

19 Jun 2024

Multimodal Imaging Reveals Heterogeneity in Amyloid Plaques

Alzheimer's disease (AD), which affects millions of people globally, is still one of the most difficult and common neurodegenerative conditions.

19 Jun 2024

Ancestry Bias can Cause CRISPR Screens to Miss Cancer Dependencies

CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and grow.

17 Jun 2024

Virus-Like Nanoparticles Facilitate DNA Release and Host Reproduction in Streptomyces

Viruses are ubiquitous in the environment, and organisms have developed various mechanisms to counter their threat.

12 Jun 2024

Water-Soluble Bacterial Enzyme Could Enable Rapid Screening of Potential Antibiotics

A bacterial enzyme called histidine kinase is a promising target for new classes of antibiotics. However, it has been difficult to develop drugs that target this enzyme, because it is a "hydrophobic" protein that loses its structure once removed from its normal location in the cell membrane.

11 Jun 2024

CSHL Researchers Reveal New Protein Networks in RNA Splicing Regulation

Bodybuilders and cellular mechanisms agree generating protein is a heavy lift. To complete the task, cells rely on complexes called spliceosomes.

11 Jun 2024

Engineered Enzyme Boosts Gene Editing Efficiency for Potential Cystic Fibrosis Treatment

Researchers at the Broad Institute of MIT and Harvard have enhanced a gene-editing technology, enabling it to efficiently insert or substitute entire genes in the genome of human cells.

11 Jun 2024

Dundee Scientists Reveal Inner Workings of PINK1 Molecular Switch in Parkinson's Disease

Scientists at the University of Dundee have uncovered the inner relay of a molecular switch that protects the brain against the development of Parkinson's disease.

10 Jun 2024

Study Unveils Key Mechanism of Telomere Maintenance by CST–Polα/Primase

The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, resulting in telomere disorders with serious health consequences.

6 Jun 2024

AMPLON Simplifies DNA Amplification for Diverse Medical Applications

A team of researchers from Case Western Reserve University School of Medicine has created a novel method for target DNA sequence amplification, testing, and analysis.

6 Jun 2024

Researchers Advance Single-Molecule DNA Sequencing Techniques

In recent years, technologies that allow scientists to investigate a person's DNA at single-molecule resolution have greatly increased the knowledge of the human genome, microbiome, and the genetic basis of disease.

5 Jun 2024

CRISPR/Cas Biosensors Address Sensitivity and Specificity Challenges in Detection

The mechanisms of CRISPR-Cas-based biosensors.

5 Jun 2024

New Trojan Horse Virus Potentially Linked to Severe Toxoplasmosis

An international team led by researchers at the University of Toronto has found a new RNA virus that they believe is hitching a ride with a common human parasite.

3 Jun 2024

Engineered DNA PROTAC Shows Promise for p53-R175H Mutant Cancers

A synthetic bicomponent compound specifically targets and eliminates a mutant protein associated with multiple forms of cancer.

30 May 2024

Structural Insights into a Novel Gene-Editing Tool

Yutaro Shuto, Ryoya Nakagawa, and Osamu Nureki of the University of Tokyo conducted collaborative research to ascertain the spatial organization of different processes within a unique gene-editing instrument known as “prime editor.”

30 May 2024

Integrative genomic study identifies two new potential drug targets in Mycobacterium tuberculosis

Researchers used existing whole genome sequences of M. tuberculosis and conducted a pangenomic analysis to identify potential drug targets.

28 May 2024

Multiplexed Orthogonal Base Editors for Precise Mutation Modeling

The human genome consists of around 3 billion base pairs and humans are all 99.6% identical in their genetic makeup.

23 May 2024

Sonification Reveals Hidden Patterns in Protein Folding Dynamics

By converting their data into sounds, scientists discovered how hydrogen bonds contribute to the lightning-fast gyrations that transform a string of amino acids into a functional, folded protein.

21 May 2024

Enzyme News and Research

Small Molecule Restores TERT Levels to Combat Aging-Related Decline

Detecting Auto-Antibodies for Early Identification of High-Risk COVID-19 Cases

Enzymes Replace Cyanide in Eco-Friendly Nitrile Synthesis

Multimodal Imaging Reveals Heterogeneity in Amyloid Plaques

Ancestry Bias can Cause CRISPR Screens to Miss Cancer Dependencies

Virus-Like Nanoparticles Facilitate DNA Release and Host Reproduction in Streptomyces

Water-Soluble Bacterial Enzyme Could Enable Rapid Screening of Potential Antibiotics

CSHL Researchers Reveal New Protein Networks in RNA Splicing Regulation

Engineered Enzyme Boosts Gene Editing Efficiency for Potential Cystic Fibrosis Treatment

Dundee Scientists Reveal Inner Workings of PINK1 Molecular Switch in Parkinson's Disease

Study Unveils Key Mechanism of Telomere Maintenance by CST–Polα/Primase

AMPLON Simplifies DNA Amplification for Diverse Medical Applications

Researchers Advance Single-Molecule DNA Sequencing Techniques

CRISPR/Cas Biosensors Address Sensitivity and Specificity Challenges in Detection

New Trojan Horse Virus Potentially Linked to Severe Toxoplasmosis

Engineered DNA PROTAC Shows Promise for p53-R175H Mutant Cancers

Structural Insights into a Novel Gene-Editing Tool

Integrative genomic study identifies two new potential drug targets in Mycobacterium tuberculosis

Multiplexed Orthogonal Base Editors for Precise Mutation Modeling

Sonification Reveals Hidden Patterns in Protein Folding Dynamics

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Latest in Genomics