Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Newly developed toolkit uses small molecules to control the activity of synthetic RNA

The Okinawa Institute of Science and Technology, in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses small molecules to control the activity of a piece of synthetic RNA, and ultimately regulate gene expression.

31 Mar 2023

SARS-CoV-2 infection hijacks and damages parts of infected cells' vital RNA machinery

Coronavirus disease (COVID-19) hijacks parts of infected cells' vital RNA machinery, thereby blocking important functions in the cells. These damaging changes in the RNA can likely be reversed, potentially leading to new drugs against COVID-19, University of Gothenburg researchers show.

30 Mar 2023

Analyzing the GmZF351 transgenic soybean plants and their stress tolerance

Across the globe, soybean is considered to be an important food, oil, and feed crop worldwide.

29 Mar 2023

The proper implementation of stem cell-based disease models

Scientists have learned how to manufacture induced pluripotent stem cells (iPSC) from regular cells through genetic reprogramming during the last ten years.

29 Mar 2023

Finding how the global regulation factor reshapes the cell-fate-decision landscape

Determining cell differentiation trajectories has been done by genes and the regulation relationships among them creating complicated networks.

28 Mar 2023

Heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of gut microbes

A new study examining the gene expression of gut microbes suggests that the heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of microbes found in our gut.

27 Mar 2023

Meta-scale approach to quantifying the protein variants in the human body

A key conundrum in biology is why many very simple creatures, such as the widely studied worm C. elegans, have almost as many genes as the human genome, which has about 20,000 genes.

27 Mar 2023

Analyzing how the global regulation factor reshapes the cell-fate-decision landscape

Genes and their regulatory relationships form complex networks that govern cell differentiation trajectories. However, predicting and understanding cell fate decisions using bottom-up network topology is still side-lined.

27 Mar 2023

Walnuts might support heart health by changing the gut microbiome

Scientists at Texas Tech University have revealed that the heart-healthy benefits of eating walnuts could be a result of the changes they induce in the gut microbiome.

24 Mar 2023

Revealing how hematopoietic stem cells acquire malignant traits in cancer

Scientists from Lund University’s Faculty of Medicine have discovered a novel mechanism connecting ribonucleic acid (RNA) metabolism to the development of leukemia in patients with myelodysplastic syndrome (MDS).

23 Mar 2023

CABBI/GLBRC researchers peer into the complexities of life on a leaf

"Have you ever wondered about life on a leaf?" Great Lakes Bioenergy Research Center (GLBRC) researcher Ashley Shade asks a simple question, but it's one well worth investigation.

22 Mar 2023

Losing a productive type of beta cell may contribute to the development of diabetes

Multiple types of beta cells produce insulin in the pancreas, helping to balance blood sugar levels. Losing a particularly productive type of beta cell may contribute to the development of diabetes, according to a new study by Weill Cornell Medicine investigators.

17 Mar 2023

The impact of genome doubling on the development of cancer

Since a single cell has 2–3 m of DNA, the only method to store it is in tight coils. The answer is chromatin, a DNA-protein complex that is wrapped around histone proteins.

17 Mar 2023

Novel web-based tool deoptimizes genetic sequences based on different codon usage

A new software tool developed by Texas Biomedical Research Institute and collaborators can help scientists and vaccine developers quickly edit genetic blueprints of pathogens to make them less harmful.

16 Mar 2023

Study examines the role of dietary vitamin A in preventing or treating AAP

Consuming a diet rich in vitamin A or its analogs may help prevent children and young adults with acute lymphoblastic leukemia (ALL) reduce their risk of developing painful pancreas inflammation during chemotherapy treatment.

16 Mar 2023

Rice biologists embark on a three-year project to create genetically encoded antibiotics

Synthetic biologists at Rice University are embarking on a three-year project to create "genetically encoded antibiotics," strands of RNA that bacteria will readily copy and share that will selectively kill only disease-causing, pathogenic bacteria.

14 Mar 2023

SMART researchers develop the world's first microneedle-based drug delivery technique for plants

Researchers from the Disruptive & Sustainable Technologies for Agricultural Precision (DiSTAP) Interdisciplinary Research Group (IRG) of Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, and their collaborators from Temasek Life Sciences Laboratory (TLL) and Massachusetts Institute of Technology (MIT), have developed the first-ever microneedle-based drug delivery technique for plants.

14 Mar 2023

Significance of astrocyte–neuron interactions in fine-tuning brain function

Humans learn to handle a variety of skilled movements throughout their lives, from driving a car to swinging a tennis racket. Neurons are not the only ones who implement this learning, but a new study from The Picower Institute for Learning and Memory at MIT shows that astrocytes play an important role as well.

From Massachusetts Institute of Technology (MIT) 14 Mar 2023

New class of oral drugs inhibits a diverse range of SARS-CoV-2 strains

The constant evolution of new COVID-19 variants makes it critical for clinicians to have multiple therapies in their arsenal for treating drug-resistant infections. Researchers have now discovered that a new class of oral drugs that acts directly on human cells can inhibit a diverse range of pathogenic SARS-CoV-2 strains.

13 Mar 2023

A reliable way to downregulate gene translation in plants

By carefully constructing upstream open reading frames (uORFs), Caixia Gao’s team at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences (CAS) has created a new technique for downregulating gene translation to a predictable and desirable level in plants.

10 Mar 2023

Gene Expression News and Research

Further Reading

Newly developed toolkit uses small molecules to control the activity of synthetic RNA

SARS-CoV-2 infection hijacks and damages parts of infected cells' vital RNA machinery

Analyzing the GmZF351 transgenic soybean plants and their stress tolerance

The proper implementation of stem cell-based disease models

Finding how the global regulation factor reshapes the cell-fate-decision landscape

Heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of gut microbes

Meta-scale approach to quantifying the protein variants in the human body

Analyzing how the global regulation factor reshapes the cell-fate-decision landscape

Walnuts might support heart health by changing the gut microbiome

Revealing how hematopoietic stem cells acquire malignant traits in cancer

CABBI/GLBRC researchers peer into the complexities of life on a leaf

Losing a productive type of beta cell may contribute to the development of diabetes

The impact of genome doubling on the development of cancer

Novel web-based tool deoptimizes genetic sequences based on different codon usage

Study examines the role of dietary vitamin A in preventing or treating AAP

Rice biologists embark on a three-year project to create genetically encoded antibiotics

SMART researchers develop the world's first microneedle-based drug delivery technique for plants

Significance of astrocyte–neuron interactions in fine-tuning brain function

New class of oral drugs inhibits a diverse range of SARS-CoV-2 strains

A reliable way to downregulate gene translation in plants

How can the adoption of AI technology accelerate drug discovery?

Gaining insights into human disease biology through CRISPR platforms

Genome Editing Has A New Code

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