Flow cytometry is a technique for counting and examining microscopic particles suspended in a stream of fluid. It allows simultaneous multiparametric analysis of the physical and/or chemical characteristics of single cells flowing through an optical and/or electronic detection apparatus.
Single-cell analysis is an effective biomedical technique used to identify unusual cell populations, monitor cell development and differentiation, comprehend disease causes, and design individualized therapies, but it generates massive amounts of data that can be challenging to handle.
In experiments with mice and humans, a team led by Johns Hopkins Medicine researchers says it has identified a particular intestinal immune cell that impacts the gut microbiome, which in turn may affect brain functions linked to stress-induced disorders such as depression.
Space travel has always tested the human body by the effects of the new conditions of altered gravity on biological systems.
Until recently, cells were typically counted on a reusable quartz hemocytometer. With the advent of automated cell counters 12-15 years ago, disposable slides became widespread.
A new biomedical research tool that enables scientists to measure hundreds of functional proteins in a single cell could offer new insights into cell machinery.
Infections caused by primary immunodeficiency diseases (PID) can be persistent and life-threatening. More than 450 PIDs have been identified, yet diagnosing them quickly and accurately remains a difficulty.
In latest years, messenger RNA—the DNA’s close relative in the complex process of turning a string of genetic blueprints into a properly functioning organism—has gotten a lot of attention in the scientific and medical community.
The dysfunction of memory CD8 + T cell can not be reverted by successful clearance of hepatitis C virus (HCV) after direct-acting antivirals (DAA) therapy, increasing the risk of reinfection with HCV.
Flow cytometry is a powerful and complex technology used to count, sort or measure characteristics of cells and to detect biomarkers.
Non-neutralizing antibodies may also be crucial in giving protection against COVID-19, according to a recent study from Lund University in Sweden.
As any parent knows, infants are prone to getting respiratory infections. But a new study shows that the infant immune system is stronger than most people think and beats the adult immune system at fighting off new pathogens.
A next-generation technology that allows the study of protein expression at the single-cell level and the location of the cells within the tumor microenvironment (TME) was feasible and provided information on the benefit of adding the immune checkpoint inhibitor atezolizumab (Tecentriq) to chemotherapy as neoadjuvant treatment for patients with early high-risk and locally advanced triple negative breast cancer (TNBC), according to results presented at the San Antonio Breast Cancer Symposium, held December 7-10, 2021.
In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.
Cerba Research recently expanded. Our U.S. Immuno-Oncology Center of Excellence allows us to provide even more comprehensive, integrated central lab services, specialty lab and biomarker solutions, and diagnostic services worldwide.
Mitochondria are known as the powerhouses of the cell, generating the energy that's needed to fuel the functions that our cells carry out.
Are prematurely aged or overworked stem cells a significant factor in chronic lung disease? Findings of a study just released in STEM CELLS Translational Medicine (SCTM) say this is likely so.
A group of clinical experts and international scientists have revealed a novel cell type in human skin that contributes to inflammatory skin diseases like psoriasis (PSO) and atopic dermatitis (AD).
Researchers published an article that represents the transmission electron microscopy (TEM) and flow cytometry study of A-549 (human lung carcinoma) cellular uptake of Pr3+:LaF3 nanoparticles.
Malignant tumor cells undergo mechanical deformation more easily than normal cells, allowing them to migrate throughout the body. The mechanical properties of prostate cancer cells treated with the most commonly used anti-cancer drugs have been investigated at the Institute of Nuclear Physics of the Polish Academy of Sciences in Cracow.
A team of scientists at Nagoya University in Japan has invented an extremely versatile DNA fluorescent dye called “Kakshine".