Enzyme News and Research

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Cre-controlled CRISPR makes conditional gene inactivation more easier

To discover the function of a gene researchers turn it off and observe the consequences. Often genes have multiple functions that differ depending on a tissue and age.

24 Feb 2021

New gene-editing technique allows for pre-programming of sequential edits

Researchers from the University of Illinois Chicago have discovered a new gene-editing technique that allows for the programming of sequential cuts -- or edits -- over time.

24 Feb 2021

Study reveals a major genetic risk factor for severe COVID-19

In 2020, a research team demonstrated that a significant genetic risk factor for severe COVID-19 infection was inherited from Neanderthals.

17 Feb 2021

Study suggests a way to improve immunotherapy by altering immune cells’ access to sugar

Cancer cells and immune cells share something in common: They both love sugar. Sugar is an important nutrient. All cells use sugar as a vital source of energy and building blocks. For immune cells, gobbling up sugar is a good thing, since it means getting enough nutrients to grow and divide for stronger immune responses. But cancer cells use sugar for more nefarious ends.

17 Feb 2021

Gene-based blood test may predict treatment success in people with metastatic melanoma

A test that monitors blood levels of DNA fragments released by dying tumor cells may serve as an accurate early indicator of treatment success in people in late stages of one of the most aggressive forms of skin cancer, a new study finds.

15 Feb 2021

Innovative system allows complete study of SARS-CoV-2 mutant spectrum by ultrasequencing

Researchers have designed a program that allows the complete study of the SARS-CoV-2 mutant spectrum by ultrasequencing.

15 Feb 2021

Electrochemical sensor for rapid detection of multiple sepsis biomarkers in whole blood

Many life-threatening medical conditions, such as sepsis, which is triggered by blood-borne pathogens, cannot be detected accurately and quickly enough to initiate the right course of treatment.

15 Feb 2021

Enzyme in fruit fly larvae plays key role in waking up brain stem cells

Researchers studying an enzyme in fruit fly larvae have found that it plays an important role in waking up brain stem cells from their dormant 'quiescent' state, enabling them to proliferate and generate new neurons.

12 Feb 2021

New technique reveals natural structure of large enzyme complex

A new technique has revealed the natural structure of specifically massive and complex enzymes.

11 Feb 2021

Research may help better understand the biochemistry underlying catalysis in cells

Investigators from the Institute of Scientific and Industrial Research at Osaka University, together with the Hiroshima Institute of Technology, have announced the discovery of a new protein that allows an organism to conduct an initial and essential step in converting amino acid residues on a crosslinked polypeptide into an enzyme cofactor.

11 Feb 2021

Scientists use new approach to avert drug resistance in glioblastomas

In far too many cases over the years, scientists have discovered promising new cancer treatments, only to report later that the tumor cells found ways to become resistant. These disappointing results have made overcoming drug resistance a major goal in cancer research.

11 Feb 2021

Researchers program genome tool to target specific histone proteins

If finding a needle in a haystack is hard enough, then one should try finding a particular molecule on the needle.

11 Feb 2021

Unusual DNA folding leads to higher mutation rates

DNA sequences that can fold into shapes other than the classic double helix tend to have higher mutation rates than other regions in the human genome.

10 Feb 2021

Study finds the brain is changed by caffeine in utero

New research finds caffeine consumed during pregnancy can change important brain pathways that could lead to behavioral problems later in life.

10 Feb 2021

Study reveals genetic factors linked to COVID-19 susceptibility in people with Down syndrome

A study reveals the genetic factors that may expose or protect people with Down syndrome from SARS-CoV-2 infection, as well as the prognosis of COVID-19.

9 Feb 2021

New technology could improve antibody testing in a broad range of diseases

A global team of researchers has developed a new strategy for fast and reliable antibody tests, which can quantify the immune response induced by vaccination and reveal the timeline and stage of pathogen infection.

5 Feb 2021

Researchers discover hydrogen-producing enzyme group that resists oxygen attack

Hydrogen-producing enzymes are beacons of hope in biohydrogen research. However, they are so vulnerable to oxygen in the air that it has not been possible to exploit their potential on a larger scale.

3 Feb 2021

Yale scientists discover novel metabolic gatekeeper mechanism for leukemia

In a new study led by Yale Cancer Center, researchers have discovered a novel metabolic gatekeeper mechanism for leukemia. This mechanism depends on a molecule called PON2, which could lead to a new treatment for the disease. The findings were published online today in the Proceedings of the National Academy of Sciences (PNAS).

2 Feb 2021

Researchers identify a new compound for creating a new class of diabetes drugs

A new study headed by the Ohio State University Wexner Medical Center and the College of Medicine has found a new compound that could form the base for creating a new class of diabetes drugs.

28 Jan 2021

Two enzymes drive pre-cancer stem cells into malignancy

Since stem cells can continually self-regenerate, making more stem cells, and differentiate into many different specialized cell types, they play an important role in our development and health.

27 Jan 2021