Gastrointestinal Tract News and Research

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Real-Time Imaging Reveals the Dynamics of Microbial Colonization in the Gut

A research team led by Carnegie Science's Will Ludington, Karina Gutiérrez-García, and Kevin Aumiller has identified genes that allow a beneficial bacterial species to colonize specific areas of the gastrointestinal tract.

12 Dec 2024

Understanding Gut Inflammation Through RNA Sequencing

This study creates a comprehensive atlas of gastrointestinal cell types, revealing how stem cell-derived INFLAREs drive inflammation in chronic diseases.

29 Nov 2024

Novel Fungal Commensal Shaping Mouse Immune Responses

Researchers from Weill Cornell Medicine have found a fungus in the stomach of mice that may provide a clue to the evolution of fungi in the gastrointestinal tract.

28 Nov 2024

Discovery of Large Tandem Duplications Opens New Avenues for Cancer Treatment

Cancer researchers at the University of Chicago and the University of California, San Francisco (UCSF) have discovered that mutations in certain genes can lead to the accumulation of DNA errors, resulting in a specific type of genetic change known as large tandem duplications (TDs) that can arise from the collision of two critical cellular processes: transcription and DNA replication.

21 Nov 2024

Novel Cellular Atlas of the Human Gastrointestinal Tract

Spatial and single-cell data from 1.6 million cells have been combined to produce the most complete cell map of the human stomach to date.

21 Nov 2024

New Imaging Technique Reveals Microbial Interactions

Numerous species of oral bacteria have been identified by scientists, but there are still many unanswered questions about how they interact.

19 Nov 2024

Progress in Ingestible Microbiome Sampling Pill Technology

At the Tufts University School of Engineering, significant progress has been made in creating a tiny device that is comparable in size to a vitamin pill and can be swallowed to sample the entire population of microorganisms in a person's gastrointestinal tract.

13 Jun 2024

Study Reveals How Sweet Taste Receptor Regulates Blood Sugar and Insulin

The rich research portfolio of the Monell Chemical Senses Center on sweet taste goes way back: Monell scientists were one of four teams in 2001 that found and described the mammalian sweet taste receptor – TAS1R2-TAS1R3.

20 May 2024

Role of Candidalysin in Gut Microbiome Dynamics

The fungus Candida albicans commonly inhabits the human gastrointestinal tract. This versatile species can switch between existing as single-celled yeast and multicellular hyphae to adjust to its surroundings.

22 Mar 2024

Adhesion GPCR Mayo Plays Key Role in Midgut Development of Fruit Flies

Adhesion GPCRs belong to the large family of G protein-coupled receptors (GPCRs). There are about 700 variants in humans, which are responsible for sensory impressions, hormonal cycles, controlling the cardiovascular system and more.

18 Mar 2024

EPFL Scientists Develop Platform for Orally Available Cyclic Peptide Drugs

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy.

29 Dec 2023

Gut Microbes Key to Alleviating Canine Inflammatory Bowel Disease

Researchers at Oregon State University – Cascades have led a study that suggests gut microbes discovered in wild wolves could hold the solution to relieving a prevalent gastrointestinal ailment in domestic dogs.

3 Oct 2023

Study Highlights Critical Development Window During Which Racial Differences in Gut Microbiome Emerge

Early social and environmental exposures can have large and lasting effects on child development and adult health.

18 Aug 2023

Study Shows How Sensory Neurons Control Gastrointestinal Tracts

Gastrointestinal and digestive issues impact roughly 3 million people across the United States alone, and that number is growing.

4 Aug 2023

Mast Cells May Help Humans Avoid Harmful Antigens

Mast cells, which are part of the immune system, are still a puzzle. Mast cells function as a sensor that signifies the animals to avert antigens, including harmful allergens, and thus safeguard themselves from health-threatening inflammatory reactions, according to researchers at the German Cancer Research Center (DKFZ). The research was published in the journal Nature.

13 Jul 2023

Extraoral Bitter Taste Receptors Serve as Endogenous Sensors for Bile Acids

Taste receptors for bitter substances are not only observed on the tongue but also on cells outside of the oral cavity.

5 Jul 2023

Fructose is Needed for Enhanced Egg Production in Fruit Flies, Study Reveals

To many people, the sugars we eat may seem like a luxury that can do more harm than good. But now, researchers from Japan have discovered that in insects, dietary sugars play a key role in reproduction.

25 May 2023

Activated B Cells in Gastrointestinal Tract Contribute to the Development of Liver Cancer

Inflammatory fatty liver disease (NASH, non alcoholic steatohepatitis ) and the resulting liver cancer are driven by autoaggressive T cells. Scientists from the German Cancer Research Center (DKFZ) now show what ist behind this destructive behavior. I

24 May 2023

Understanding How Diet may Influence the Gut Microbiota Structure

We know that eating a healthy diet affects body weight, cholesterol levels, and heart health. A new study from the University of Illinois focuses on another component: the role of diet in supporting a healthy gastrointestinal microbiota.

5 May 2023

Diet Plays a Bigger Role in Shaping Intestinal Microbiota Composition Than Defensins

Researchers at Umeå University, Sweden, have found that among the many factors that shape the intestinal microbiota composition, diet has a much stronger impact than defensins, which are intestinal defence molecules produced by the body.

4 May 2023