Gastrointestinal Tract News and Research

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Immune cell biomarker may help identify patients at risk for graft-versus-host disease

A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD), a life-threatening condition that can arise after hematopoietic stem cell transplantation (HSCT) for treatment of liquid cancers such as leukemia.

8 Oct 2020

Polyphenolic compound extracted from blueberry can treat inflammatory bowel disease

Different plants and their products contain “bioactive” components that can reduce human diseases.

25 Sep 2020

Allergic immune responses protect against bacterial infections

Allergy is one of the most common diseases in Europe, it is estimated that more than 150 million Europeans suffer from recurring allergies and by 2025 this could have increased to half of the entire European population.

10 Sep 2020

Treatments targeting the gut microbiome can protect space travelers from adverse health problems

Space travelers who spend long periods of time in space can experience health problems, such as adverse effects on metabolism, and immunity.

9 Sep 2020

Developing new fluorescent metal sensors to explore the gastrointestinal tract

A University of Houston researcher is developing a new set of metal sensors that will be able to function in the gastrointestinal tract, a low oxygen environment, to examine how gut bacteria respond when trace metal nutrients, like iron and zinc, are thrown out of balance either through diet or disease.

20 Aug 2020

Greater gut microbial diversity in kidney cancer patients linked to better treatment outcomes

Physicians at City of Hope, working in collaboration with scientists at Translational Genomics Research Institute (TGen), have found that greater gut microbial diversity in patients with metastatic kidney cancer is associated with better treatment outcomes on Food and Drug Administration-approved immunotherapy regimens.

20 Aug 2020

SIDT1 in the mammalian stomach mediates absorption of dietary miRNAs

In a new study published in Cell Research, Chen-Yu Zhang's group at Nanjing University School of Life Sciences, China, reports that SIDT1 in the mammalian stomach mediates host uptake of dietary and orally administered microRNAs (miRNAs), thus exerting biological functions in the host.

18 Aug 2020

Gut dysbiosis in people with Huntington's disease may offer a potential target for future treatment

A world first clinical study of the gut microbiome in people with Huntington's disease (HD) has found that it is not just a disease of the brain, but also of the body.

7 Aug 2020

Researchers comprehensively describe the 'human tissue virome atlas'

Human-resident microbes can influence both health and disease. Investigating the microbiome using next-generation sequencing technology has revealed examples of mutualism and conflict between microbes and humans.

22 Jul 2020

Emerging hydrogel material could improve delivery of oral drugs

An emerging hydrogel material with the capacity to degrade and spontaneously reform in the gastrointestinal tract could help researchers develop more effective methods for oral drug delivery.

From Lehigh University 20 Jul 2020

Study shows gut microbiota can predict the development of type 2 diabetes

The individual mix of microorganisms in the human gastrointestinal tract provides vital clues as to how any future incidence of type 2 diabetes can be predicted, prevented and treated. This is demonstrated in a population study led from the University of Gothenburg. Sweden.

14 Jul 2020

Compound in pickled capers can activate proteins required for bodily processes

A compound commonly found in pickled capers has been shown to activate proteins required for normal human brain and heart activity, and may even lead to future therapies for the treatment of epilepsy and abnormal heart rhythms.

14 Jul 2020

Newly synthesized peptides show promise for treating gastrointestinal disorders

Thanks to the interesting group of trefoil factor peptides, both industry and research could usher in better treatments for chronic disorders.

8 Jul 2020

Study shows raw milk harbors antimicrobial-resistant genes

According to a new study, raw cow’s milk sold in U.S. retail stores can harbor a large amount of antimicrobial-resistant genes if stored at room temperature.

From The University of California, Davis 1 Jul 2020

Cloning stem cells to create new treatments for Crohn's disease

For over a decade Wa Xian, research associate professor of biology and biochemistry at the University of Houston Stem Cell Center, has been perfecting technology for cloning stem cells.

19 Jun 2020

Using organic electrochemical transistor to measure extracellular electron transfer in bacteria

Scientists at Laboratory of Organic Electronics, Linköping University, have developed an organic electrochemical transistor that they can use to measure and study in fine detail a phenomenon known as extracellular electron transfer in which bacteria release electrons.

18 Jun 2020

High sodium intake affects health of gut microbiome

Particularly in females with untreated hypertension, reducing salt intake to what's considered a healthier level appears to be good for both their gut microbiome and their blood pressure, scientists report.

10 Jun 2020

Understanding protein-coding gene's role in IBD

A protein-coding gene associated with autoimmune diseases such as Crohn's disease and ulcerative colitis, collectively referred to as inflammatory bowel disease, or IBD, will be the focus of new research in the School of Medicine at the University of California, Riverside.

9 Jun 2020

Do Chemical Pollutants Increase the Risk of Celiac Disease?

Do chemical pollutants increase the risk of celiac disease? AZoLifeSciences spoke to Abigail Gaylord and Dr. Jeremiah Levine to find out.

From New York University (NYU) 3 Jun 2020

Gut-brain connection may help treat neurological diseases

Researchers are not clear whether mucus is the first line of defense against bad bacteria in the human gut.

2 Jun 2020