Fluorescent Protein News and Research

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Study provides a feasible tool to evaluate vesicular endocytosis of NPC1L1-cargos and cholesterol absorption

Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is a well-established risk factor for atherosclerotic cardiovascular disease.

29 Mar 2023

Newest variant of mScarlet3 to help track protein movements in living cells

Biologists frequently utilize a method to figure out why a cell divides, secretes hormones, or sends a signal to another cell. They attach colored lights to the proteins of interest so that they can see their motions and interactions in living cells under a microscope.

28 Mar 2023

Using a programmable control switch to deliver therapeutic RNA molecules to target cells

Using an RNA sensor, MIT engineers have designed a new way to trigger cells to turn on a synthetic gene.

17 Mar 2023

Using data from Sanger sequencing to quantify of genetic variants in bacterial cultures

Genetic variations, such as mutations, recombinations, or transpositions occur naturally in cultured microorganisms and are often considered nonneutral mutations.

7 Mar 2023

Using ultrasound waves to move genetically engineered cells

Let's say you needed to move an individual cell from one place to another. How would you do it? Maybe some special tweezers? A really tiny shovel?

24 Feb 2023

Reversal of ADAR1 hyper-editing with small molecule inhibitor

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.

17 Feb 2023

Study suggests new strategies for controlling plant biochemistry

Plant biochemists at the U.S. Department of Energy's Brookhaven National Laboratory have discovered a new level of regulation in the biochemical "machinery" that plants use to convert organic carbon derived from photosynthesis into a range of ring-shaped aromatic molecules.

12 Jan 2023

Small fluorescent protein helps researchers to capture deeper, more precise biomedical images

Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have designed a small fluorescent protein that emits and absorbs light that penetrates deep into biological tissue.

7 Dec 2022

Genetic timestamping tracks the fate of plasma cells over time

Vaccines function by effectively producing immune cells that live for a long time, frequently for decades. These immune cells form a protective barrier that prevents or reduces re-infection, as well as a memory that enables one to identify an old invader, such as a virus, and eliminate it before it causes disease.

1 Nov 2022

The science behind gene activation in plants

Researchers explain how a particular variety of GFP can be utilized to allow people to visually observe protein synthesis in this study.

10 Oct 2022

Visualizing subcellular structures with the aid of a brilliant fluorescent protein

The RIKEN discovery of a fluorescent protein produced from a Japanese jellyfish that maintains its brightness even under intense light could have significant positive effects on fluorescence imaging of biological samples.

3 Oct 2022

Antibiotics deplete intestinal flora and weaken the immune response

According to a recent study conducted by scientists at Emory University in Atlanta, the administration of broad-spectrum antibiotics in mice with malignant melanoma, an aggressive type of skin cancer, expedited their metastatic bone growth.

12 Sep 2022

Circadian clocks involve primarily in fat cell growth

According to two studies conducted by researchers at Weill Cornell Medicine, the circadian clocks that keep the body and its cells synchronized to the 24-hour day-night cycle are severely disrupted.

9 Aug 2022

Novel fluorescent probe likely to help decode neuronal talking

Numerous cells, including neurons, depend on the intracellular messenger molecule cyclic adenosine monophosphate (cAMP) to function. It does this by encouraging axon growth and maintaining neuronal communication.

15 Jul 2022

Research may lead to new therapies for metabolic disorders and other diseases

Researchers at UT Southwestern have uncovered a molecular path that allows cells to detect when their lipid supplies are running low, triggering a flurry of activity that avoids starvation.

23 May 2022

Researchers analyze the effect of dopamine on gene activity and addiction

North Carolina State University researchers have shown that neuron-like cells produced from human stem cells may be used to examine alterations in the neurological system linked to addiction.

10 May 2022

New technique for better visualizing the CNS fibroblasts

The central nervous system (CNS) consists of several types of cells having varied specialized functions.

7 Apr 2022

Researchers discover how an “accordion effect” is vital for switching off genes

In a study that changes the fundamentals of what researchers know about gene silencing, WEHI researchers demonstrated how an “accordion effect” is key to switching off genes.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 7 Apr 2022

Research shows that fruit flies sperm are no more male entirely after mating

According to recent research on fruit flies, the sperm becomes half feminine after mating, which was previously thought to be purely male.

25 Mar 2022

Confocal laser scanning microscopy captures high-resolution 3D images of cell division in microalgae

Cell division ensures growth or renewal and is thus vital for all organisms. However, the process differs somewhat in animals, bacteria, fungi, plants, and algae.

8 Mar 2022