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Innovative Method Accelerates Discovery of New Drugs by Harnessing the Power of Ribosomes

A research team led by University of California, Irvine scientists has developed an innovative method for quickly and efficiently creating vast collections of chemical compounds used in drug discovery by harnessing the power of ribosomes, the molecules found in all cells that synthesize proteins and peptides.

24 Aug 2023

PS Gene Editing Rebuilds Lost Neural Connections in Brain Disorder

A new study from the University of Minnesota is the first to show that gene therapy can mend neural connections in people with Hurler syndrome, a rare hereditary brain condition.

22 Aug 2023

New Synthetic Catalyst Breaks Down Cellulose: Study

Yan Zhao gestured toward the trees outside his campus window on a rainy afternoon.

22 Aug 2023

Understanding Early Agroforestry Development in Tropical Regions

One of the most serious threats to soil biodiversity and ecological functioning is land use change. The most significant threat to biodiversity is tropical deforestation to construct monoculture cash tree plantations.

17 Aug 2023

Bacteria Have Complex Circadian Clocks, Study Finds

Bacteria make up more than 10% of all living things but until recently we had little realization that, as in humans, soil bacteria have internal clocks that synchronize their activities with the 24-hour cycles of day and night on Earth.

7 Aug 2023

Leveraging Nature's Blueprint: The Impact of Directed Evolution in Protein Engineering

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Miguel Alcalde, a Research Professor at the CSIC, about directed evolution in enzymology and the wider biotechnology sector.

From Society for Laboratory Automation and Screening (SLAS) 4 Aug 2023

Gut Hormone Plays a Vital Role in Maintaining the Balance of Fungi in the Digestive System of Mammals

Peptide YY (PYY), a hormone produced by gut endocrine cells that was already known to control appetite, also plays an important role in maintaining the balance of fungi in the digestive system of mammals, according to new research from the University of Chicago.

4 Aug 2023

Amazon Dark Earth for Accelerated Tree Growth

A study published in the journal Frontiers in Soil Science asserts that a type of soil known as terra preta da Amazônia, or Amazon dark earth (ADE), encourages quicker growth of trees and improves their development in terms of quality.

2 Aug 2023

Researchers Develop New Photoenzymatic Method to Produce Chiral Amines

Using energy from light to activate natural enzymes can help scientists create new-to-nature enzymatic reactions that support eco-friendly biomanufacturing -; the production of fuels, plastics, and valuable chemicals from plants or other biological systems.

1 Aug 2023

New Gene Editing Technique Reduces Chalkiness in Rice

As global temperatures continue to rise, maintaining the quality and yield of crops adapted to lower temperatures will increasingly become a challenge.

31 Jul 2023

Analyzing DNA Damage-Induced NF-κB Targeted by Novel Small Molecule Inhibitors

Chemotherapy and radiotherapy aim to destroy cancer cells by inducing DNA double-strand breaks – damage that, once inflicted, usually causes the cells to die. But damage to a cell's genetic material also activates a signaling pathway called IKK/NF-κB that helps prevent cell death, thus limiting the success of these treatments in patients.

28 Jul 2023

Towards Artificial Photosynthesis with Engineering of Protein Crystals in Bacteria

In-cell engineering can be a powerful tool for synthesizing functional protein crystals with promising catalytic properties, show researchers at Tokyo Tech.

26 Jul 2023

In-Cell Engineering Proves to be a Powerful Tool for Synthesizing Functional Protein Crystals

In-cell engineering can be a powerful tool for synthesizing functional protein crystals with promising catalytic properties, show researchers at Tokyo Tech.

26 Jul 2023

Essential Bacterial Signaling Autoproteolysis in C. thermocellum

Sensing and communicating with the extracellular environment are both aspects of transmembrane signaling.

24 Jul 2023

New Process by Which Enzymes Help Prevent Heart Damage in Chemotherapy Patients Identified

Researchers at the University of Illinois Chicago have identified a process by which enzymes can help prevent heart damage in chemotherapy patients.

21 Jul 2023

Scientists Identify Key Regulator of Bacterial Cell Wall Remodeling

The bacterial cell wall must be constantly remodeled in order to grow and divide. This involves the close coordination of lytic enzymes and peptidoglycan synthesis.

20 Jul 2023

Rensselaer Professor Receives $400,000 Grant to Study Deep Sea Enzymes

Rensselaer Polytechnic Institute's Catherine Royer, Constellation Chair Professor of Bioinformatics and Biocomputation at the Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS) and professor of biological sciences, has received a grant of over $400,000 from the National Science Foundation to investigate enzymes from organisms living in deep sea environments.

14 Jul 2023

Researchers Uncover Astonishing Diversity of Protein Structures Previously Unexplored

The astounding variety of protein structures and their folds in nature has been further illuminated by a ground-breaking discovery. Researchers wanted to know how much of the huge range of potential protein structures nature had examined.

12 Jul 2023

Scientists Develop Method to Create Artificial Allosteric Sites in Protein Complexes

According to a recently published research paper by a team of scientists, a groundbreaking approach has been developed to create artificial allosteric sites (where by binding an effector molecule, activity at the distal active site is regulated) in protein complexes.

7 Jul 2023

New Method Reveals How Hepatitis C Virus Evades Immune System

With a new method for examining virus samples researchers from the University of Copenhagen have solved an old riddle about how Hepatitis C virus avoids the human body's immune defenses.

6 Jul 2023