Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

Researchers identify a potential biomarker of aging

The skin is the only organ that shows age more profoundly. While researchers have hypothesized about the ravages of time on skin and also the epidermal stem cells that undergo differentiation to restore the external layer of the skin, no suitable method is available to assess their aging at the molecular level.

22 Jul 2020

Researchers comprehensively describe the 'human tissue virome atlas'

Human-resident microbes can influence both health and disease. Investigating the microbiome using next-generation sequencing technology has revealed examples of mutualism and conflict between microbes and humans.

22 Jul 2020

Study explores the genetic and molecular basis of PD-L2 regulation

In immune-related disorders, therapy often involves identifying the molecules responsible for immune dysregulation and targeting them using drugs.

22 Jul 2020

Silver-plated gold nanostars could be used to detect early cancer biomarkers

Biomedical engineers at Duke University have engineered a method for simultaneously detecting the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification.

22 Jul 2020

Researchers image the formation of four-stranded DNA in living human cells

The development of four-stranded DNA has been monitored in the living cells of human beings, enabling researchers to observe its potential role in cancer.

21 Jul 2020

Newly discovered protein could be an important target to prevent prostate cancer metastases

Researchers from Boston University School of Medicine (BUSM) have discovered that the protein BRD4 could be an important new target to prevent castration-resistant prostate cancer metastases.

21 Jul 2020

Study focuses on how relationship between plants and microbes responds to drought conditions

Just below ground, an ancient and poorly understood relationship plays out between plants and microbes that infuse the soil.

17 Jul 2020

New study can help develop novel drugs for prostate cancer

The androgen receptor is considered the main driver of the growth and initiation of prostate cancer, which is known to be the second-leading cause of death in men.

15 Jul 2020

HLA-G gene linked to male-to-female ratio at birth, survival of fetuses, and preeclampsia

Preeclampsia is globally a leading cause of illness and deaths among mothers and their babies. This severe pregnancy disorder occurs in up to five percent of all pregnancies.

15 Jul 2020

Study shows mismatched caregiver-infant interactions can increase risk of later obesity

Infancy is a sensitive developmental period that presents opportunities and challenges for caregivers to feed their infants in ways that support healthy growth and development.

14 Jul 2020

Single-nucleus RNA sequencing helps compare transcriptional responses to acute cocaine

The lab of Jeremy Day, Ph.D., at the University of Alabama at Birmingham, has used single-nucleus RNA sequencing approaches to compare transcriptional responses to acute cocaine in 16 unique cell populations from a portion of the brain called the nucleus accumbens, or NAc.

From University of Alabama 10 Jul 2020

Metabolomics can help understand the impact of calorie-restricted diets on aging

Changes in a few small molecules involved in a cell's metabolism seem to indicate whether a restricted "life extension" diet will actually extend, shorten, or have no effect on lifespan, a study of fruit flies has found.

10 Jul 2020

Researchers map non-coding, 'functional' genome in maize during early development

Growth and development of all organisms depends on coordinated regulation of gene expression in time and space, and this is largely controlled by non-coding sequences in the genome.

8 Jul 2020

Lessons from early embryo could increase the efficiency of cell reprogramming

Cell reprogramming provides an outstanding opportunity for the artificial generation of stem cells for regenerative medicine approaches in the clinic.

7 Jul 2020

COVID-19 makes platelets 'hyperactive' and more prone to form deadly blood clots

Changes in blood platelets triggered by COVID-19 could contribute to the onset of heart attacks, strokes, and other serious complications in some patients who have the disease, according to University of Utah Health scientists.

2 Jul 2020

Discovery of novel mechanism associated with cancer could lead to new therapies

Cancer cases have been rising over the years and according to the statistics, the number of people living with cancer will continue to increase.

2 Jul 2020

Discovery of new step in brain cell mechanism could lead to new treatments for epilepsy

Researchers have identified a critical new step in how brain cells function in people with one of the most common forms of epilepsy.

2 Jul 2020

Scientists develop CRISPR-assisted method to detect RNA-binding proteins in living cells

While scientists still don't fully understand the diverse nature of RNA molecules, it is believed that the proteins binding to them, called RNA-binding proteins, are associated with many disease formation.

2 Jul 2020

Researchers develop a series of APOBEC-Cas9 fusion-induced deletion systems

Many small regulatory elements, including miRNAs, miRNA binding sites, and cis-acting elements, comprise only 5~24 nucleotides and play important roles in regulating gene expression, transcription and translation, and protein structure, and thus are promising targets for gene function studies and crop improvement.

1 Jul 2020

Gene Expression News and Research

Further Reading

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

Researchers identify a potential biomarker of aging

Researchers comprehensively describe the 'human tissue virome atlas'

Study explores the genetic and molecular basis of PD-L2 regulation

Silver-plated gold nanostars could be used to detect early cancer biomarkers

Researchers image the formation of four-stranded DNA in living human cells

Newly discovered protein could be an important target to prevent prostate cancer metastases

Study focuses on how relationship between plants and microbes responds to drought conditions

New study can help develop novel drugs for prostate cancer

HLA-G gene linked to male-to-female ratio at birth, survival of fetuses, and preeclampsia

Study shows mismatched caregiver-infant interactions can increase risk of later obesity

Single-nucleus RNA sequencing helps compare transcriptional responses to acute cocaine

Metabolomics can help understand the impact of calorie-restricted diets on aging

Researchers map non-coding, 'functional' genome in maize during early development

Lessons from early embryo could increase the efficiency of cell reprogramming

COVID-19 makes platelets 'hyperactive' and more prone to form deadly blood clots

Discovery of novel mechanism associated with cancer could lead to new therapies

Discovery of new step in brain cell mechanism could lead to new treatments for epilepsy

Scientists develop CRISPR-assisted method to detect RNA-binding proteins in living cells

Researchers develop a series of APOBEC-Cas9 fusion-induced deletion systems

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