Flow cytometry is a technique for counting and examining microscopic particles suspended in a stream of fluid. It allows simultaneous multiparametric analysis of the physical and/or chemical characteristics of single cells flowing through an optical and/or electronic detection apparatus.
In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.
Cerba Research recently expanded. Our U.S. Immuno-Oncology Center of Excellence allows us to provide even more comprehensive, integrated central lab services, specialty lab and biomarker solutions, and diagnostic services worldwide.
Mitochondria are known as the powerhouses of the cell, generating the energy that's needed to fuel the functions that our cells carry out.
Are prematurely aged or overworked stem cells a significant factor in chronic lung disease? Findings of a study just released in STEM CELLS Translational Medicine (SCTM) say this is likely so.
A group of clinical experts and international scientists have revealed a novel cell type in human skin that contributes to inflammatory skin diseases like psoriasis (PSO) and atopic dermatitis (AD).
Researchers published an article that represents the transmission electron microscopy (TEM) and flow cytometry study of A-549 (human lung carcinoma) cellular uptake of Pr3+:LaF3 nanoparticles.
Malignant tumor cells undergo mechanical deformation more easily than normal cells, allowing them to migrate throughout the body. The mechanical properties of prostate cancer cells treated with the most commonly used anti-cancer drugs have been investigated at the Institute of Nuclear Physics of the Polish Academy of Sciences in Cracow.
A team of scientists at Nagoya University in Japan has invented an extremely versatile DNA fluorescent dye called “Kakshine".
Human blood contains several different components, including plasma, red blood cells (RBCs), white blood cells (WBCs), and platelets.
Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years.
Immunology experts have collaborated to use their groundbreaking research techniques to put people’s response to COVID-19 disease under the microscope.
To identify new potential therapeutic targets for SARS-CoV-2, a team of scientists at the New York Genome Center, New York University, and the Icahn School of Medicine at Mount Sinai, performed a genome-scale, loss-of-function CRISPR screen to systematically knockout all genes in the human genome.
A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD), a life-threatening condition that can arise after hematopoietic stem cell transplantation (HSCT) for treatment of liquid cancers such as leukemia.
From pollen forecasting, honey analysis and climate-related changes in plant-pollinator interactions, analysing pollen plays an important role in research.
Each year, nearly 120 million units* of donated blood flow from donor veins into storage bags at collection centres around the world.
Switching off a molecular "master regulator" may protect the brain from inflammatory damage and neurodegeneration in Parkinson's disease, reports a study published today in Nature Neuroscience.
T cells are the immune soldiers at the frontlines of the battle with infiltrating pathogens that seek to cause disease. A new study published in Nature Biomedical Engineering describes a novel label-free imaging technique that can differentiate active T cells from those off duty.
A team of researchers, headed by Kanazawa University, has demonstrated that a tiny fish can potentially stop painful genetic and metabolic bone diseases. The study was recently published in the Communications Biology journal.
Targeted radionuclide therapy has been found to create a favorable tumor microenvironment in prostate cancer that improves the effectiveness of immunotherapies.
Researchers have studied over 30,000 variants of genetic sequences to determine which traits of mRNA can enhance translational efficiency.