Epigenetics News and Research

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Epigenetics is the study of chemical reactions that influence gene expression, through activation or deactivation of genes at specific times and locations.

NSL Complex Regulates Intraciliary Transport Genes in Multiple Cell Types

The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown in both fruit flies and mammals to regulate the expression of thousands of genes. Abrogation of the NSL genes causes the organism to die, which gives rise to the complex’s unusual name.

28 Aug 2023

Researchers Shed Light on Complex Interplay Between Taste Perception and Immune Function

A bitter taste in the mouth is often a symptom or side effect of illness, which may be the result of how the body reacts to pathogens. A new study published in iScience, by Hong Wang, PhD, an Associate Member at the Monell Chemical Sense Center, and colleagues sheds light on the mechanisms involved in the complex interplay between taste perception and immune function.

25 Aug 2023

Epstein-Barr Virus Epigenome Targeted for Potential Cancer Treatment

Now, scientists at The Wistar Institute have discovered a potential target for gastric cancers associated with Epstein-Barr Virus; study results were published in the journal mBio.

23 Aug 2023

Researchers Show How Different Taste Cells are Affected by Inflammation Using Gene Mapping Tool

A bitter taste in the mouth is often a symptom or side effect of illness, which may be the result of how the body reacts to pathogens.

23 Aug 2023

Researchers Lead Innovative Studies on Mammalian Aging and Life Span

Scientists at UCLA David Geffen School of Medicine and UCLA Health led an international research team that published two articles detailing changes in DNA – changes that researchers found are shared by humans and other mammals throughout history and are associated with life span and numerous other traits.

11 Aug 2023

GEMINI Test Uses Genome-Wide Sequencing to Detect Cancer

Novel blood testing technology being developed by researchers at the Johns Hopkins Kimmel Cancer Center that combines genome-wide sequencing of single molecules of DNA shed from tumors and machine learning may allow earlier detection of lung and other cancers.

7 Aug 2023

The Mechanism of Immune Memory Development

The memory of the immune system depends on distinctive epigenetic traits and a particular 3D arrangement of the DNA in the nucleus of memory cells, allowing for rapid activation of these cells, according to a team of researchers from the Erasmus University Medical Center, the Centre for Genomic Regulation (CRG), and the Josep Carreras Leukaemia Research Institute.

12 Jul 2023

Study Links Timing of Childhood Adversity With Epigenetic Patterns in Adolescents

Childhood adversity-;circumstances that threaten to a child's physical or psychological well-being--has long been associated with poorer physical and mental health throughout life, such as greater risks of developing cardiac disease, cancer, or depression.

14 Jun 2023

Study Finds Place of Transcription Start Often Determines the Place of Transcription End

Each gene in the human DNA has a start and an endpoint. It is critical to correctly define the gene's extremities to make functional proteins. Much study has been conducted to identify what determines when, where, and at which place on the DNA a gene “starts.”

16 May 2023

New Approach Could Power the Development of Advanced Cell Therapies

A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods.

2 May 2023

Molecular Mechanisms That Maintain the Tissue Specificity of PKMzeta

The protein PKMzeta has been strongly associated with long-term memory formation.

19 Apr 2023

Trinity Scientists Discover New Mechanisms Involved in Establishing Cellular Identity

A team of scientists led by those in Trinity College Dublin has discovered new mechanisms involved in establishing cellular identity, a process that ensures the billions of different cells in our bodies do the correct job.

10 Apr 2023

Two subtypes of cells that produce insulin discovered

A team of scientists from the Van Andel Institute and the Max Planck Institute for Immunobiology and Epigenetics uncovered two unique subtypes of insulin-producing beta cells, or ß cells, each having important traits that could potentially be used to better understand and treat Type 1 and Type 2 diabetes.

30 Mar 2023

Epigenetic fingerprinting helps trace the origin of animal products

Food analysis laboratories can provide an answer to questions like “Was the salmon for dinner really caught wild or did it come from aquaculture? What to make of the alleged ‘biolabel quality’ of the shrimp for the seafood salad? And was the chicken for the Sunday roast really allowed to spend its life in the open air?” to a limited extent.

30 Mar 2023

Study presents top 100 research questions facing plant science

Without plants, we'd have no air to breathe or food to eat, yet plant science lingers in the shadowy wings while other fields take center stage.

20 Mar 2023

Study links neutral maternal behavior toward infants with epigenetic change in children

Adding evidence to the importance of early development, a new study links neutral maternal behavior toward infants with an epigenetic change in children related to stress response.

3 Mar 2023

Stress response in mom leads to epigenetic change in children

Adding evidence to the importance of early development, a new study links neutral maternal behavior toward infants with an epigenetic change in children related to stress response.

2 Mar 2023

Epigenetics and the symbiosis between trees and fungi

To share nutrients and enhance their capacity for environmental adaptability, tree roots frequently collaborate with fungi. Although this interaction is mutually beneficial (namely, ectomycorrhizae), the biological mechanisms at play have not yet been completely analyzed.

23 Feb 2023

Importance of epigenetic regulation in the recovery of T cells

In stem cell transplants for leukemia treatment, the patient’s hematopoietic system is removed and replaced with hematopoietic cells from donors.

10 Feb 2023

Researchers address new quantitative approaches to better define cancer epigenetic landscape

It is now widely understood that cancer is a disease of acquired defects in genes and gene function.